Cohorte des consultants des Centres d'examens de santé
The objective of the CONSTANCES project is to set-up a large population-based cohort to contribute to the development of epidemiologic research and to provide useful public health information. The aging-related scientific objectives in CONSTANCES involve the study of the role of various types of risk factors throughout the life course. Another objective is to document the determinants of health most frequently encountered or suspected in chronic age-related diseases.
Overview
- Acronym
- CONSTANCES
- Website
- CONSTANCES
- Investigators
-
- Contacts
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General Design
- Study design
- Cohort
- Start - End Year
- 2012 -
- General Information on Follow Up (profile, frequency)
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The self-administered questionnaire is sent annually. Participants are also asked to go to the Health Screening Center every four years for medical and laboratory examinations. Moreover, health and socio-professional data, along with causes of death, are regularly retrieved from the national health insurance, retirement pension fund and mortality databases.
- Recruitment Target
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- Individuals
- Number of Participants
- 220,000
- Number of Participants with Biological Samples
- 39,000
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Possible to collect additional data from cohort participants.
Marker Paper
Zins M, Goldberg M, and the CONSTANCES team. The French CONSTANCES population-based cohort: design, inclusion and follow-up. Eur J Epidemiology. 2015, 30:1317-1328
PUBMED 26520638Timeline
Population
The CONSTANCES population is composed of people in France whose health insurance is administered by the French National Health Insurance Fund (CNAM) in the catchment areas of the 21 CONSTANCES Health Screening Centers; and aged 18 to 69 years at inception.
Selection Criteria
- Minimum age
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18
- Maximum age
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69
- Countries
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- France
Sources of Recruitment
- General Population
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- Selected sample
- Supplementary Information
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Participants are drawn randomly from the persons covered by the French National Health Insurance Fund (CNAM). Everyone with health insurance from CNAM as well as their dependents, is entitled to receive health examinations that include free extensive work-ups conducted in selected Health Screening Centers (HSCs). Randomly selected persons received an invitation to come to their HSC for inclusion in the CONSTANCES cohort. Inclusion in CONSTANCES took place over a 6-year period (2012-2019).
Sample Size
- Number of Participants
- 220,000
- Number of Participants with Biological Samples
- 39,000
- Supplementary Information about selection criteria
-
Inclusion: 8000 participants
Follow-up 2013: 20 000 participants
Follow-up 2014: 25 000 participants
Follow-up 2015: 32 000 participants
Follow-up 2016: 40 000 participants
Follow-up 2017: 150 000 participants
Follow-up 2018: 185 000 participants
Follow-up 2019: 220 000 participants
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CONSTANCES - Inclusion version 1 |
|
|
2012 | 2014 |
| 1 | CONSTANCES - Inclusion version 2 |
|
2013 | 2016 | |
| 2 | CONSTANCES - Follow-up 2013 - w1 |
|
2013 (May) | 2013 (October) | |
| 3 | CONSTANCES - Follow-up 2013 - w2 |
|
2013 (November) | 2014 (April) | |
| 4 | CONSTANCES - Follow-up 2014 |
|
2014 (May) | 2015 (April) | |
| 5 | CONSTANCES - Inclusion version 3 |
|
2015 | 2019 | |
| 6 | CONSTANCES - Follow-up 2015 |
|
2015 (May) | 2016 (April) | |
| 7 | CONSTANCES - Follow-up 2016 - w1 |
|
2016 (May) | 2016 (October) | |
| 8 | CONSTANCES - Follow-up 2016 - w2 |
|
2016 (November) | 2017 (April) | |
| 9 | CONSTANCES - Follow-up 2017 |
|
2017 (May) | 2018 (April) | |
| 10 | CONSTANCES - Health exam |
|
2017 (May) | 2019 (November) | |
| 11 | CONSTANCES - Follow-up 2018 |
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2018 (May) | 2019 (April) | |
| 12 | CONSTANCES - Follow-up 2019 |
|
2019 (May) | 2020 (April) | |
| 13 | CONSTANCES - Follow-up 2020 |
|
2020 (September) | 2021 (May) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
Areas of Information Collected per per Population and Data Collection Event
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|