CHILD Cohort Study
Overview
- Acronym
- CHILD
- Website
- CHILD
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2008 -
- General Information on Follow Up (profile, frequency)
-
Measures such as questionnaires, tests and samples were taken from mothers, fathers and children during pregnancy at recruitment (second or third trimester) and 36 weeks, at birth, and 3 months, 6 months, 1 year, 1.5 years, 2 years, 2.5 years, 3 years, 4 years, 5 years and 8 years postpartum.
- Recruitment Target
-
- Families
- Number of Participants
- 9,875
- Number of Participants with Biological Samples
- 9,464
- Supplementary information about number of participants
-
Mothers: 3579 participants
Fathers: 2841 participants
Children: 3455 participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
- By contacting the study representative: CHILD National Coordinating Centre (McMaster University)
Sector of research
| Possible Access to Data | Possible Access to Biosamples | |
| Investigators from the public sector | ||
| Investigators from the private sector | ||
| Investigators from not-for-profit organization |
If an industry partner or private sector researcher are interested in working with the CHILD Cohort study, the study takes a collaborative research approach whereas the industry partner or private sector researcher is linked up with a CHILD Cohort Study Executive or Advisory Board member.
Transfer
| Possible Access to Data | Possible Access to Biosamples | |
| Can leave the study facility | ||
| Can leave the country |
All Investigators must apply to access CHILD data and samples, and sign a Materials and Information Transfer Agreement, which includes the conditions for access.
Cost
| Possible Access to Data | Not yet defined |
| Possible Access to Biosamples | Fixed Cost |
Cost reduction for co-analyses
| Possible Access to Data | |
| Possible Access to Biosamples |
larger sample numbers allow better pricing from analysis labs
Marker Papers
Subbarao P, et al. 2015. The Canadian Healthy Infant Longitudinal Development (CHILD) Study: examining developmental origins of allergy and asthma. Thorax. 70(10): 998-1000.
PUBMED 26069286Timeline
Populations
Selection Criteria
- Gender
-
Women only
- Minimum age
-
18
- Pregnant Women
-
- Second trimester
- Third trimester
- Countries
-
- Canada
- Territory
- British Columbia (Vancouver), Alberta (Edmonton), Manitoba (Winnipeg, Morden, Winkler), Ontario (Toronto)
- Other Criteria
- Second or third trimester of pregnancy
- Supplementary Information about Population
-
Approximately 25% non-Caucasian families
Sources of Recruitment
- General Population
-
- Volunteer enrolment
- Specific Population
-
- Clinic patients
- Supplementary Information
-
Parents were recruited at routine antenatal obstetrical ultrasound visits, person to person referrals, social media advertising, at kiosks at community events, malls and baby shows, and in health care locations.
Sample Size
- Number of Participants
- 3,579
- Number of Participants with Biological Samples
- 3,487
- Supplementary Information about Population
-
82 children failed inclusion criteria or met exclusion criteria at birth resulting in 3542 eligible mothers for follow-up.
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 | CHILD - Mothers - 18 weeks gestation | At 18 weeks the mothers answered questionnaires concerning their profile, health, ... |
2008 (January) | 2012 (December) |
| 1 | CHILD - Mothers - 36 weeks gestation | At 36 weeks the mothers answered a psychosocial questionnaire, collecting ... |
2008 (May) | 2013 (April) |
| 2 | CHILD - Mothers - Birth | At the time of birth, the mothers answered a questionnaire concerning their ... |
2008 (May) | 2013 (May) |
| 3 | CHILD - Mothers - 3 months postpartum | At 3 months postpartum, mothers answered questionnaires concerning their ... |
2008 (August) | 2013 (August) |
| 4 | CHILD - Mothers - 6 months postpartum | At 6 months postpartum, the mothers answered questionnaires concerning their ... |
2008 (November) | 2013 (November) |
| 5 | CHILD - Mothers - 1 year postpartum | At 1 year postpartum, the mothers answered questionnaires concerning their ... |
2009 (May) | 2014 (May) |
| 6 | CHILD - Mothers - 1.5 years postpartum | At 1.5 years postpartum, the mothers answered a questionnaire concerning their level ... | 2009 (November) | 2014 (November) |
| 7 | CHILD - Mothers - 2 years postpartum | At 2 years postpartum, the mothers answered questionnaires concerning their ... | 2010 (May) | 2015 (May) |
| 8 | CHILD - Mothers - 2.5 years postpartum | At 2.5 years postpartum, the mothers answered a questionnaire concerning their ... |
2010 (November) | 2015 (November) |
| 9 | CHILD - Mothers - 3 years postpartum | At 3 years postpartum, the mothers answered questionnaires concerning their ... |
2011 (May) | 2016 (May) |
| 10 | CHILD - Mothers - 4 years postpartum | At 4 years postpartum, the mothers answered questionnaires concerning their ... |
2012 (May) | 2017 (May) |
| 11 | CHILD - Mothers - 5 years postpartum | At 5 years postpartum, the mothers answered questionnaires concerning their ... |
2013 (May) | 2018 (May) |
| 12 | CHILD - Mothers - 8 years postpartum | At 8 years postpartum, the mothers answered questionnaires concerning their ... |
2018 (August) | 2020 (December) |
Selection Criteria
- Newborns
- Countries
-
- Canada
- Territory
- British Columbia (Vancouver), Alberta (Edmonton), Manitoba (Winnipeg, Morden, Winkler), Ontario (Toronto)
- Health Status
-
- Apparently healthy children
- Other Criteria
- Premature, in vitro and children that were expected to spend less than 80% of their time in the primary home or if there was any expectation to move away from a recruitment center within 1 year were excluded. Children with major congenital abnormalities or respiratory distress syndrome, or children of multiple births were excluded as well.
Sources of Recruitment
- Specific Population
-
- Other specific population : Children of mothers who were participating in the study when they were born.
Sample Size
- Number of Participants
- 3,455
- Number of Participants with Biological Samples
- 3,417
- Supplementary Information about Population
-
The number of participants with biological samples varies depending on the nature of sample and time point for collection (range 2000-3300).
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 | CHILD - Children - Birth | At birth, the parents answered questionnaires concerning the child delivery and his ... |
2008 (May) | 2012 (May) |
| 1 | CHILD - Children - 3 months postpartum | At 3 months postpartum, the parents answered questionnaires concerning the child's ... |
2008 (August) | 2013 (August) |
| 2 | CHILD - Children - 6 months postpartum | At 6 months postpartum, the parents answered questionnaires concerning the child's ... | 2008 (November) | 2013 (November) |
| 3 | CHILD - Children - 1 year postpartum | At 1 year postpartum, the parents answered questionnaires concerning the child's ... |
2009 (May) | 2014 (May) |
| 4 | CHILD - Children - 1.5 years postpartum | At 1.5 years postpartum, the parents answered questionnaires concerning the child's ... |
2009 (November) | 2014 (November) |
| 5 | CHILD - Children - 2 years postpartum | At 2 years postpartum, the parents answered questionnaires concerning the child's ... | 2010 (May) | 2015 (May) |
| 6 | CHILD - Children - 2.5 years postpartum | At 2.5 years postpartum, the parents answered questionnaires concerning the child's ... |
2010 (November) | 2015 (November) |
| 7 | CHILD - Children - 3 years postpartum | At 3 years postpartum, the parents answered questionnaires concerning the child's ... |
2011 (May) | 2016 (May) |
| 8 | CHILD - Children - 4 years postpartum | At 4 years postpartum, the parents answered questionnaires concerning the child's ... | 2012 (May) | 2017 (May) |
| 9 | CHILD - Children - 5 years postpartum | At 5 years postpartum, the parents answered questionnaires concerning the child's ... |
2013 (May) | 2018 (May) |
| 10 | CHILD - Children - 8 years postpartum | At 8 years postpartum, the parents answered questionnaires concerning the child's ... |
2018 (August) | 2020 (December) |
Selection Criteria
- Gender
-
Men only
- Countries
-
- Canada
- Territory
- British Columbia (Vancouver), Alberta (Edmonton), Manitoba (Winnipeg, Morden, Winkler), Ontario (Toronto)
Sources of Recruitment
- Specific Population
-
- Other specific population : Partners of the women and fathers of the children who were recruited to participate in the CHILD study.
- Supplementary Information
-
Some fathers participated, however, their participation was not a mandatory requirement. Fathers were eligible to join the study at any time during follow-up.
Parents were recruited at routine antenatal obstetrical ultrasound visits, person to person referrals, social media advertising, at kiosks at community events, malls and baby shows, and in health care locations.
Sample Size
- Number of Participants
- 2,841
- Number of Participants with Biological Samples
- 2,560
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 | CHILD - Fathers - 18 weeks gestation | At 18 weeks gestation, fathers answered questionnaires concerning their health and ... |
2008 (January) | 2012 (December) |
| 1 | CHILD - Fathers - 1 year postpartum | At 1 year postpartum, fathers answered a questionnaire concerning their ... |
2009 (May) | 2014 (May) |
| 2 | CHILD - Fathers - 5 years postpartum | At 5 years postpartum, fathers answered questionnaires concerning their health and ... |
2013 (May) | 2018 (May) |
| 3 | CHILD - Fathers - 8 years postpartum | At 8 years postpartum, fathers answered questionnaires concerning their health and ... |
2018 (August) | 2020 (December) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Datasets
| Name | Type | Data Collection Events | Variables |
|---|