Alberta Pregnancy Outcomes and Nutrition
The objectives of APrON are to:
- Examine the associations between maternal prenatal nutritional intake and status and mothers' and children's mental health and children's neurodevelopment;
- Investigate the risk factors associated with maternal and paternal perinatal mood, and the impact of maternal and paternal perinatal mood on pregnancy and birth outcomes, as well as children's mental health and neurodevelopment;
- Establish a DNA biobank that could be used to examine the influence of genomics on children's mental health and neurodevelopment.
Overview
- Acronym
- APrON
- Website
- APrON
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2009 -
- General Information on Follow Up (profile, frequency)
-
Women had their first visit in either their first or second trimester prior to 27 weeks gestation. Women were seen again in the research lab in each remaining trimester and at 3 months postpartum with their babies. Questionnaires were given to mothers approximately 6, 12, 24 and 36 months after delivery.
- Recruitment Target
-
- Families
- Number of Participants
- 5,841
- Number of Participants with Biological Samples
- 5,175
- Supplementary information about number of participants
-
Mothers: 2189 participants
Partners: 1483 participants
Children: 2169 participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
- On the study website : https://apronstudy.ca/
- By contacting the study representative: Andrea Deane (Cumming School of Medicine, University of Calgary)
Sector of research
| Possible Access to Data | Possible Access to Biosamples | |
| Investigators from the public sector | ||
| Investigators from the private sector | ||
| Investigators from not-for-profit organization |
Transfer
| Possible Access to Data | Possible Access to Biosamples | |
| Can leave the study facility | ||
| Can leave the country |
In order for requesting researchers to receive APrON data, all data requests must be reviewed and approved by a Principal Investigator; all data requests must be made in agreement with the researcher’s supervisor (if applicable); all data must be anonymized by the study team; and all researchers must sign a confidentiality agreement to not share the data with anyone else who was not approved in the request.
Cost
| Possible Access to Data | Variable Cost |
| Possible Access to Biosamples | Variable Cost |
We charge the amount of time it takes our staff to fill the request.
Cost reduction for co-analyses
| Possible Access to Data | |
| Possible Access to Biosamples |
Marker Paper
Kaplan BJ, Giesbrecht GF, Leung BM, Field CJ, Dewey D, Bell RC, Manca DP, O'Beirne M, Johnston DW, Pop VJ, Singhal N, Gagnon L, Bernier FP, Eliasziw M, McCargar LJ, Kooistra L, Farmer A, Cantell M, Goonewardene L, Casey LM, Letourneau N, Martin JW; APrON Study Team. The Alberta Pregnancy Outcomes and Nutrition (APrON) cohort study: rationale and methods. Maternal and Child Nutrition. 2014 Jan;10(1):44-60.
PUBMED 22805165Timeline
Populations
APrON - Mothers
The population is composed of pregnant women aged 16 years or older, with a gestational age of less than 27 weeks, who lived in the metropolitan areas of Calgary and Edmonton in Alberta, Canada.
Selection Criteria
- Gender
-
Women only
- Minimum age
-
16
- Pregnant Women
-
- First trimester
- Second trimester
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- Territory
- Metropolitan areas of Calgary and Edmonton in Alberta
- Other Criteria
- Gestational age of less than 27 weeks
Sources of Recruitment
- General Population
-
- Volunteer enrolment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Calgary recruitment included stationing research assistants in waiting rooms of high-volume maternity care and ultrasound clinics. Edmonton recruitment was organized through a collaborative process with the Women and Children’s Health Research Institute at the University of Alberta, distributing information across the city’s many clinics. Other recruitment strategies used in both cities included posters and media advertising.
Sample Size
- Number of Participants
- 2,189
- Number of Participants with Biological Samples
- 2,041
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | APrON - Mothers - First trimester |
|
|
2009 (January) | 2012 (June) |
| 1 | APrON - Mothers - Second trimester |
|
|
2009 (May) | 2012 (September) |
| 2 | APrON - Mothers - Third trimester |
|
|
2009 (July) | 2012 (November) |
| 3 | APrON - Mothers - Birth |
|
2009 (August) | 2013 (February) | |
| 4 | APrON - Mothers - 12 weeks postpartum |
|
|
2009 (November) | 2013 (May) |
| 5 | APrON - Mothers - 24 weeks postpartum |
|
2010 (February) | 2013 (November) | |
| 6 | APrON - Mothers - 12 months postpartum |
|
2010 (September) | 2014 (June) | |
| 7 | APrON - Mothers - 24 months postpartum |
|
2011 (August) | 2015 (February) | |
| 8 | APrON - Mothers - 3 years postpartum |
|
2012 (September) | 2016 (May) | |
| 9 | APrON - Mothers - 5 years postpartum |
|
2014 (August) | 2018 (May) |
APrON - Partners
The population is composed of the partners of the women included in the study.
Selection Criteria
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- Territory
- Metropolitan areas of Calgary and Edmonton in Alberta
Sources of Recruitment
- Specific Population
-
- Other specific population : Partners of the pregnant women already recruited.
Sample Size
- Number of Participants
- 1,483
- Number of Participants with Biological Samples
- 1,343
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | APrON - Partners - Second trimester |
|
|
2009 (April) | 2012 (December) |
| 1 | APrON - Partners - 12 weeks postpartum |
|
2009 (November) | 2013 (May) | |
| 2 | APrON - Partners - 5 years postpartum |
|
2014 (August) | 2018 (May) |
APrON - Children
The population includes the babies of the women already recruited in the study.
Selection Criteria
- Newborns
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- Territory
- Metropolitan areas of Calgary and Edmonton in Alberta
Sources of Recruitment
- Specific Population
-
- Other specific population : Newborn children of the women enrolled in the study.
Sample Size
- Number of Participants
- 2,169
- Number of Participants with Biological Samples
- 1,791
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | APrON - Children - Birth |
|
2009 (August) | 2013 (May) | |
| 1 | APrON - Children - 12 weeks postpartum |
|
|
2009 (November) | 2013 (May) |
| 2 | APrON - Children - 24 weeks postpartum |
|
2010 (February) | 2013 (August) | |
| 3 | APrON - Children - 12 months postpartum |
|
2010 (September) | 2014 (February) | |
| 4 | APrON - Children - 24 months postpartum |
|
2011 (August) | 2015 (February) | |
| 5 | APrON - Children - 3 years postpartum |
|
2012 (September) | 2016 (May) | |
| 6 | APrON - Children - 5 years postpartum |
|
2014 (August) | 2018 (May) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2021-04-29T17:39:30.305