The initial aims of the study were to examine the importance of lipids, haemostatic factors, and hormones such as testosterone, cortisol and insulin (Lichtenstein et al 1987) in the development of ischaemic heart disease (IHD). Subsequently, other hypotheses were included with a specific interest in platelet function, and psychosocial variables. With the ageing of the cohort, additional outcomes have been included in particular stroke, hearing problems and cognitive function.

Study Design

Study Design Cohort
Recruitment Target
  • Individuals
Number of Participants

2,959

Number of Participants with Biosamples

1,500

Supplementary Information about Number of Participants

The target number of participants with biological samples varies depending on type of sample.

Access

Access to external researchers or third parties provided or foreseen.

Data (questionnaire-derived, measured...)

Biosamples

Other Access

If approved by access committee

Study Timeline

Each colour in the timeline graph below represents a separate Study Population, while each segment in the graph represents a separate Data Collection Event. Clicking on a segment gives more detailed information on a Data Collection Event.

Populations

Caerphilly Cohort

The population consist of men aged 45-59 years living in and around the town of Caerphilly, South Wales.

Sources of Recruitment

General Population
  • Selected sample
Supplementary Information

Subjects were identified from the electoral register and general practice lists.

Selection Criteria

Gender Men only
Age Minimum age 45, Maximum age 59
Country United Kingdom
Territory

Caerphilly, South Wales

Sample Size

Number of Participants

2,959

Number of Participants with Biosamples

1,500

Supplementary Information about Number of Participants

The number of participants with biological samples varies depending on type of sample.

Data Collection Events

NameDescriptionStartEnd
Phase I

Men were seen at an evening clinic, where...

1979 (July)1983 (September)
Phase II

 Follow-up of participants. Same test as...

1984 (July)1988 (June)
Phase III

Second follow-up of participants. Same methods...

1989 (November)1993 (September)
Phase IV

Third follow-up of participants.&nbsp...

1993 (October)1997 (February)
Follow-up research

Data on stroke events as well as new non-fatal...

1997 (March)2016 (December)
Phase V

Fourth follow-up of participants. Repeat...

2002 (January)2004 (December)
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Variable Classification