Canadian Multicentre Osteoporosis Study

The overarching objectives of CaMos are: - to examine the development and demographics of osteoporosis; - to identify risk factors for osteoporotic fractures (e.g. genetic risk factors, calcium and vitamin D intake and serum levels, proton pump inhibitors, physical activities) and their associations with BMD, fractures, and/or mortality; and - to assess outcomes of osteoporosis and treatment.

Overview

Acronym
CaMos
Website
CaMos
Investigators
Dr. David Goltzman
McGill University
Dr. Nancy Kreiger
University of Toronto
Contacts
Claudie Berger
McGill University

General Design

Study design
Cohort
Start - End Year
1995 - 2018
General Information on Follow Up (profile, frequency)

Participants were followed annually by postal questionnaire to obtain medication and fracture history. Details regarding reported fractures were obtained through a telephone interview. The data collection at Year 3 (participants aged 40-60 years), Year 5 (all participants), Year 10 (all participants) and Year 16 (women aged 60-75 years) follow-ups included an extensive interviewer-administered questionnaire and a clinical assessment (bone mineral density, X-rays, ultrasounds, height and weight measurements). Participants not selected to do a full interview at Year 3 and 16 follow-ups, received a short postal follow-up questionnaire on fractures. 

Recruitment Target
  • Individuals
Number of Participants
10,424
Number of Participants with Biological Samples
No Limit
Supplementary information about number of participants

6539 women and 2884 men aged 25 years and older; 527 young women and 474 young men aged 16-24 years.

Supplementary Information

The Canadian Multicentre Osteoporosis Study (CaMos) is an ongoing population-based longitudinal study of community-dwelling adults (ages 25 years and older) recruited from 1995 to 1997. Between 2004 and 2006, a cohort of young women and men 16-24 years old was also recruited. Both cohorts have been drawn from a random population-based sample of non-institutionalized men and women living within 50 km of one of nine Canadian cities (St John’s, Halifax, Quebec City, Kingston, Toronto, Hamilton, Saskatoon, Calgary and Vancouver), referred to as centres, encompassing roughly 40% of the Canadian population. Households were randomly selected from residential phone numbers; participants were then selected from households by an age-stratified protocol. In the adult cohort (ages 25 years and older), this protocol weighted to older adults with two thirds women.

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other

All CaMos data are accessible to external researchers as long as they collaborate with one of the CaMos investigators.

Marker Paper

Kreiger N, Tenenhouse A, Joseph L, Mackenzie T, Poliquin S, Brown JP, Prior JC, Rittmaster RS. (1999) The Canadian Multicentre Osteoporosis Study (CaMos): Background, rationale, methods. Can J Aging 18(3):376-87

Timeline

Populations

CaMos - Adult Cohort (25 years and older)

The adult cohort includes non-institutionalized men and women aged 25 years or older living within 50 km of one of nine Canadian cities.

Selection Criteria

Minimum age
25
Countries
  • Canada
Canadian Provinces
  • Alberta
  • British Columbia
  • Newfoundland and Labrador
  • Nova Scotia
  • Ontario
  • Quebec
  • Saskatchewan
Territory

Living within 50 km of one of nine Canadian cities (St John’s, Halifax, Quebec City, Kingston, Toronto, Hamilton, Saskatoon, Calgary and Vancouver)

Other Criteria

Random selection of non-institutionalized adults

Sources of Recruitment

General Population
  • Selected sample

Sample Size

Number of Participants
9,423
Supplementary information about number of participants

6539 women and 2884 men

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 CaMos - Adult Cohort - Baseline
  • Questionnaires
  • Physical measures
  • Biosamples
  • Blood
  • Urine
1995 (July) 1997 (September)
1 CaMos - Adult Cohort - Year 1 Follow-up
  • Questionnaires
1996 (August) 1998 (December)
2 CaMos - Adult Cohort - Year 2 Follow-up
  • Questionnaires
1997 (July) 2000 (February)
3 CaMos - Adult Cohort - Year 3 Follow-up
  • Questionnaires
  • Physical measures
1998 (July) 2001 (January)
4 CaMos - Adult Cohort - Year 4 Follow-up
  • Questionnaires
1999 (January) 2001 (December)
5 CaMos - Adult Cohort - Year 5 Follow-up
  • Questionnaires
  • Physical measures
  • Biosamples
  • Blood
  • Urine
2001 (December) 2004 (January)
6 CaMos - Adult Cohort - Year 6 Follow-up
  • Questionnaires
2002 (August) 2004 (December)
7 CaMos - Adult Cohort - Year 7 Follow-up
  • Questionnaires
2003 (November) 2006 (February)
8 CaMos - Adult Cohort - Year 8 Follow-up
  • Questionnaires
2004 (October) 2007 (January)
9 CaMos - Adult Cohort - Year 9 Follow-up
  • Questionnaires
2006 (September) 2009 (January)
10 CaMos - Adult Cohort - Year 10 Follow-up
  • Questionnaires
  • Physical measures
  • Biosamples
  • Blood
  • Urine
2007 (July) 2010 (January)
11 CaMos - Adult Cohort - Year 11 Follow-up
  • Questionnaires
2008 (September) 2011 (April)
12 CaMos - Adult Cohort - Year 12 Follow-up
  • Questionnaires
2009 (August) 2011 (November)
13 CaMos - Adult Cohort - Year 13 Follow-up
  • Questionnaires
2011 (March) 2012 (September)
14 CaMos - Adult Cohort - Year 14 Follow-up
  • Questionnaires
2012 (January) 2013 (December)
15 CaMos - Adult Cohort - Year 15 Follow-up
  • Questionnaires
2013 (January) 2013 (December)
16 CaMos - Adult Cohort - Year 16 Follow-up
  • Questionnaires
  • Physical measures
  • Biosamples
  • Blood
  • Urine
2014 (January) 2014 (December)
17 CaMos - Adult Cohort - Year 17 Follow-up
  • Questionnaires
2015 (January) 2015 (December)
18 CaMos - Adult Cohort - Year 18 Follow-up
  • Questionnaires
2016 (January) 2016 (December)
19 CaMos - Adult Cohort - Year 19 Follow-up
  • Questionnaires
2017 (January) 2017 (December)
20 CaMos - Adult Cohort - Year 20 Follow-up
  • Questionnaires
2018 (January) 2018 (December)
CaMos - Youth Cohort (16-24 years old)

The youth cohort includes young men and women aged 16-24 years living within 50 km of one of nine Canadian cities. The same recruitment method as with the adult cohort was used. However, there were no oversampling.

Selection Criteria

Minimum age
16
Maximum age
24
Countries
  • Canada
Canadian Provinces
  • Alberta
  • British Columbia
  • Newfoundland and Labrador
  • Nova Scotia
  • Ontario
  • Quebec
  • Saskatchewan
Territory

Living within 50 km of one of nine Canadian cities (St John’s, Halifax, Quebec City, Kingston, Toronto, Hamilton, Saskatoon, Calgary and Vancouver)

Other Criteria

Random selection through phone directory

Sources of Recruitment

General Population
  • Selected sample

Sample Size

Number of Participants
1,001
Supplementary information about number of participants

527 women and 474 men

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 CaMos - Youth Cohort - Baseline
  • Questionnaires
  • Physical measures
  • Biosamples
  • Blood
  • Saliva
  • Urine
2004 (July) 2006 (June)
1 CaMos - Youth Cohort - Year 1 Follow-up
  • Questionnaires
  • Biosamples
  • Blood
  • Urine
2005 (September) 2008 (February)
2 CaMos - Youth Cohort - Year 2 Follow-up
  • Questionnaires
  • Physical measures
  • Biosamples
  • Blood
  • Urine
2006 (August) 2008 (December)

Participating Studies

Acronym Name Study design Countries

Harmonization Initiatives Included

Acronym Name

Datasets

Name Data Collection Events Variables

Areas of Information Collected

Socio-demographic and economic characteristics
Death
Lifestyle and behaviours
Physical measures and assessments
Birth, pregnancy and reproductive health history
Laboratory measures
Perception of health, quality of life, development and functional limitations
Cognition, personality and psychological measures and assessments
Diseases
Life events, life plans, beliefs and values
Symptoms and signs
Preschool, school and work life
Medication and supplements
Social environment and relationships
Non-pharmacological interventions
Physical environment
Health and community care services utilization
Administrative information

Variables Content Summary

Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected

Networks

Acronym Name Harmonization Initiatives Individual Studies
Last Update: 2021-04-29T17:54:10.215