Cambridge City over-75s Cohort Study

The CC75C is a long-term follow-up study of a representative population-based sample of older people. It aimed to study the prevalence, incidence and risk factors for cognitive decline and dementia.

Overview

Acronym
CC75C
Website
CC75C
Investigators
Prof. Carol Brayne
University of Cambridge
Dr. Tom R. Dening
University of Nottingham
Dr. Jane Fleming
University of Cambridge
Prof. Eugene S. Paykel
University of Cambridge
Dr. Stephen Barclay
University of Cambridge
Dr. Daniel Davis
University College London
Dr. Morag Farquhar
University of Cambridge
Dr. Elizabeta Mukaetova-Ladinska
Newcastle University
Contacts
Prof. Carol Brayne
University of Cambridge
Emily Zhao
University of Cambridge
Dr. Jane Fleming
University of Cambridge

General Design

Study design
Cohort
Start - End Year
1985 -
General Information on Follow Up (profile, frequency)

After the first survey, participants were followed-up at year 2, 7, 10, 13, 17, 21, 23, 25 and 28, for a total of 10 surveys to date.

Recruitment Target
  • Individuals
Number of Participants
2,166
Number of Participants with Biological Samples
284

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other

Marker Paper

Fleming J, Zhao E, O'Connor DW, Pollitt PA, Brayne C. Cohort profile: the Cambridge City over-75s Cohort (CC75C). International Journal of Epidemiology, 2007; 36(1): 40-6.

PUBMED 17510074

Timeline

Population

CC75C population

The baseline study targeted all men and women aged 75 years or older, who were registered with a selection of geographically and socially representative practices in Cambridge.

Selection Criteria

Minimum age
75
Countries
  • United Kingdom
Territory

Cambridge

Sources of Recruitment

Specific Population
  • Clinic patients
Supplementary Information

Participants were registered with a selection of general practices in Cambridge.

Sample Size

Number of Participants
2,166
Number of Participants with Biological Samples
284
Supplementary information about number of participants

Survey 1: 2166 participants

Survey 2: 1177 participants

Survey 3: 713 participants

Survey 4: 446 participants

Survey 5: 233 participants

Survey 6: 110 participants

Survey 7: 44 participants

Survey 8: 11 participants

Survey 9: 7 participants

Survey 10: 3 participants

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 CC75C - Survey 1
  • Questionnaires
  • Cognitive measures
1985 1988
1 CC75C - Survey 2
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Other : MRI
  • Other : Brain
1988 1990
2 CC75C - Survey 3
  • Questionnaires
  • Cognitive measures
  • Biosamples
  • Other : Brain
1992 1993
3 CC75C - Survey 4
  • Questionnaires
  • Cognitive measures
  • Biosamples
  • Blood
  • Other : Brain
1995 1995
4 CC75C - Survey 5
  • Questionnaires
  • Cognitive measures
  • Biosamples
  • Other : Brain
1998 1999
5 CC75C - Survey 6
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Other : Brain
2002 2003
6 CC75C - Survey 7
  • Questionnaires
  • Cognitive measures
  • Biosamples
  • Other : Voice recordings
  • Other : Brain
2006 2007
7 CC75C - Survey 8
  • Questionnaires
  • Cognitive measures
  • Biosamples
  • Other : Brain
2008 2009
8 CC75C - Survey 9
  • Questionnaires
  • Cognitive measures
  • Biosamples
  • Other : Brain
2010 2011
9 CC75C - Survey 10
  • Questionnaires
  • Cognitive measures
  • Biosamples
  • Other : Brain
2013 2013

Participating Studies

Acronym Name Study design Countries

Harmonization Initiatives Included

Acronym Name

Datasets

Name Data Collection Events Variables

Areas of Information Collected

Socio-demographic and economic characteristics
Death
Lifestyle and behaviours
Physical measures and assessments
Birth, pregnancy and reproductive health history
Laboratory measures
Perception of health, quality of life, development and functional limitations
Cognition, personality and psychological measures and assessments
Diseases
Life events, life plans, beliefs and values
Symptoms and signs
Preschool, school and work life
Medication and supplements
Social environment and relationships
Non-pharmacological interventions
Physical environment
Health and community care services utilization
Administrative information

Variables Content Summary

Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected

Networks

Acronym Name Harmonization Initiatives Individual Studies
Last Update: 2021-05-05T09:38:53.740