Biobanque Québécoise de la COVID-19
The Biobanque québécoise de la COVID-19 (BQC19) is a pan-provincial initiative that collects, stores and shares data and blood samples from COVID-19 patients, both severe and non-severe cases and control cases, in an effort to respond effectively to the public health challenges posed by the pandemic.
The objectives of the Biobanque Québécoise de la COVID-19 are:
* To support the institutions of the health and social services network (HSSN) by facilitating the supervision and common resource management of the unique biological material and data stored in the BQC19 to make them accessible for research on COVID-19 and related diseases.
* To ensure provincial coordination and identification of the expected standards of various banking infrastructures established in the HSSN institutions and federated to constitute the BQC19.
* To support efforts to discover and develop new biomarkers of disease sensitivity and progression, therapies and vaccines that are new or re-directed to address COVID-19, as well as any research effort related to the prevention, treatment, and epidemiological and population management of COVID-19.
* To encourage health research and precision medicine on COVID-19.
Overview
- Acronym
- BQC19
- Website
- BQC19
- Investigators
-
- Contacts
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General Design
- Study design
- Case-control
- Start - End Year
- 2020 -
- General Information on Follow Up (profile, frequency)
-
After first hospitalization, inpatients (positive and control cases) are followed-up at 7 days post hospitalization. Starting June 2020, inpatients are followed-up at 14 and 30 days post hospitalization. Inpatients are also followed-up at 30, 90, 180, 365, 540 and 730 days post hospitalization discharge.
Outpatients are not followed in the acute phase of COVID (0-14 days), follow-ups begin approximately 30 days following the date of the diagnostic test by PCR tests (or other). They are also followed-up 90, 180, 365, 540 and 730 days post a SARS-CoV-2 positive test result.
Some sites have continued to follow up on their own research funds and these follow-ups are entered into the BQC19 databases.Follow-up dates are approximate and follow-up visits may be done consecutively for pediatric patients (since there were differences in the hospitalizations of the pediatric cases, it is possible that the 5 visits were also consecutive days).
For inpatients and outpatients, starting February 2023, the follow-ups at 365 and 730 days is spread over 5 sites only.
- Recruitment Target
-
- Individuals
- Number of Participants
- 6,273
- Number of Participants with Biological Samples
- 5,263
- Supplementary information about number of participants
-
* As of August 2023, 6273 participants (including 83 pregnant women) have been enrolled. * 3 inpatient participants have an inderteminate diagnosis for COVID-19 or still have there information entry in progress. * 2 outpatient participants have an inderteminate diagnosis for COVID-19 or still have there information entry in progress.
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Papers
Tremblay K, Rousseau S, Zawati MH, et al. The Biobanque québécoise de la COVID-19 (BQC19)-A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories. PLoS One. 2021 May 19;16(5):e0245031. doi: 10.1371/journal.pone.0245031.
PUBMED 34010280Timeline
Populations
BQC19 - Inpatient positive cases
The population is composed of patients (including pregnant women and pediatric patients) who have been hospitalized with moderate to severe illness and who underwent a PCR test for SARS-CoV-2 with a positive result.
Selection Criteria
- Countries
-
- Canada
- Canadian Provinces
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- Quebec
- Health Status
-
- Participants are included if they were hospitalized with a moderate or severe illness and who underwent a PCR test for SARS-CoV-2 with a positive result.
- Other Criteria
- Inclusion criteria for adults and children: * Patients who were tested for COVID-19 at one of the participating institutions of the BQC19. Inclusion criteria for adults only: * Adults capable of consent to research. * Adults rendered incapable of consent to research due to COVID-19 (sudden and temporary incapacity), if represented by an agent, guardian or curator. * Adults incapable of consent to research due to a condition other than COVID-19, if represented by an agent, guardian or curator.
Sources of Recruitment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Participants are recruited during a hospital stay in a COVID unit or in intensive care. Recruitement of adult patients ended on February 14th 2023.
Sample Size
- Number of Participants
- 2,541
- Number of Participants with Biological Samples
- 2,541
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | BCQ19 - Inpatient positive cases - Enrollment |
|
|
2020 (April) | Ongoing |
| 1 | BCQ19 - Inpatient positive cases - 2 days post hospitalization |
|
|
2020 (April) | 2023 (February) |
| 2 | BCQ19 - Inpatient positive cases - 7 days post hospitalization |
|
|
2020 (April) | 2023 (February) |
| 3 | BCQ19 - Inpatient positive cases - 14 days post hospitalization |
|
|
2020 (June) | 2023 (February) |
| 4 | BCQ19 - Inpatient positive cases - 30 days post hospitalization |
|
|
2020 (June) | 2023 (February) |
| 5 | BCQ19 - Inpatient positive cases - Discharge |
|
2020 (April) | 2023 (February) | |
| 6 | BCQ19 - Inpatient positive cases - 30 days post discharge |
|
|
2020 (May) | 2023 (February) |
| 7 | BCQ19 - Inpatient positive cases - 90 days post discharge |
|
|
2020 (July) | 2023 (February) |
| 8 | BCQ19 - Inpatient positive cases - 180 days post discharge |
|
|
2020 (August) | 2023 (February) |
| 9 | BCQ19 - Inpatient positive cases - 365 days post discharge |
|
|
2021 (February) | Ongoing |
| 10 | BCQ19 - Inpatient positive cases - 540 days post discharge |
|
|
2021 (August) | 2023 (February) |
| 11 | BCQ19 - Inpatient positive cases - 730 days post discharge |
|
2022 (February) | Ongoing |
BQC19 - Inpatient controls
The population is composed of patients (including pregnant women and pediatric patients) who have been hospitalized with moderate to severe illness and who underwent a PCR test for SARS-CoV-2 with a negative result.
Selection Criteria
- Countries
-
- Canada
- Canadian Provinces
-
- Quebec
- Health Status
-
- Participants are included if they were hospitalized with a moderate or severe illness and who underwent a PCR test for SARS-CoV-2 with a negative result.
- Other Criteria
- Inclusion criteria for adults and children: * Patients who were tested for COVID-19 at one of the participating institutions of the BQC19. Inclusion criteria for adults only: * Adults capable of consent to research. * Adults rendered incapable of consent to research due to COVID-19 (sudden and temporary incapacity), if represented by an agent, guardian or curator. * Adults incapable of consent to research due to a condition other than COVID-19, if represented by an agent, guardian or curator.
- Supplementary Information about selection criteria
-
Recruitement of adult patients ended on February 14th 2023.
Sources of Recruitment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Participants are recruited during a hospital stay in a COVID unit or in intensive care. Recruitement of adult patients ended on February 14th 2023.
Sample Size
- Number of Participants
- 911
- Number of Participants with Biological Samples
- 911
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | BCQ19 - Inpatient controls - Enrollment |
|
|
2020 (May) | Ongoing |
| 1 | BCQ19 - Inpatient controls - 2 days post hospitalization |
|
|
2020 (May) | 2023 (February) |
| 2 | BCQ19 - Inpatient controls - 7 days post hospitalization |
|
|
2020 (May) | 2023 (February) |
| 3 | BCQ19 - Inpatient controls - 14 days post hospitalization |
|
|
2020 (June) | 2023 (February) |
| 4 | BCQ19 - Inpatient controls - 30 days post hospitalization |
|
|
2020 (June) | 2023 (February) |
| 5 | BCQ19 - Inpatient controls - Discharge |
|
2020 (May) | Ongoing | |
| 6 | BCQ19 - Inpatient controls - 30 days post discharge |
|
|
2020 (May) | 2023 (February) |
| 7 | BCQ19 - Inpatient controls - 90 days post discharge |
|
|
2020 (July) | 2023 (February) |
| 8 | BCQ19 - Inpatient controls - 180 days post discharge |
|
|
2020 (August) | 2023 (February) |
| 9 | BCQ19 - Inpatient controls - 365 days post discharge |
|
|
2021 (January) | Ongoing |
| 10 | BCQ19 - Inpatient controls - 540 days post discharge |
|
|
2021 (August) | 2023 (February) |
| 11 | BCQ19 - Inpatient controls - 730 days post discharge |
|
2022 (March) | Ongoing |
BQC19 - Outpatient positive cases
The population is composed of adult participants (including pregnant women) with mild illness or who are asymptomatic and who underwent a PCR test for SARS-CoV-2 with a positive result.
Selection Criteria
- Minimum age
-
18
- Countries
-
- Canada
- Canadian Provinces
-
- Quebec
- Health Status
-
- Participants with asymptomatic and mild symptoms who underwent a PCR test for SARS-CoV-2 with a positive result are included.
- Other Criteria
- Inclusion: * Patients who were tested for COVID-19 at one of the participating institutions of the BQC19. * Adults capable of consent to research. * Adults rendered incapable of consent to research due to COVID-19 (sudden and temporary incapacity), if represented by an agent, guardian or curator. * Adults incapable of consent to research due to a condition other than COVID-19, if represented by an agent, guardian or curator. Due to a decrease in PCR screenings, the study stopped requesting for mandatory PCR test since November 2022.
Sources of Recruitment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Participants are recruited in outpatient clinics or post-COVID clinics. Recruitement ended on February 14th 2023.
Sample Size
- Number of Participants
- 2,638
- Number of Participants with Biological Samples
- 2,638
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | BCQ19 - Outpatient positive cases - Enrollment |
|
2020 (April) | 2023 (February) | |
| 2 | BCQ19 - Outpatient positive cases - 30 days post diagnosis |
|
|
2020 (May) | 2023 (February) |
| 3 | BCQ19 - Outpatient positive cases - 90 days post diagnosis |
|
|
2020 (July) | 2023 (February) |
| 4 | BCQ19 - Outpatient positive cases - 180 days post diagnosis |
|
|
2020 (August) | 2023 (February) |
| 5 | BCQ19 - Outpatient positive cases - 365 days post diagnosis |
|
|
2021 (March) | Ongoing |
| 6 | BCQ19 - Outpatient positive cases - 540 days post diagnosis |
|
|
2021 (August) | 2023 (February) |
| 7 | BCQ19 - Outpatient positive cases - 730 days post diagnosis |
|
2022 (March) | Ongoing |
BQC19 - Outpatient controls
The population is composed of adult participants (including pregnant women) with mild illness or who are asymptomatic and who underwent a PCR test for SARS-CoV-2 with a negative result.
Selection Criteria
- Minimum age
-
18
- Countries
-
- Canada
- Canadian Provinces
-
- Quebec
- Health Status
-
- Participants with asymptomatic and mild symptoms who underwent a PCR test for SARS-CoV-2 with a negative result are included.
- Other Criteria
- Inclusion: * Patients who were tested for COVID-19 at one of the participating institutions of the BQC19. * Adults capable of consent to research. * Adults rendered incapable of consent to research due to COVID-19 (sudden and temporary incapacity), if represented by an agent, guardian or curator. * Adults incapable of consent to research due to a condition other than COVID-19, if represented by an agent, guardian or curator. Due to a decrease in PCR screenings, the study stopped requesting for mandatory PCR test since November 2022.
Sources of Recruitment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Participants are recruited in outpatient clinics or post-COVID clinics. Recruitement ended on February 14th 2023.
Sample Size
- Number of Participants
- 136
- Number of Participants with Biological Samples
- 136
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | BCQ19 - Outpatient controls - Enrollment |
|
2020 (March) | 2023 (February) | |
| 2 | BCQ19 - Outpatient controls - 30 days post diagnosis |
|
|
2020 (May) | 2023 (February) |
| 3 | BCQ19 - Outpatient controls - 90 days post diagnosis |
|
|
2020 (July) | 2023 (February) |
| 4 | BCQ19 - Outpatient controls - 180 days post diagnosis |
|
|
2020 (August) | 2023 (February) |
| 5 | BCQ19 - Outpatient controls - 365 days post diagnosis |
|
|
2021 (March) | Ongoing |
| 6 | BCQ19 - Outpatient controls - 540 days post diagnosis |
|
|
2021 (August) | 2023 (February) |
| 7 | BCQ19 - Outpatient controls - 730 days post diagnosis |
|
2022 (March) | Ongoing |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2025-08-13T10:42:19.703