The overarching objectives of CaMos are:

  • to examine the development and demographics of osteoporosis;
  • to identify risk factors for osteoporotic fractures (e.g. genetic risk factors, calcium and vitamin D intake and serum levels, proton pump inhibitors, physical activities) and their associations with BMD, fractures, and/or mortality; and
  • to assess outcomes of osteoporosis and treatment.

Study Design

Study Design Cohort
General Information on Follow Up (profile, frequency)

Participants were followed annually by postal questionnaire to obtain medication and fracture history. Details regarding reported fractures were obtained through a telephone interview. The data collection at Year 3 (participants aged 40-60 years), Year 5 (all participants), Year 10 (all participants) and Year 16 (women aged 60-75 years) follow-ups included an extensive interviewer-administered questionnaire and a clinical assessment (bone mineral density, X-rays, ultrasounds, height and weight measurements). Participants not selected to do a full interview at Year 3 and 16 follow-ups, received a short postal follow-up questionnaire on fractures. 

Recruitment Target
  • Individuals
Number of Participants

10,424

Number of Participants with Biosamples

(No Limit)

Supplementary Information about Number of Participants

6539 women and 2884 men aged 25 years and older; 527 young women and 474 young men aged 16-24 years.

Supplementary Information

The Canadian Multicentre Osteoporosis Study (CaMos) is an ongoing population-based longitudinal study of community-dwelling adults (ages 25 years and older) recruited from 1995 to 1997. Between 2004 and 2006, a cohort of young women and men 16-24 years old was also recruited. Both cohorts have been drawn from a random population-based sample of non-institutionalized men and women living within 50 km of one of nine Canadian cities (St John’s, Halifax, Quebec City, Kingston, Toronto, Hamilton, Saskatoon, Calgary and Vancouver), referred to as centres, encompassing roughly 40% of the Canadian population. Households were randomly selected from residential phone numbers; participants were then selected from households by an age-stratified protocol. In the adult cohort (ages 25 years and older), this protocol weighted to older adults with two thirds women.

Access

Yes
No
Not Applicable
Don't know
Possible Access to Data

Possible Access to Biosamples

Other

All CaMos data are accessible to external researchers as long as they collaborate with one of the CaMos investigators.

Marker Paper

Kreiger N, Tenenhouse A, Joseph L, Mackenzie T, Poliquin S, Brown JP, Prior JC, Rittmaster RS. (1999) The Canadian Multicentre Osteoporosis Study (CaMos): Background, rationale, methods. Can J Aging 18(3):376-87

Study Timeline

Each colour in the timeline graph below represents a separate Study Population, while each segment in the graph represents a separate Data Collection Event. Clicking on a segment gives more detailed information on a Data Collection Event.

Populations

CaMos - Adult Cohort (25 years and older)

The adult cohort includes non-institutionalized men and women aged 25 years or older living within 50 km of one of nine Canadian cities.

Sources of Recruitment

General Population
  • Selected sample

Selection Criteria

Age Minimum age 25
Country Canada
Territory

Living within 50 km of one of nine Canadian cities (St John’s, Halifax, Quebec City, Kingston, Toronto, Hamilton, Saskatoon, Calgary and Vancouver)

Other

Random selection of non-institutionalized adults

Sample Size

Number of Participants

9,423

Number of Participants with Biosamples

(No Limit)

Supplementary Information about Number of Participants

6539 women and 2884 men

Data Collection Events

NameDescriptionStartEnd
CaMos - Adult Cohort - Baseline

Baseline recruitment. Full interview with bone...

1995 (July)1997 (September)
CaMos - Adult Cohort - Year 1 Follow-up

Mailed questionnaire asking about fractures,...

1996 (August)1998 (December)
CaMos - Adult Cohort - Year 2 Follow-up

Mailed questionnaire asking about fractures,...

1997 (July)2000 (February)
CaMos - Adult Cohort - Year 3 Follow-up

Full interview with bone mineral density,...

1998 (July)2001 (January)
CaMos - Adult Cohort - Year 4 Follow-up

Mailed questionnaire asking about fractures,...

1999 (January)2001 (December)
CaMos - Adult Cohort - Year 5 Follow-up

Full interview with bone mineral density, X-ray...

2001 (December)2004 (January)
CaMos - Adult Cohort - Year 6 Follow-up

Mailed questionnaire asking about fractures,...

2002 (August)2004 (December)
CaMos - Adult Cohort - Year 7 Follow-up

Mailed questionnaire asking about fractures,...

2003 (November)2006 (February)
CaMos - Adult Cohort - Year 8 Follow-up

Mailed questionnaire asking about fractures,...

2004 (October)2007 (January)
CaMos - Adult Cohort - Year 9 Follow-up

Mailed questionnaire asking about fractures,...

2006 (September)2009 (January)
CaMos - Adult Cohort - Year 10 Follow-up

Full interview with bone mineral density, X-ray...

2007 (July)2010 (January)
CaMos - Adult Cohort - Year 11 Follow-up

Mailed questionnaire asking about fractures,...

2008 (September)2011 (April)
CaMos - Adult Cohort - Year 12 Follow-up

Mailed questionnaire asking about fractures,...

2009 (August)2011 (November)
CaMos - Adult Cohort - Year 13 Follow-up

Mailed questionnaire asking about fractures,...

2011 (March)2012 (September)
CaMos - Adult Cohort - Year 14 Follow-up

Mailed questionnaire asking about fractures,...

2012 (January)2013 (December)
CaMos - Adult Cohort - Year 15 Follow-up

Mailed questionnaire asking about fractures,...

2013 (January)2013 (December)
CaMos - Adult Cohort - Year 16 Follow-up

Full interview (in women 60-75/85) with bone...

2014 (January)2014 (December)
CaMos - Adult Cohort - Year 17 Follow-up

Mailed questionnaire asking about fractures,...

2015 (January)2015 (December)
CaMos - Adult Cohort - Year 18 Follow-up

Mailed questionnaire asking about fractures,...

2016 (January)2016 (December)
CaMos - Adult Cohort - Year 19 Follow-up

Mailed questionnaire asking about fractures,...

2017 (January)2017 (December)
CaMos - Adult Cohort - Year 20 Follow-up

Mailed questionnaire asking about fractures,...

2018 (January)2018 (December)

CaMos - Youth Cohort (16-24 years old)

The youth cohort includes young men and women aged 16-24 years living within 50 km of one of nine Canadian cities. The same recruitment method as with the adult cohort was used. However, there were no oversampling.

Sources of Recruitment

General Population
  • Selected sample

Selection Criteria

Age Minimum age 16, Maximum age 24
Country Canada
Territory

Living within 50 km of one of nine Canadian cities (St John’s, Halifax, Quebec City, Kingston, Toronto, Hamilton, Saskatoon, Calgary and Vancouver)

Other

Random selection through phone directory

Sample Size

Number of Participants

1,001

Number of Participants with Biosamples

(No Limit)

Supplementary Information about Number of Participants

527 women and 474 men

Data Collection Events

NameDescriptionStartEnd
CaMos - Youth Cohort - Baseline

Baseline recruitment. Full interview with bone...

2004 (July)2006 (June)
CaMos - Youth Cohort - Year 1 Follow-up

Short follow-up on fractures and medications,...

2005 (September)2008 (February)
CaMos -Youth Cohort - Year 2 Follow-up

Full interview with bone mineral density,...

2006 (August)2008 (December)
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Variable Classification