The Washington Heights-Inwood Columbia Aging Project (WHICAP) objectives are to identify risk factors and biomarkers for aging and Alzheimer's disease in a multi-ethnic cohort which includes Caucasian, African-American and Hispanic participants.

General Design

Study Design Cohort
General Information on Follow Up (profile, frequency)

Participants of WHICAP I were followed-up at intervals of 24 months and the participants of WHICAP II are followed-up at intervals of 18 months for a maximum of 4 assessments (baseline + 3 follow-ups).

Recruitment Target
  • Individuals
Number of Participants

4,308

Number of Participants with Biological Samples

4,308

Access

Yes
No
Not Applicable
Don't Know
Possible Access to Data

Possible Access to Biosamples

Other

Marker Paper

Tang MX, Cross P, Andrews H, Jacobs DM, Small S, Bell K, Merchant C, Lantigua R, Costa R, Stern Y, Mayeux R. Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan. Neurology, 2001; 56(1): 49-56.

PUBMED 11148235

Study Timeline

Each colour in the timeline graph below represents a separate Study Population, while each segment in the graph represents a separate Data Collection Event. Clicking on a segment gives more detailed information on a Data Collection Event.

Populations

WHICAP I

Participants were healthy Medicare beneficiaries without dementia, aged 65 years and older in 1992-1994, and residing in 3 contiguous ZIP codes within the community of Washington Heights in northern New York City.

Sources of Recruitment

Specific Population
  • Members of an association
Supplementary Information

Participants were randomly drawn from lists of all Medicare or Medicaid recipients in the study area, which were obtained from Health Care Financing Administration.

Selection Criteria

Age Minimum age 65
Country United States of America
Territory

Washington Heights and Inwood in New York

Ethnic Origin African-Americans, Caribbean Hispanics, Caucasians
Other

Participants had to reside in the community during baseline and speak English or Spanish.

Sample Size

Number of Participants

2,125

Number of Participants with Biological Samples

2,125

Data Collection Events

NameDescriptionStartEnd
WHICAP I - Baseline

The majority of assessments were performed in...

19921994
WHICAP I - Follow-up 1

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19941996
WHICAP I - Follow-up 2

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19961998
WHICAP I - Follow-up 3

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19981999

WHICAP II

The WHICAP II cohort represents a combination of continuing participants of WHICAP I (n = 602) and newly recruited participants (n = 2183). Participants were again healthy Medicare beneficiaries without dementia, aged 65 years and older in 1999-2001, and residing in 3 contiguous ZIP codes within the community of Washington Heights in northern New York City.

Sources of Recruitment

Specific Population
  • Members of an association
Supplementary Information

Participants were randomly drawn from new lists of all Medicare or Medicaid recipients in the study area, which were obtained from Health Care Financing Administration.

Selection Criteria

Age Minimum age 65
Country United States of America
Territory

Washington Heights and Inwood in New York

Ethnic Origin African-Americans, Caribbean Hispanics, Caucasians
Other

Participants had to speak English or Spanish.

Sample Size

Number of Participants

2,785

Number of Participants with Biological Samples

2,785

Data Collection Events

NameDescriptionStartEnd
WHICAP II - Baseline

The majority of assessments were performed in...

1999 (January)2001 (December)
WHICAP II - Follow-up 1

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2000 (July)2003 (June)
WHICAP II - Follow-up 2

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2002 (January)2004 (December)
WHICAP II - Follow-up 3

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2003 (July)2006 (June)
WHICAP II - Follow-up 4

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2005 (January)2007 (December)
WHICAP II - Follow-up 5

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2006 (July)2009 (June)
WHICAP II - Follow-up 6

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2008 (January)2010 (December)
WHICAP II - Follow-up 7

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2009 (July)2012 (June)
WHICAP II - Follow-up 8

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2011 (January)2013 (December)
WHICAP II - Follow-up 9

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2012 (July)2015 (June)
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Variables classifications