Canadian Alliance for Healthy Hearts and Minds Cohort Study
The objectives of the study are:
* To understand the role of socio-environmental and contextual factors (such as societal structure, activity, nutrition, social and tobacco environments, and access to health services) on cardiovascular (CV) risk factors, subclinical disease, and clinical CV events at the individual and population levels. This will include investigating the impact of contextual factors on geographic variation in CV disease (i.e. rural vs. urban, and east to west gradient), and their relative impact compared to individual level factors.
* To characterize the unique patterns of contextual factors as well as acculturation, cultural continuity, and migration experience as related to individual CV risk factors, health service utilization, and clinical outcomes among high risk ethnic groups including South Asians, Chinese, African origin from across Canada.
* To identify markers for early sub-clinical dysfunction in the brain, vessels, heart and abdomen using magnetic resonance imaging, and to investigate the associations with contextual and individual determinants of these markers, as well as to assess the predictive value of novel markers of sub-clinical dysfunction on the development of clinical CV events.
Overview
- Acronym
- CAHHM
- Website
- CAHHM
- Investigators
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- Contacts
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General Design
- Study design
- Cohort
- Start - End Year
- 2013 - 2021
- General Information on Follow Up (profile, frequency)
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All participants are assessed at enrollment.
- Recruitment Target
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- Individuals
- Number of Participants
- 8,258
- Number of Participants with Biological Samples
- 5,392
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
Marker Papers
Anand SS, Tu JV, Awadalla P et. al. Rationale, design, and methods for Canadian alliance for healthy hearts and minds cohort study – a Pan Canadian cohort study. BMC Public Health, 2016; 16:650.
PUBMED 27464510Timeline
Population
CAHHM population
The population is composed of men and women aged 35-69 years, recruited from all participating cohorts of the Canadian Partnership for Tomorrow Project (CanPath), the Prospective Urban Rural Evaluation (PURE)-Canada cohort, and the Montreal Heart Institute (MHI) Biobank.
Selection Criteria
- Minimum age
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35
- Maximum age
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69
- Countries
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- Canada
- Canadian Provinces
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- Alberta
- British Columbia
- New Brunswick
- Newfoundland and Labrador
- Nova Scotia
- Ontario
- Prince Edward Island
- Quebec
- Territory
- Metropolitan Montreal and Quebec City, Greater Toronto Area, London, Hamilton, Ottawa, Metro Vancouver, Halifax and surrounding area, Calgary, Edmonton
- Other Criteria
- Exclusion criteria: * Participant is claustrophobic and/or is known to suffer from moderate to severe anxiety during MRI scans or similar procedures. * Participant is obese and/or exceeds equipment weight limit and/or circumference of the MRI portal at time of screening. * Participant has a metallic implant or another foreign body which is not compatible with Magnetic Resonance Imaging (MRI) (eg pacemakers, defibrillator, vascular clips, drug pumps, implant(s), or any other foreign bodies, extensive tattoo covering a large part of their chest or head). * Female participants that are or may be pregnant (confirmed or uncertain). * Received an MRI contrast agent within 72 h prior to the MRI scan. * Participants who live on Canadian aboriginal reserves.
Sources of Recruitment
- General Population
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- Selected sample
- Participants from Existing Studies
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- Canadian Partnership for Tomorrow Project
Prospective Urban Rural Evaluation (PURE)-Canada cohort
Montreal Heart Institute (MHI) Biobank
- Canadian Partnership for Tomorrow Project
Sample Size
- Number of Participants
- 8,258
- Number of Participants with Biological Samples
- 4,333
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CAHHM - Enrollment |
|
|
2013 (December) | 2018 (March) |
Participating Studies
| Acronym | Name | Study design | Countries |
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Harmonization Initiatives Included
| Acronym | Name |
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Datasets
| Name | Data Collection Events | Variables |
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Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
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Last Update: 2024-02-26T16:57:53.408