The primary objective of the EpiHealth cohort study is to provide an open-access resource to study interactions between genotypes and life-style factors in a large cohort (300 000 individuals) derived from the Swedish population in the ages 45 to 75 years regarding the future development of common degenerative disorders, such as myocardial infarction, stroke, heart failure, fractures/osteoporosis, dementia, obstructive lung disease, osteoarthritis/pain, obesity/type 2 diabetes, and cancer. Moreover, secondary objectives of EpiHealth are:

  • To study prevalence’s of common degenerative disorders in the Swedish population in the ages 45-75 years;
  • To study life-style patterns in the ages 45-75 years and differences between genders;
  • To study heritability of common degenerative disorders in the Swedish population by using data from families attending both EpiHealth and LifeGene studies;
  • To evaluate novel biomarkers in serum and plasma for future common degenerative disorders;
  • To study the relationships between genotypes and future development of common degenerative disorders;
  • To study the relationships between life-style factors and future development of common degenerative disorders.

Overview

Acronym

EpiHealth

Website

EpiHealth Website

Contacts
Start Year

2011

General Design

Study Design Cohort
General Information on Follow Up (profile, frequency)

Following the baseline investigation, repeated collection of data on exposures from the web-based questionnaires and test center visits are planned for every 5th and 10th year respectively.

Recruitment Target
  • Individuals
Number of Participants

300,000

Number of Participants with Biological Samples

300,000

Access

Yes
No
Not Applicable
Don't Know
Possible Access to Data

Possible Access to Biosamples

Other

Marker Paper

Lind L, Elmståhl S, Bergman E, Englund M, Lindberg E, Michaelsson K, Nilsson PM, Sundström J. EpiHealth: a large population-based cohort study for investigation of gene-lifestyle interactions in the pathogenesis of common diseases. Eur J Epidemiol. 2013 Feb; 28(2): 189-97.

PUBMED 23435790

Study Timeline

Each colour in the timeline graph below represents a separate Study Population, while each segment in the graph represents a separate Data Collection Event. Clicking on a segment gives more detailed information on a Data Collection Event.

Population

EpiHealth - Population

The study population is composed of persons aged between 45 and 75 years, who have a permanent address in Sweden and a civic registration number.

Sources of Recruitment

General Population
  • Selected sample
Supplementary Information A randomization procedure will assure that all age-groups and both genders are equally represented in the main study. The majority of the sample will be included based on population-based randomization using official registries and/or commercial address databases.

Selection Criteria

Age Minimum age 45, Maximum age 75
Country Sweden

Sample Size

Number of Participants

300,000

Number of Participants with Biological Samples

300,000

Data Collection Events

NameDescriptionStartEnd
EpiHealth - Baseline

During the baseline investigation, data...

2011 (April)2016 (December)
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Variables classifications