Canadian Cohort of Obstructive Lung Disease
The Canadian Cohort Obstructive Lung Disease (CanCOLD) study is a well-designed longitudinal study following ~1,500 participants in 9 cities and 6 Canadian provinces since 2009.
CanCOLD’s main objective is to identify potentially modifiable factors beyond tobacco smoking that impact COPD development and disease progression.
Secondary objectives include:
1. Identifying combinations of disease and patient attributes (clinical, physiological, morphological, biological) that differentiate individuals with COPD (any, mild to moderate/early disease) as they relate to relevant outcomes (burden of symptoms/health-related quality of life, disease progression, health service use or death), and
2. Evaluating past and current clinical practice for the care of mild and moderate COPD.
Overview
- Acronym
- CanCOLD
- Website
- CanCOLD
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2009 -
- General Information on Follow Up (profile, frequency)
-
Participants were followed-up every 18 months (in-site) after the baseline visit and quarterly (via telephone) starting in July 2012.
- Recruitment Target
-
- Individuals
- Number of Participants
- 1,561
- Number of Participants with Biological Samples
- 1,386
- Supplementary information about number of participants
-
COPD moderate-severe: 346 participants
COPD mild: 486 participants
At risk: 422 participants
Healthy controls: 307 participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Paper
Bourbeau J, Tan WC, Benedetti A, et al., Canadian Cohort Obstructive Lung Disease (CanCOLD): Fulfilling the Need for Longitudinal Observational Studies in COPD. COPD. 2012 Mar 20.
PUBMED 22433011Timeline
Populations
CanCOLD - COPD moderate-severe
The population is composed of non-institutionalized adults, men and women, aged 40 and more who suffered from moderate to severe COPD (GOLD 2-4).
Selection Criteria
- Minimum age
-
40
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Nova Scotia
- Ontario
- Quebec
- Saskatchewan
- Territory
- Montréal, Vancouver, Calgary, Halifax, Toronto, Ottawa, Kingston, Québec, Saskatoon
- Health Status
-
- With moderate to severe COPD (GOLD 2-4)
- Other Criteria
- The subjects have to live near one of the study site
Sources of Recruitment
- General Population
-
- Random digit dialing
- Participants from Existing Studies
-
- The Canadian Obstructive Lung Disease (COLD) prevalence study
Sample Size
- Number of Participants
- 346
- Number of Participants with Biological Samples
- 308
Data Collection Events
CanCOLD - COPD mild
The population is composed of non-institutionalized adults, men and women, aged 40 and more who suffered mild COPD (GOLD 1).
Selection Criteria
- Minimum age
-
40
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Nova Scotia
- Ontario
- Quebec
- Saskatchewan
- Territory
- Montréal, Vancouver, Calgary, Halifax, Toronto, Ottawa, Kingston, Québec, Saskatoon
- Health Status
-
- With mild COPD (GOLD 1)
- Other Criteria
- The subjects have to live near one of the study site
Sources of Recruitment
- General Population
-
- Random digit dialing
- Participants from Existing Studies
-
- The Canadian Obstructive Lung Disease (COLD) prevalence study
Sample Size
- Number of Participants
- 486
- Number of Participants with Biological Samples
- 433
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CanCOLD - COPD mild - Baseline |
|
|
2009 (November) | 2015 (August) |
| 1 | CanCOLD - COPD mild - 18 months |
|
|
2011 (June) | 2015 (November) |
| 2 | CanCOLD - COPD mild - Quarterly follow-up 1 |
|
2012 (July) | 2012 (July) | |
| 3 | CanCOLD - COPD mild - Quarterly follow-up 2 |
|
2012 (October) | 2012 (October) | |
| 4 | CanCOLD - COPD mild - 36 months |
|
|
2013 (January) | 2019 (August) |
| 5 | CanCOLD - COPD mild - Quarterly follow-up 3 |
|
2013 (January) | 2013 (January) | |
| 6 | CanCOLD - COPD mild - Quarterly follow-up 4 |
|
2013 (April) | 2013 (April) | |
| 7 | CanCOLD - COPD mild - Quarterly follow-up 5 |
|
2013 (July) | 2013 (July) | |
| 8 | CanCOLD - COPD mild - Quarterly follow-up 6 |
|
2013 (October) | 2013 (October) | |
| 9 | CanCOLD - COPD mild - Quarterly follow-up 7 |
|
2014 (January) | 2014 (January) | |
| 10 | CanCOLD - COPD mild - Quarterly follow-up 8 |
|
2014 (April) | 2014 (April) | |
| 11 | CanCOLD - COPD mild - Quarterly follow-up 9 |
|
2014 (July) | 2014 (July) | |
| 12 | CanCOLD - COPD mild - Quarterly follow-up 10 |
|
2014 (October) | 2014 (October) | |
| 13 | CanCOLD - COPD mild - Quarterly follow-up 11 |
|
2015 (January) | 2015 (January) | |
| 14 | CanCOLD - COPD mild - Quarterly follow-up 12 |
|
2015 (April) | 2015 (April) | |
| 15 | CanCOLD - COPD mild - Quarterly follow-up 13 |
|
2015 (July) | 2015 (July) | |
| 16 | CanCOLD - COPD mild - Quarterly follow-up 14 |
|
2015 (October) | 2015 (October) | |
| 17 | CanCOLD - COPD mild - Quarterly follow-up 15 |
|
2016 (January) | 2016 (January) | |
| 18 | CanCOLD - COPD mild - Quarterly follow-up 16 |
|
2016 (April) | 2016 (April) | |
| 19 | CanCOLD - COPD mild - Quarterly follow-up 17 |
|
2016 (July) | 2016 (July) | |
| 20 | CanCOLD - COPD mild - Quarterly follow-up 18 |
|
2016 (October) | 2016 (October) | |
| 21 | CanCOLD - COPD mild - Quarterly follow-up 19 |
|
2017 (January) | 2017 (January) | |
| 22 | CanCOLD - COPD mild - Quarterly follow-up 20 |
|
2017 (April) | 2017 (April) | |
| 23 | CanCOLD - COPD mild - Quarterly follow-up 21 |
|
2017 (July) | 2017 (July) | |
| 24 | CanCOLD - COPD mild - Quarterly follow-up 22 |
|
2017 (October) | 2017 (October) | |
| 25 | CanCOLD - COPD mild - Quarterly follow-up 23 |
|
2018 (January) | 2018 (January) | |
| 26 | CanCOLD - COPD mild - Quarterly follow-up 24 |
|
2018 (April) | 2018 (April) | |
| 27 | CanCOLD - COPD mild - Quarterly follow-up 25 |
|
2018 (July) | 2018 (July) | |
| 28 | CanCOLD - COPD mild - Quarterly follow-up 26 |
|
2018 (October) | 2018 (October) | |
| 29 | CanCOLD - COPD mild - Quarterly follow-up 27 |
|
2019 (January) | 2019 (January) | |
| 30 | CanCOLD - COPD mild - Quarterly follow-up 28 |
|
2019 (April) | 2019 (April) | |
| 31 | CanCOLD - COPD mild - Quarterly follow-up 29 |
|
2019 (July) | 2019 (July) | |
| 32 | CanCOLD - COPD mild - Quarterly follow-up 30 |
|
2019 (October) | 2019 (October) | |
| 33 | CanCOLD - COPD mild - Quarterly follow-up 31 |
|
2020 (January) | 2020 (January) | |
| 34 | CanCOLD - COPD mild - Quarterly follow-up 32 |
|
2020 (April) | 2020 (April) | |
| 35 | CanCOLD - COPD mild - Quarterly follow-up 33 |
|
2020 (July) | 2020 (July) | |
| 36 | CanCOLD - COPD mild - Quarterly follow-up 34 |
|
2020 (October) | 2020 (October) | |
| 37 | CanCOLD - COPD mild - 54 months |
|
|
2021 | Ongoing |
| 38 | CanCOLD - COPD mild - Quarterly follow-up 35 |
|
2021 (January) | 2021 (January) | |
| 39 | CanCOLD - COPD mild - Quarterly follow-up 36 |
|
2021 (April) | 2021 (April) | |
| 40 | CanCOLD - COPD mild - Quarterly follow-up 37 |
|
2021 (July) | 2021 (July) | |
| 41 | CanCOLD - COPD mild - Quarterly follow-up 38 |
|
2021 (October) | 2021 (October) |
CanCOLD - At risk
The population is composed of non-institutionalized adults, men and women, aged 40 and more, with a normal post bronchodilator spirometry, who are ever smokers.
Selection Criteria
- Minimum age
-
40
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Nova Scotia
- Ontario
- Quebec
- Saskatchewan
- Territory
- Montréal, Vancouver, Calgary, Halifax, Toronto, Ottawa, Kingston, Québec, Saskatoon
- Health Status
-
- With normal post bronchodilator spirometry
- Other Criteria
- Ever smoker, live near one of the study site
Sources of Recruitment
- General Population
-
- Random digit dialing
- Participants from Existing Studies
-
- The Canadian Obstructive Lung Disease (COLD) prevalence study
Sample Size
- Number of Participants
- 422
- Number of Participants with Biological Samples
- 372
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CanCOLD - At risk - Baseline |
|
|
2009 (November) | 2015 (August) |
| 1 | CanCOLD - At risk - 18 months |
|
|
2011 (June) | 2015 (November) |
| 2 | CanCOLD - At risk - Quarterly follow-up 1 |
|
2012 (July) | 2012 (July) | |
| 3 | CanCOLD - At risk - Quarterly follow-up 2 |
|
2012 (October) | 2012 (October) | |
| 4 | CanCOLD - At risk - 36 months |
|
|
2013 (January) | 2019 (August) |
| 5 | CanCOLD - At risk - Quarterly follow-up 3 |
|
2013 (January) | 2013 (January) | |
| 6 | CanCOLD - At risk - Quarterly follow-up 4 |
|
2013 (April) | 2013 (April) | |
| 7 | CanCOLD - At risk - Quarterly follow-up 5 |
|
2013 (July) | 2013 (July) | |
| 8 | CanCOLD - At risk - Quarterly follow-up 6 |
|
2013 (October) | 2013 (October) | |
| 9 | CanCOLD - At risk - Quarterly follow-up 7 |
|
2014 (January) | 2014 (January) | |
| 10 | CanCOLD - At risk - Quarterly follow-up 8 |
|
2014 (April) | 2014 (April) | |
| 11 | CanCOLD - At risk - Quarterly follow-up 9 |
|
2014 (July) | 2014 (July) | |
| 12 | CanCOLD - At risk - Quarterly follow-up 10 |
|
2014 (October) | 2014 (October) | |
| 13 | CanCOLD - At risk - Quarterly follow-up 11 |
|
2015 (January) | 2015 (January) | |
| 14 | CanCOLD - At risk - Quarterly follow-up 12 |
|
2015 (April) | 2015 (April) | |
| 15 | CanCOLD - At risk - Quarterly follow-up 13 |
|
2015 (July) | 2015 (July) | |
| 16 | CanCOLD - At risk - Quarterly follow-up 14 |
|
2015 (October) | 2015 (October) | |
| 17 | CanCOLD - At risk - Quarterly follow-up 15 |
|
2016 (January) | 2016 (January) | |
| 18 | CanCOLD - At risk - Quarterly follow-up 16 |
|
2016 (April) | 2016 (April) | |
| 19 | CanCOLD - At risk - Quarterly follow-up 17 |
|
2016 (July) | 2016 (July) | |
| 20 | CanCOLD - At risk - Quarterly follow-up 18 |
|
2016 (October) | 2016 (October) | |
| 21 | CanCOLD - At risk - Quarterly follow-up 19 |
|
2017 (January) | 2017 (January) | |
| 22 | CanCOLD - At risk - Quarterly follow-up 20 |
|
2017 (April) | 2017 (April) | |
| 23 | CanCOLD - At risk - Quarterly follow-up 21 |
|
2017 (July) | 2017 (July) | |
| 24 | CanCOLD - At risk - Quarterly follow-up 22 |
|
2017 (October) | 2017 (October) | |
| 25 | CanCOLD - At risk - Quarterly follow-up 23 |
|
2018 (January) | 2018 (January) | |
| 26 | CanCOLD - At risk - Quarterly follow-up 24 |
|
2018 (April) | 2018 (April) | |
| 27 | CanCOLD - At risk - Quarterly follow-up 25 |
|
2018 (July) | 2018 (July) | |
| 28 | CanCOLD - At risk - Quarterly follow-up 26 |
|
2018 (October) | 2018 (October) | |
| 29 | CanCOLD - At risk - Quarterly follow-up 27 |
|
2019 (January) | 2019 (January) | |
| 30 | CanCOLD - At risk - Quarterly follow-up 28 |
|
2019 (April) | 2019 (April) | |
| 31 | CanCOLD - At risk - Quarterly follow-up 29 |
|
2019 (July) | 2019 (July) | |
| 32 | CanCOLD - At risk - Quarterly follow-up 30 |
|
2019 (October) | 2019 (October) | |
| 33 | CanCOLD - At risk - Quarterly follow-up 31 |
|
2020 (January) | 2020 (January) | |
| 34 | CanCOLD - At risk - Quarterly follow-up 32 |
|
2020 (April) | 2020 (April) | |
| 35 | CanCOLD - At risk - Quarterly follow-up 33 |
|
2020 (July) | 2020 (July) | |
| 36 | CanCOLD - At risk - Quarterly follow-up 34 |
|
2020 (October) | 2020 (October) | |
| 37 | CanCOLD - At risk - 54 months |
|
|
2021 | Ongoing |
| 38 | CanCOLD - At risk - Quarterly follow-up 35 |
|
2021 (January) | 2021 (January) | |
| 39 | CanCOLD - At risk - Quarterly follow-up 36 |
|
2021 (April) | 2021 (April) | |
| 40 | CanCOLD - At risk - Quarterly follow-up 37 |
|
2021 (July) | 2021 (July) | |
| 41 | CanCOLD - At risk - Quarterly follow-up 38 |
|
2021 (October) | 2021 (October) |
CanCOLD - Healthy controls
The population is composed of non-institutionalized adults, men and women, aged 40 and more, with a normal post bronchodilator spirometry, who are never smokers and without respiratory diseases.
Selection Criteria
- Minimum age
-
40
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- British Columbia
- Nova Scotia
- Ontario
- Quebec
- Saskatchewan
- Territory
- Montréal, Vancouver, Calgary, Halifax, Toronto, Ottawa, Kingston, Québec, Saskatoon
- Health Status
-
- With normal post bronchodilator spirometry and without respiratory diseases
- Other Criteria
- Never smoker, live near one of the study site
Sources of Recruitment
- General Population
-
- Random digit dialing
- Participants from Existing Studies
-
- The Canadian Obstructive Lung Disease (COLD) prevalence study
Sample Size
- Number of Participants
- 307
- Number of Participants with Biological Samples
- 273
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CanCOLD - Healthy controls - Baseline |
|
|
2009 (November) | 2015 (August) |
| 1 | CanCOLD - Healthy controls - 18 months |
|
|
2011 (June) | 2015 (November) |
| 2 | CanCOLD - Healthy controls - Quarterly follow-up 1 |
|
2012 (July) | 2012 (July) | |
| 3 | CanCOLD - Healthy controls - Quarterly follow-up 2 |
|
2012 (October) | 2012 (October) | |
| 4 | CanCOLD - Healthy controls - 36 months |
|
|
2013 (January) | 2019 (August) |
| 5 | CanCOLD - Healthy controls - Quarterly follow-up 3 |
|
2013 (January) | 2013 (January) | |
| 6 | CanCOLD - Healthy controls - Quarterly follow-up 4 |
|
2013 (April) | 2013 (April) | |
| 7 | CanCOLD - Healthy controls - Quarterly follow-up 5 |
|
2013 (July) | 2013 (July) | |
| 8 | CanCOLD - Healthy controls - Quarterly follow-up 6 |
|
2013 (October) | 2013 (October) | |
| 9 | CanCOLD - Healthy controls - Quarterly follow-up 7 |
|
2014 (January) | 2014 (January) | |
| 10 | CanCOLD - Healthy controls - Quarterly follow-up 8 |
|
2014 (April) | 2014 (April) | |
| 11 | CanCOLD - Healthy controls - Quarterly follow-up 9 |
|
2014 (July) | 2014 (July) | |
| 12 | CanCOLD - Healthy controls - Quarterly follow-up 10 |
|
2014 (October) | 2014 (October) | |
| 13 | CanCOLD - Healthy controls - Quarterly follow-up 11 |
|
2015 (January) | 2015 (January) | |
| 14 | CanCOLD - Healthy controls - Quarterly follow-up 12 |
|
2015 (April) | 2015 (April) | |
| 15 | CanCOLD - Healthy controls - Quarterly follow-up 13 |
|
2015 (July) | 2015 (July) | |
| 16 | CanCOLD - Healthy controls - Quarterly follow-up 14 |
|
2015 (October) | 2015 (October) | |
| 17 | CanCOLD - Healthy controls - Quarterly follow-up 15 |
|
2016 (January) | 2016 (January) | |
| 18 | CanCOLD - Healthy controls - Quarterly follow-up 16 |
|
2016 (April) | 2016 (April) | |
| 19 | CanCOLD - Healthy controls - Quarterly follow-up 17 |
|
2016 (July) | 2016 (July) | |
| 20 | CanCOLD - Healthy controls - Quarterly follow-up 18 |
|
2016 (October) | 2016 (October) | |
| 21 | CanCOLD - Healthy controls - Quarterly follow-up 19 |
|
2017 (January) | 2017 (January) | |
| 22 | CanCOLD - Healthy controls - Quarterly follow-up 20 |
|
2017 (April) | 2017 (April) | |
| 23 | CanCOLD - Healthy controls - Quarterly follow-up 21 |
|
2017 (July) | 2017 (July) | |
| 24 | CanCOLD - Healthy controls - Quarterly follow-up 22 |
|
2017 (October) | 2017 (October) | |
| 25 | CanCOLD - Healthy controls - Quarterly follow-up 23 |
|
2018 (January) | 2018 (January) | |
| 26 | CanCOLD - Healthy controls - Quarterly follow-up 24 |
|
2018 (April) | 2018 (April) | |
| 27 | CanCOLD - Healthy controls - Quarterly follow-up 25 |
|
2018 (July) | 2018 (July) | |
| 28 | CanCOLD - Healthy controls - Quarterly follow-up 26 |
|
2018 (October) | 2018 (October) | |
| 29 | CanCOLD - Healthy controls - Quarterly follow-up 27 |
|
2019 (January) | 2019 (January) | |
| 30 | CanCOLD - Healthy controls - Quarterly follow-up 28 |
|
2019 (April) | 2019 (April) | |
| 31 | CanCOLD - Healthy controls - Quarterly follow-up 29 |
|
2019 (July) | 2019 (July) | |
| 32 | CanCOLD - Healthy controls - Quarterly follow-up 30 |
|
2019 (October) | 2019 (October) | |
| 33 | CanCOLD - Healthy controls - Quarterly follow-up 31 |
|
2020 (January) | 2020 (January) | |
| 34 | CanCOLD - Healthy controls - Quarterly follow-up 32 |
|
2020 (April) | 2020 (April) | |
| 35 | CanCOLD - Healthy controls - Quarterly follow-up 33 |
|
2020 (July) | 2020 (July) | |
| 36 | CanCOLD - Healthy controls - Quarterly follow-up 34 |
|
2020 (October) | 2020 (October) | |
| 37 | CanCOLD - Healthy controls - 54 months |
|
|
2021 | Ongoing |
| 38 | CanCOLD - Healthy controls - Quarterly follow-up 35 |
|
2021 (January) | 2021 (January) | |
| 39 | CanCOLD - Healthy controls - Quarterly follow-up 36 |
|
2021 (April) | 2021 (April) | |
| 40 | CanCOLD - Healthy controls - Quarterly follow-up 37 |
|
2021 (July) | 2021 (July) | |
| 41 | CanCOLD - Healthy controls - Quarterly follow-up 38 |
|
2021 (October) | 2021 (October) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2021-10-28T16:56:50.666