Maelstrom Research

All Our Families

All Our Families (AOF) is a community-based, longitudinal pregnancy cohort developed to investigate the relationships between the prenatal and early life periods and outcomes for infants, children and mothers. AOF spans pregnancy, birth and early postpartum through childhood, and therefore provides the unique opportunity to describe the relations between prenatal events and early life development and to examine key factors that influence child and mother well-being over time. Through recognition of the unique opportunity to continue to collect relevant life course information on a large cohort of families, the main objectives of AOF have evolved to include the following: * Investigate maternal and infant outcomes during the perinatal period, with a particular emphasis on barriers and facilitators to accessing health care services in Calgary, Alberta; * Examine biological and environmental determinants of adverse birth outcomes, specifically spontaneous preterm birth; * Further investigate risk and protective factors for optimal child development, and to understand the trajectory and impact of poor maternal mental health over time.

Overview

Acronym

AOF

Website

AOF

Investigators

Dr. Suzanne Tough

University of Calgary

Dr. Sheila McDonald

University of Calgary

Dr. Katie Chaput

University of Calgary

Dr. Susan Graham

University of Calgary

Dr. Sheri Madigan

University of Calgary

Dr. Donna Slater

University of Calgary

Contacts

Dr. Suzanne Tough

University of Calgary

General Design

Study design

Cohort

Start - End Year

2008 -

General Information on Follow Up (profile, frequency)

Since recruitment, mothers have completed two questionnaires during pregnancy (less than 25 weeks and 34 to 36 weeks gestation). Children and mothers were followed up when the children were 4 months, 1, 2, 3, 5, 8 and 12 to 14 years of age. Participants who agreed to be contacted for additional research were mailed a flood impact questionnaire in the autumn of 2013 and three COVID-19 impact questionnaires between May 2020 and January 2022.

Recruitment Target

Families

Number of Participants

6,774

Number of Participants with Biological Samples

3,261

Supplementary information about number of participants

Mothers: 3387 participants
Children: 3387 participants

Supplementary Information

Starting from the COVID-19 questionnaire in 2020, youth participants may complete their own questionnaires if their mothers consent to it.

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other

Additional Information

Contact the research study team to access data: allourfamilies@ucalgary.ca

Availability of access information

On the study website : https://ucalgary.ca/allourfamilies

Sector of research

	Possible Access to Data	Possible Access to Biosamples
Investigators from the public sector
Investigators from the private sector
Investigators from not-for-profit organization

Transfer

	Possible Access to Data	Possible Access to Biosamples
Can leave the study facility
Can leave the country

Supplementary information about transfer

Anonymized, encrypted, special couriered.

Cost

Possible Access to Data	Not yet defined
Possible Access to Biosamples	Not yet defined

Cost reduction for co-analyses

Possible Access to Data
Possible Access to Biosamples

Yes

Not applicable

Don't know

Marker Papers

Tough SC, McDonald SW, Collisson BA, Graham SA, Kehler H, Kingston D, Benzies K. Cohort Profile: The All Our Babies pregnancy cohort (AOB). International Journal of Epidemiology. 2017 Feb 8. 1-13.

PUBMED 28180262

McDonald SW, Lyon AW, Benzies KM, et al,. The All Our Babies pregnancy cohort: design, methods, and participant characteristics. BMC Pregnancy Childbirth. 2013;13 Suppl 1(Suppl 1):S2. doi: 10.1186/1471-2393-13-S1-S2. Epub 2013 Jan 31.

PUBMED 23445747

Timeline

The comprehensive questionnaires completed by the women included questions about the participant's pregnancy history, health service utilization, demographics, height, weight, lifestyle, mental, psychosocial and physical health, life events, quality of life, work status, parenting morale, and breastfeeding.

Blood was collected.

Access to prenatal and birth record data, including past pregnancy history, medical history and current conditions, pregnancy complications, labour/birth outcomes, and infant health data was asked.

Start Date

2008 (May)

End Date

2010 (December)

Data sources

Questionnaires
Biosamples
Other : Medical records

Data sources - Biosamples

Blood

Blood was collected.

Access to prenatal and birth record data, including past pregnancy history, medical history and current conditions, pregnancy complications, labour/birth outcomes, and infant health data was asked.

Start Date

2008 (August)

End Date

2011 (March)

Data sources

Questionnaires
Biosamples
Other : Medical records

Data sources - Biosamples

Blood

Information was collected from prenatal and birth records of the child in the study, including past pregnancy history, medical history and current conditions (e.g. smoking, drug dependency, diabetes, heart disease, hypertension, renal disease and auto immune conditions), current pregnancy complications and labour/birth outcomes.

Start Date

2008 (August)

End Date

2011 (October)

Data sources

Other : Hospital and medical records

The questionnaires provided information regarding labour and delivery, breastfeeding and feeding, parenting, health service utilization, demographics, height, weight, lifestyle, mental, psychosocial and physical health, life events, quality of life, work status, parenting morale, and breastfeeding.

Access to prenatal and birth record data, including past pregnancy history, medical history and current conditions, pregnancy complications, labour/birth outcomes, and infant health data was asked.

Start Date

2008 (December)

End Date

2012 (February)

Data sources

Questionnaires
Other : Medical records

A questionnaire collected information about maternal physical and mental health, parenting, health care utilization, lifestyle, life events, family well-being, work-life balance/return to work and separation anxiety.

Start Date

2011 (June)

End Date

2012 (October)

Data sources

Questionnaires

A questionnaire collected information about maternal physical and mental health, parenting, health care utilization, lifestyle, life events and family well-being.

Start Date

2011 (October)

End Date

2013 (October)

Data sources

Questionnaires

A questionnaire collected information about maternal physical and mental health, parenting, health care utilization, lifestyle, life events and family well-being.

Start Date

2012 (April)

End Date

2014 (October)

Data sources

Questionnaires

Information was collected through a questionnaire to understand the impact of flooding that occurred in Calgary, Alberta, in June 2013. The questionnaire asked women about their experiences during the flood and damages incurred, help and aid provided and received, stress responses such as post-traumatic stress, psychological distress, social cohesion and relationship dynamics.

Start Date

2013 (November)

End Date

2013 (November)

Data sources

Questionnaires

A questionnaire collected information about maternal physical and mental health, parenting, health care utilization, lifestyle, life events and family well-being.

Start Date

2014 (April)

End Date

2016 (October)

Data sources

Questionnaires

A questionnaire collected information about maternal physical, psychosocial and mental health, parenting, lifestyle, well-being, family life, community; and about her children' school life, activities, screen use, health, sleep behaviours and eating habits.

Start Date

2017 (February)

End Date

2019 (October)

Data sources

Questionnaires

A questionnaire collected information about demographics, the impact of the COVID-19 pandemic, maternal health and well-being, children' s school and daily life, physical health, financial impact and relationships inside home. Tendencies to cope with stress adaptively is assessed through the Brief Resilient Coping Scale.

Start Date

2020 (May)

End Date

2020 (July)

Data sources

Questionnaires

A questionnaire collected information about the impact of the COVID-19 pandemic, maternal health and well-being, children' s school and daily life, and relationships inside home. Tendencies to cope with stress adaptively is assessed through the Brief Resilient Coping Scale.

Start Date

2021 (March)

End Date

2021 (April)

Data sources

Questionnaires

Information is collected about demographics, COVID-19 impact, perception of pandemic impact and vaccinations, physical and emotional health, housing, financial security, food security, professional life, and activities. Information is also collected on marital status, alcohol and drug consumption, close relationships, employment, financial impact, health utilization, and division of household labor. Tendencies to cope with stress adaptively is assessed through the Brief Resilient Coping Scale.

Start Date

2021 (November)

End Date

2022 (January)

Data sources

Questionnaires

Data examining determinants of maternal outcomes such as demographics, well-being perception, parental responsibilities, family and partner relationship, physical activities, drinking and smoking habits, perceived stress, and health information are collected. Information is also collected on community connections, life satisfaction, neighbourhood cohesion, social support and stressfull life events. Height and weight measures are also collected.

Start Date

2023 (January)

End Date

2023 (July)

Data sources

Questionnaires
Physical measures

Infant health information was collected from the prenatal and birth records, including gender, birth weight, birth date/time, disposition, 5 minute Apgar score, meconium resuscitation, NICU admission and congenital anomalies.

Umbilical cord blood, when retrievable, was collected following hospital births.

Start Date

2008 (August)

End Date

2011 (October)

Data sources

Biosamples
Other : Hospital and medical records

Data sources - Biosamples

Cord blood

Mothers completed a questionnaire regarding their baby's health and weight.

For those women who consented, medical records regarding infant health were also used.

Start Date

2008 (December)

End Date

2012 (February)

Data sources

Questionnaires
Other : Medical records

Mothers completed a questionnaire regarding their child’s development, health, weight, sleep, lifestyle and environment.

Start Date

2011 (June)

End Date

2012 (October)

Data sources

Questionnaires

Mothers completed a questionnaire regarding their child’s development, health, weight, sleep, lifestyle and environment.

Start Date

2011 (October)

End Date

2013 (October)

Data sources

Questionnaires

Mothers completed a questionnaire regarding their child’s development, behaviour, health, oral health, weight, sleep, lifestyle and environment.

Start Date

2012 (April)

End Date

2014 (October)

Data sources

Questionnaires

Mothers completed a questionnaire regarding their child’s development, health, behavior (Behavior Assessment System for Children), oral health, sleep, weight, recreation, screen time, lifestyle and environment.

Mothers and their children also had a laboratory visit to assess the child’s development and language abilities.

Start Date

2014 (April)

End Date

2016 (October)

Data sources

Questionnaires
Cognitive measures

Mothers completed a questionnaire regarding their child’s school life, recreation time, community resource use, screen use, health, sleep behaviours and eating habits, and development.

Start Date

2017 (February)

End Date

2019 (October)

Data sources

Questionnaires

A questionnaire collected information about demographics, the impact of the COVID-19 pandemic in daily life, social connections, school, feelings, screen time, social media use and well-being.

Start Date

2020 (July)

End Date

2020 (August)

Data sources

Questionnaires

A questionnaire collected information about the impact of the COVID-19 pandemic in daily life, social connections, school, feelings, screen time, social media use and well-being.

Start Date

2021 (March)

End Date

2021 (April)

Data sources

Questionnaires

Information is collected about the impact of the COVID-19 pandemic on daily life, community resources, physical activity, sleep, screen time, personal development, education, well-being, and behavior (Behavior Assessment System for Children). Information is also collected on bullying experiences, health, connections with adults, literacy environment, and optimism.

Start Date

2021 (November)

End Date

2022 (January)

Data sources

Questionnaires

Information is collected on youth outcomes such as education, personal development, parent and peer attachment, behavior (Behavior Assessment System for Children), well-being, social media and video game addictions, and health service utilization. Information on bullying experiences, health, anxiety climate, connections with adults, optimism, peer relationships, puberty, sleep, physical activities, and school experiences is also collected. Height and weight measures are collected.

Start Date

2023 (January)

End Date

2023 (July)

Data sources

Questionnaires
Physical measures

AOF - Mothers

The population is composed of pregnant women of at least 18 years of age, with a gestational age of less than 25 weeks, and receiving prenatal care in Calgary.

Selection Criteria

Sex

Women only

Minimum age

Pregnant Women

First trimester
Second trimester

Countries

Canada

Canadian Provinces

Alberta

Territory

Calgary

Other Criteria

Women had to be less than 25 weeks pregnant at enrollment, and accessing prenatal care in Calgary in 2008 or 2009.

Sources of Recruitment

General Population

Volunteer enrolment

Specific Population

Clinic patients

Supplementary Information

Pregnant women were recruited from primary care offices, community posters and word of mouth, and through a city-wide single provider public health laboratory service.

Sample Size

Number of Participants: 3,387
Number of Participants with Biological Samples: 1,862
Supplementary information about number of participants: 24 weeks gestation: 3363 participants
36 weeks gestation: 3184 participants
4 months postpartum: 3058 participants
1 year postpartum: 1574 participants
2 years postpartum: 1596 participants
3 years postpartum: 1994 participants
Flood: 1917 participants
5 years: 1992 participants
8 years: 2074 participants
COVID-19 questionnaire 1: 1333 participants
COVID-19 questionnaire 2: 1361 participants
COVID-19 questionnaire 3: 1280 participants
12-14 years postpartum: 1529 participants

Data Collection Events

#	Name	Data sources	Data sources - Biosamples	Start	End
0	AOF - Mothers - 24 weeks	Questionnaires Biosamples Other : Medical records	Blood	2008 (May)	2010 (December)
1	AOF - Mothers - 36 weeks	Questionnaires Biosamples Other : Medical records	Blood	2008 (August)	2011 (March)
2	AOF - Mothers - Birth	Other : Hospital and medical records		2008 (August)	2011 (October)
3	AOF - Mothers - 4 months postpartum	Questionnaires Other : Medical records		2008 (December)	2012 (February)
4	AOF - Mothers - 1 year postpartum	Questionnaires		2011 (June)	2012 (October)
5	AOF - Mothers - 2 years postpartum	Questionnaires		2011 (October)	2013 (October)
6	AOF - Mothers - 3 years postpartum	Questionnaires		2012 (April)	2014 (October)
7	AOF - Mothers - Flood questionnaire	Questionnaires		2013 (November)	2013 (November)
8	AOF - Mothers - 5 years postpartum	Questionnaires		2014 (April)	2016 (October)
9	AOF - Mothers - 8 years postpartum	Questionnaires		2017 (February)	2019 (October)
10	AOF - Mothers - COVID-19 questionnaire 1	Questionnaires		2020 (May)	2020 (July)
11	AOF - Mothers - COVID-19 questionnaire 2	Questionnaires		2021 (March)	2021 (April)
12	AOF - Mothers - COVID-19 questionnaire 3	Questionnaires		2021 (November)	2022 (January)
13	AOF - Mothers - 12-14 years postpartum	Questionnaires Physical measures		2023 (January)	2023 (July)

AOF - Children

The population is composed of the children of the women enrolled in the study.

Selection Criteria

Newborns

Countries

Canada

Canadian Provinces

Alberta

Territory

Calgary

Sources of Recruitment

Specific Population

Other specific population : Children of the women already recruited in the study.

Sample Size

Number of Participants: 3,058
Number of Participants with Biological Samples: 1,399
Supplementary information about number of participants: 4 months postpartum: 3039 participants
1 year postpartum: 2614 participants
2 years postpartum: 1596 participants
3 years postpartum: 1994 participants
5 years postpartum: 1992 participants
8years postpartum: 1333 participants
1st COVID-19: 893 participants
2nd COVID-19: 1045 participants
3rd COVID-19: 1034 participants
12-14 years postpartum: 1317 participants

Data Collection Events

#	Name	Data sources	Data sources - Biosamples	Start	End
0	AOF - Children - Birth	Biosamples Other : Hospital and medical records	Cord blood	2008 (August)	2011 (October)
1	AOF - Children - 4 months postpartum	Questionnaires Other : Medical records		2008 (December)	2012 (February)
2	AOF - Children - 1 year postpartum	Questionnaires		2011 (June)	2012 (October)
3	AOF - Children - 2 years postpartum	Questionnaires		2011 (October)	2013 (October)
4	AOF - Children - 3 years postpartum	Questionnaires		2012 (April)	2014 (October)
5	AOF - Children - 5 years postpartum	Questionnaires Cognitive measures		2014 (April)	2016 (October)
6	AOF - Children - 8 years postpartum	Questionnaires		2017 (February)	2019 (October)
7	AOF - Children - COVID-19 questionnaire 1	Questionnaires		2020 (July)	2020 (August)
8	AOF - Children - COVID-19 questionnaire 2	Questionnaires		2021 (March)	2021 (April)
9	AOF - Children - COVID-19 questionnaire 3	Questionnaires		2021 (November)	2022 (January)
10	AOF - Children - 12-14 years postpartum	Questionnaires Physical measures		2023 (January)	2023 (July)

Participating Studies

Acronym	Name	Study design	Countries

Harmonization Initiatives Included

Acronym	Name

Datasets

Search Variables

Name	Data Collection Events	Variables

Variables Content Summary

Areas of Information Collected per per Population and Data Collection Event

Networks

Acronym	Name	Harmonization Initiatives	Individual Studies

Last Update: 2024-06-03T04:40:59.704

All Our Families

Overview

General Design

Access

Marker Papers

Documents

Timeline

Populations

Selection Criteria

Sources of Recruitment

Sample Size

Documents

Data Collection Events

Selection Criteria

Sources of Recruitment

Sample Size

Documents

Data Collection Events

Participating Studies

Harmonization Initiatives Included

Datasets

Areas of Information Collected

Variables Content Summary

Areas of Information Collected

Areas of Information Collected per per Population and Data Collection Event

Networks

All Our Families

Overview

Suzanne Tough

Sheila McDonald

Katie Chaput

Susan Graham

Sheri Madigan

Donna Slater

Suzanne Tough

General Design

Access

Marker Papers

Documents

Timeline

Populations

AOF - Mothers - 24 weeks

AOF - Mothers - 36 weeks

AOF - Mothers - Birth

AOF - Mothers - 4 months postpartum

AOF - Mothers - 1 year postpartum

AOF - Mothers - 2 years postpartum

AOF - Mothers - 3 years postpartum

AOF - Mothers - Flood questionnaire

AOF - Mothers - 5 years postpartum

AOF - Mothers - 8 years postpartum

AOF - Mothers - COVID-19 questionnaire 1

AOF - Mothers - COVID-19 questionnaire 2

AOF - Mothers - COVID-19 questionnaire 3

AOF - Mothers - 12-14 years postpartum

AOF - Children - Birth

AOF - Children - 4 months postpartum

AOF - Children - 1 year postpartum

AOF - Children - 2 years postpartum

AOF - Children - 3 years postpartum

AOF - Children - 5 years postpartum

AOF - Children - 8 years postpartum

AOF - Children - COVID-19 questionnaire 1

AOF - Children - COVID-19 questionnaire 2

AOF - Children - COVID-19 questionnaire 3

AOF - Children - 12-14 years postpartum

Selection Criteria

Sources of Recruitment

Sample Size

Documents

Data Collection Events

Selection Criteria

Sources of Recruitment

Sample Size

Documents

Data Collection Events

Participating Studies

Harmonization Initiatives Included

Datasets

Areas of Information Collected

Variables Content Summary

Areas of Information Collected

Areas of Information Collected per per Population and Data Collection Event

Networks