Information was collected through a questionnaire and a Health Screening Center (HSC) visit for a comprehensive health examination. Information was collected on health and lifestyle as well as job history which was linked to the MATGENE job-exposure matrices to establish cumulative indices of exposure to various occupational hazards. The Jenkins Sleepiness Scale was also used to assess sleep.

Information about alcohol use was collected with the AUDIT (Alcohol Use Disorders Identification Test) and the AUDIT-C (Alcohol Use Disorders Identification Test-Consumption). Cognitive function is assessed through the Mini Mental State Exam, trail making A and B, Weschler's coding subtest, finger tapping test, free and cued recall (RL/RI16), word fluency, formal lexical and semantic evocation, Grober and Busckhe's memory tests. For participants aged 45+ years, an evaluation of specific health problems of the elderly is also performed and comprises the Instumental Activities of Daily Living and the French Handicaps-Disabilities-Impairments Survey, assessing the ability to use new technologies.

At the health screening center, weight, height, blood pressure, vision, auditory measures were taken and an electrocardiogram and spirometry were carried out. Physical functioning is assessed through gait speed, balance and hand grip tests.

Blood and urine samples were collected.

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

Information was collected through a questionnaire and a Health Screening Center (HSC) visit for a comprehensive health examination. Information was collected on health and lifestyle as well as job history which was linked to the MATGENE job-exposure matrices to establish cumulative indices of exposure to various occupational hazards. The Jenkins Sleepiness Scale was also used to assess sleep.

Information about alcohol use was collected with the AUDIT (Alcohol Use Disorders Identification Test) and the AUDIT-C (Alcohol Use Disorders Identification Test-Consumption). Cognitive function is assessed through the Mini Mental State Exam, trail making A and B, Weschler's coding subtest, finger tapping test, free and cued recall (RL/RI16), word fluency, formal lexical and semantic evocation, Grober and Busckhe's memory tests. For participants aged 45+ years, an evaluation of specific health problems of the elderly is also performed and comprises the Instumental Activities of Daily Living and the French Handicaps-Disabilities-Impairments Survey, assessing the ability to use new technologies.

At the health screening center, weight, height, blood pressure, vision, auditory measures were taken and an electrocardiogram and spirometry were carried out. Physical functioning is assessed through gait speed, balance and hand grip tests.

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, socioeconomic status of parents and spouse and material living condition), health (personal and family history, self-reported health scales, incident and prevalent diseases, information on sick leaves, handicaps, limitations, disabilities and injuries, and health care utilization and management), behavior (smoking and alcohol consumption, dietary habits, physical activity, marijuana use and sexual orientation) and occupational factors (job history, lifelong and current occupational exposure to chemical, physical and biological agents, postural. mechanical and organizational constraints, and stress at work). Sleep was also assessed using The Jenkins Sleepiness Scale.

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, socioeconomic status of parents and spouse and material living condition), health (personal and family history, self-reported health scales, incident and prevalent diseases, information on sick leaves, handicaps, limitations, disabilities and injuries, and health care utilization and management), behavior (smoking and alcohol consumption, dietary habits, physical activity, marijuana use and sexual orientation) and occupational factors (job history, lifelong and current occupational exposure to chemical, physical and biological agents, postural. mechanical and organizational constraints, and stress at work). Sleep was also assessed using The Jenkins Sleepiness Scale.

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, socioeconomic status of parents and spouse and material living condition), health (personal and family history, self-reported health scales, incident and prevalent diseases, information on sick leaves, handicaps, limitations, disabilities and injuries, and health care utilization and management), behavior (smoking and alcohol consumption, dietary habits, physical activity, marijuana use and sexual orientation) and occupational factors (job history, lifelong and current occupational exposure to chemical, physical and biological agents, postural. mechanical and organizational constraints, and stress at work). Information was also collected about urinary incontinence using the International Consultation on Incontinence Questionnaire (ICIQ).

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

Information was collected through a questionnaire and a Health Screening Center (HSC) visit for a comprehensive health examination. Information was collected on health and lifestyle as well as job history which was linked to the MATGENE job-exposure matrices to establish cumulative indices of exposure to various occupational hazards. The Jenkins Sleepiness Scale was also used to assess sleep.

Information about alcohol use was collected with the AUDIT (Alcohol Use Disorders Identification Test) and the AUDIT-C (Alcohol Use Disorders Identification Test-Consumption). Cognitive function is assessed through the Mini Mental State Exam, trail making A and B, Weschler's coding subtest, finger tapping test, free and cued recall (RL/RI16), word fluency, formal lexical and semantic evocation, Grober and Busckhe's memory tests. For participants aged 45+ years, an evaluation of specific health problems of the elderly is also performed and comprises the Instumental Activities of Daily Living and the French Handicaps-Disabilities-Impairments Survey, assessing the ability to use new technologies.

At the health screening center, weight, height, blood pressure, vision, auditory measures were taken and an electrocardiogram and spirometry were carried out. Physical functioning is assessed through gait speed, balance and hand grip tests.

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, socioeconomic status of parents and spouse and material living condition), health (personal and family history, self-reported health scales, incident and prevalent diseases, information on sick leaves, handicaps, limitations, disabilities and injuries, and health care utilization and management), behavior (smoking and alcohol consumption, dietary habits, physical activity, marijuana use and sexual orientation) and occupational factors (job history, lifelong and current occupational exposure to chemical, physical and biological agents, postural. mechanical and organizational constraints, and stress at work). Sleep was also assessed using The Jenkins Sleepiness Scale.

Information on eating disorders was collected using the SCOFF questionnaire.

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, socioeconomic status of parents and spouse and material living condition), health (personal and family history, self-reported health scales, incident and prevalent diseases, information on sick leaves, handicaps, limitations, disabilities and injuries, and health care utilization and management), behavior (smoking and alcohol consumption, dietary habits, physical activity, marijuana use and sexual orientation) and occupational factors (job history, lifelong and current occupational exposure to chemical, physical and biological agents, postural. mechanical and organizational constraints, and stress at work). Quality of life information was collected using the GHQ12 questionnaire.

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, socioeconomic status of parents and spouse and material living condition), health (personal and family history, self-reported health scales, incident and prevalent diseases, information on sick leaves, handicaps, limitations, disabilities and injuries, and health care utilization and management), behavior (smoking and alcohol consumption, dietary habits, physical activity, marijuana use and sexual orientation) and occupational factors (job history, lifelong and current occupational exposure to chemical, physical and biological agents, postural. mechanical and organizational constraints, and stress at work). Quality of life information was collected using the GHQ12 questionnaire.

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, socioeconomic status of parents and spouse and material living condition), health (personal and family history, self-reported health scales, incident and prevalent diseases, information on sick leaves, handicaps, limitations, disabilities and injuries, and health care utilization and management), behavior (smoking and alcohol consumption, dietary habits, physical activity, marijuana use and sexual orientation) and occupational factors (job history, lifelong and current occupational exposure to chemical, physical and biological agents, postural. mechanical and organizational constraints, and stress at work). The Jenkins and Epworth Sleepiness Scale were used to assess sleep. Information about physical activity was collected with the International Physical Activity Questionnaire (IPAQ) and quality of life information was collected using the GHQ12 questionnaire.

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

At the Health Center, an evaluation of specific health problems of the elderly is performed and comprises the Instrumental Activities of Daily Living questionnaire, the French Handicaps-Disabilities-Impairments Survey, assessing the ability to use new technologies, and the Critical Appraisal Skills Programme (CASP), a quality of life scale.

Cognitive function is assessed through the Mini Mental State Exam, trail making A and B, Weschler's coding subtest, finger tapping test, free and cued recall (RL/RI16), word fluency, formal lexical and semantic evocation, Grober and Busckhe's memory tests.

Weight, height, waist-hip ratio, blood pressure, electrocardiogram, vision, hearing, lung function and physical functioning (gait speed, balance and hand grip tests) are measured.

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, socioeconomic status of parents and spouse and material living condition), health (personal and family history, self-reported health scales, incident and prevalent diseases, information on sick leaves, handicaps, limitations, disabilities and injuries, and health care utilization and management), behavior (smoking and alcohol consumption, dietary habits, physical activity, marijuana use and sexual orientation) and occupational factors (job history, lifelong and current occupational exposure to chemical, physical and biological agents, postural. mechanical and organizational constraints, and stress at work). The Jenkins and Epworth Sleepiness Scale were used to assess sleep and quality of life information was collected using the GHQ12 questionnaire. Information about physical activity was collected with the International Physical Activity Questionnaire (IPAQ).

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, socioeconomic status of parents and spouse and material living condition), health (personal and family history, self-reported health scales, incident and prevalent diseases, information on sick leaves, handicaps, limitations, disabilities and injuries, and health care utilization and management), behavior (smoking and alcohol consumption, dietary habits, physical activity, marijuana use and sexual orientation) and occupational factors (job history, lifelong and current occupational exposure to chemical, physical and biological agents, postural. mechanical and organizational constraints, and stress at work). The Jenkins and Epworth Sleepiness Scale were used to assess sleep and quality of life information was collected using the GHQ12 questionnaire. Information about physical activity was collected with the International Physical Activity Questionnaire (IPAQ).

The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is obtained from the National Death Registry.

The questionnaire comprised information on social and demographic characteristics (social position, educational and income level, employment, marital status, household composition, socioeconomic status of parents and spouse and material living condition), health (personal and family history, self-reported health scales, incident and prevalent diseases, information on sick leaves, handicaps, limitations, disabilities and injuries, and health care utilization and management), behavior (smoking and alcohol consumption, dietary habits, physical activity, marijuana use and sexual orientation) and occupational factors (job history, lifelong and current occupational exposure to chemical, physical and biological agents, postural, mechanical and organizational constraints, and stress at work). In 2020, the questionnaire included also items on tattoos, sleep, environmental and home exposure to pesticides, drinking water and swimming pool attendance, adverse life events in childhood. The participants are also followed-up passively for social and work-related events and health data by regular linkage with the national databases. Vital status and cause of death is also obtained from these sources.