Cellular Immunity and Seroprevalence of Antibodies against SARS-CoV-2: Characterisation of Three Populations of Food Workers
The main objective of this project is to determine the immune response against SARS-CoV-2 in 3 worker populations using a group of hardware workers as a comparator.
Specifically, this study will serve to:
* Determine the seroprevalence of antibodies to SARS-CoV-2 by different techniques;
* Measure the incidence of SARS-CoV-2 infection at 12 and 24 weeks;
* Compare the different serological techniques used in this study;
* Measure the innate response at time 0 and 24 weeks;
* Measure the acquired cellular response at time 0 and 24 weeks;
* Define the demographic characteristics of these populations;
* Describe the protective measures used at work;
* Determine the risk factors associated with severe COVID case in this population;
* Establish correlations between risk factors and SARS-CoV-2 infection;
* Establish correlations between the different arms of the immune system;
* Validate two new serological tests; and
* Explore the immune response to the vaccine in vaccinated participants.
Overview
- Acronym
- CISACOV
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2021 - 2022
- General Information on Follow Up (profile, frequency)
-
After enrollment (time 0), participants are followed-up at 12 and 24 weeks. A supplementary visit took place for participants who tested positive for SARS-CoV-2 by PCR.
- Recruitment Target
-
- Individuals
- Number of Participants
- 600
- Number of Participants with Biological Samples
- 600
- Supplementary information about number of participants
-
Grocery store workers: 150 participants
Food workers: 300 participants
Hardware store workers: 150 participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Timeline
Populations
CISACOV - Grocery store workers
The population is composed of 18 years old and older individuals who work at a grocery store in the regions of Capitale Nationale or Chaudière-Appalaches in Quebec, Canada, who have been present at work at least for 20 days since February 1st, 2020 and were in contact with the public in the course of work.
Selection Criteria
- Minimum age
-
18
- Countries
-
- Canada
- Canadian Provinces
-
- Quebec
- Territory
- Capitale Nationale, Chaudière-Appalaches, Quebec
- Health Status
-
- Absence of active COVID; no anemia.
- Other Criteria
-
Inclusion: Occupation as a retailer, in contact with the public in the course of work and present at work for at least 20 days starting from February 1st, 2020, and able to come to CHUL for the study.
Exclusion: Was in contact with a COVID-19 case in the last 14 days, was hospitalized for COVID-19, has donated blood in the last 4 weeks, or is pregnant.
Sources of Recruitment
- Specific Population
-
- Other specific population : Workers in a grocery store.
- Supplementary Information
-
Participants were recruited by sending workers a letter or an email explaining the study via the distribution lists of the Confederation of National Trade Unions (CSN) and the Quebec Hardware and Building Supply Association (AQMAT) and inviting them to contact the study team if interested.
Sample Size
- Number of Participants
- 150
- Number of Participants with Biological Samples
- 150
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CISACOV - Grocery store workers - Enrollment |
|
|
2021 (April) | 2021 (September) |
| 1 | CISACOV - Grocery store workers - Week 12 |
|
|
2021 (June) | 2021 (December) |
| 2 | CISACOV - Grocery store workers - Week 24 |
|
|
2021 (September) | 2022 (March) |
| 3 | CISACOV - Grocery store workers - COVID positive |
|
|
2021 (March) | 2022 (March) |
CISACOV - Food workers
The population is composed of 18 years old and older individuals who work at a restaurant or bar in the regions of Capitale Nationale or Chaudière-Appalaches in Quebec, Canada, who have been present at work at least for 20 days since February 1st, 2020 and were in contact with the public in the course of work.
Selection Criteria
- Minimum age
-
18
- Countries
-
- Canada
- Canadian Provinces
-
- Quebec
- Territory
- Capitale Nationale, Chaudière-Appalaches, Quebec
- Health Status
-
- Absence of active COVID; no anemia.
- Other Criteria
-
Inclusion: Occupation as a retailer, in contact with the public in the course of work and present at work for at least 20 days starting from February 1st, 2020, and able to come to CHUL for the study.
Exclusion: Was in contact with a COVID-19 case in the last 14 days, was hospitalized for COVID-19, has donated blood in the last 4 weeks, or is pregnant.
Sources of Recruitment
- Specific Population
-
- Other specific population : Workers in a restaurant or bar.
- Supplementary Information
-
Participants were recruited by sending workers a letter or an email explaining the study via the distribution lists of the Confederation of National Trade Unions (CSN) and the Quebec Hardware and Building Supply Association (AQMAT) and inviting them to contact the study team if interested.
Sample Size
- Number of Participants
- 300
- Number of Participants with Biological Samples
- 300
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CISACOV - Food workers - Enrollment |
|
|
2021 (April) | 2021 (September) |
| 1 | CISACOV - Food workers - Week 12 |
|
|
2021 (June) | 2021 (December) |
| 2 | CISACOV - Food workers - Week 24 |
|
|
2021 (September) | 2022 (March) |
| 3 | CISACOV - Food workers - COVID positive |
|
|
2021 (March) | 2022 (March) |
CISACOV - Hardware store workers
The population is composed of 18 years old and older individuals who work at a hardware store in the regions of Capitale Nationale or Chaudière-Appalaches in Quebec, Canada, who have been present at work at least for 20 days since February 1st, 2020 and were in contact with the public in the course of work.
Selection Criteria
- Minimum age
-
18
- Countries
-
- Canada
- Canadian Provinces
-
- Quebec
- Territory
- Capitale Nationale, Chaudière-Appalaches, Quebec
- Health Status
-
- Absence of active COVID; no anemia.
- Other Criteria
-
Inclusion: Occupation as a retailer, in contact with the public in the course of work and present at work for at least 20 days starting from February 1st, 2020, and able to come to CHUL for the study.
Exclusion: Was in contact with a COVID-19 case in the last 14 days, was hospitalized for COVID-19, has donated blood in the last 4 weeks, or is pregnant.
Sources of Recruitment
- Specific Population
-
- Other specific population : Workers in a hardware store.
- Supplementary Information
-
Participants were recruited by sending workers a letter or an email explaining the study via the distribution lists of the Confederation of National Trade Unions (CSN) and the Quebec Hardware and Building Supply Association (AQMAT) and inviting them to contact the study team if interested.
Sample Size
- Number of Participants
- 150
- Number of Participants with Biological Samples
- 150
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CISACOV - Hardware store workers - Enrollment |
|
|
2021 (April) | 2021 (September) |
| 1 | CISACOV - Hardware store workers - Week 12 |
|
|
2021 (June) | 2021 (December) |
| 2 | CISACOV - Hardware store workers - Week 24 |
|
|
2021 (September) | 2022 (March) |
| 3 | CISACOV - Hardware store workers - COVID positive |
|
|
2021 (March) | 2022 (March) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2022-05-26T11:28:10.327