Canadian Longitudinal Study on Aging

The Canadian Longitudinal Study on Aging (CLSA) is a large, national, long-term study that will follow approximately 50,000 men and women between the ages of 45 and 85 for at least 20 years. The study aims to collect information on the changing biological, medical, psychological, social, lifestyle and economic aspects of people’s lives. These factors will be studied in order to understand aging as a dynamic process and the interrelationship among intrinsic and extrinsic factors from mid-life to older age.

Overview

Acronym
CLSA
Website
CLSA
Investigators
Dr. Parminder Raina
McMaster University
Dr. Susan Kirkland
Dalhousie University
Dr. Christina Wolfson
McGill University
Contacts
Data Access Inquiries
Dr. Ine Wauben
McMaster University

General Design

Study design
Cohort
Start - End Year
2011 -
General Information on Follow Up (profile, frequency)
Each participant is re-contacted every three years and is followed for at least 20 years or until death. In 2020, a subset of participants were also followed weekly, biweekly, and monthly for the COVID-19 questionnaire, the COVID-19 antibody blood collection, and the COVID-19 brain health collection.
Recruitment Target
  • Individuals
Number of Participants
51,338
Number of Participants with Biological Samples
30,000
Supplementary Information
CLSA cohort participants who become institutionalized during the course of the study will continue to be followed either through personal or proxy interview.

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other
  • By contacting the study representative: Data Access Inquiries
General inquiries: info@clsa-elcv.ca

Marker Papers

Raina P, Wolfson C, Kirkland S, et al. Corrigendum to: Cohort Profile: The Canadian Longitudinal Study on Aging (CLSA). Int J Epidemiol. 2019 Dec 1;48(6):2066. doi: 10.1093/ije/dyz221. Erratum for: Int J Epidemiol. 2019 Dec 1;48(6):1752-1753j.

PUBMED 31605135

Supplementary Information

Raina P, Wolfson C., Kirkland S, Griffith L.E., et al. (2019) Cohort profile: The Canadian Longitudinal Study on Aging (CLSA). International Journal of Epidemiology, Volume 48, Issue 6, 1752-1753j https://doi.org/10.1093/ije/dyz173

Timeline

Populations

CLSA - Tracking

This population is composed of a representative sample of Canadians aged 45 to 85 years who consented to a telephone interview.

Selection Criteria

Minimum age
45
Maximum age
85
Countries
  • Canada
Canadian Provinces
  • Alberta
  • British Columbia
  • Manitoba
  • New Brunswick
  • Newfoundland and Labrador
  • Nova Scotia
  • Ontario
  • Prince Edward Island
  • Quebec
  • Saskatchewan
Other Criteria
The population may include: * Individuals living in households and transitional housing arrangements (e.g., seniors’ residences, in which only minimal care is provided) * Individuals living in long-term care institutions (i.e., those providing 24-hour nursing care). * First Nations, Metis, and Inuit descents living on and not living on Indigenous settlements. * Full-time members of Canadian Forces.

Sources of Recruitment

General Population
  • Random digit dialing
Specific Population
  • Other specific population : Provincial health registries
Participants from Existing Studies
  • Canadian Community Health Survey (CCHS) - Healthy Aging
Supplementary Information

The Canadian Community Health Survey (CCHS) cycle 4.2 was used as the recruitment vehicle for the telephone interview cohort.

Sample Size

Number of Participants
21,241

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 CLSA - Tracking - Baseline
  • Questionnaires
  • Cognitive measures
2011 (September) 2015 (December)
1 CLSA - Tracking - Follow-up 1
  • Questionnaires
  • Cognitive measures
2015 (December) 2018 (December)
2 CLSA - Tracking - Decedent questionnaire
  • Questionnaires
2017 Ongoing
3 CLSA - Tracking - Follow-up 2
  • Questionnaires
  • Cognitive measures
2018 2021
4 CLSA - Tracking - COVID-19 baseline questionnaire
  • Questionnaires
2020 2020
5 CLSA - Tracking - COVID-19 antibody
  • Questionnaires
  • Biosamples
  • Blood
2020 2021
6 CLSA - Tracking - COVID-19 brain health
  • Questionnaires
  • Cognitive measures
2021 2021
7 CLSA - Tracking - Follow-up 3
  • Questionnaires
  • Cognitive measures
2021 2024
CLSA - Comprehensive

This population is composed of a random sample of Canadians aged 45 to 85 years who consented to an in-home interview and a physical examination component.

Selection Criteria

Minimum age
45
Maximum age
85
Countries
  • Canada
Canadian Provinces
  • Alberta
  • British Columbia
  • Manitoba
  • Newfoundland and Labrador
  • Nova Scotia
  • Ontario
  • Quebec
Territory

Vancouver, Victoria, Surrey, Calgary, Winnipeg, Hamilton, Ottawa, Montréal, Sherbrooke, Halifax, and St. John’s

Other Criteria
The population may include: * Individuals living in households and transitional housing arrangements (e.g., seniors’ residences, in which only minimal care is provided) * Individuals living in long-term care institutions (i.e., those providing 24-hour nursing care). * First Nations, Metis, and Inuit descents living on and not living on Indigenous settlements. * Full-time members of Canadian Forces.

Sources of Recruitment

General Population
  • Selected sample
  • Random digit dialing
Specific Population
  • Other specific population : Provincial registries
Supplementary Information

Provincial health registration databases were used for recruitment of the comprehensive cohort. Individuals residing within a 25-50 kilometer radius of the 11 Data collection sites (Vancouver, Victoria, Surrey, Calgary, Winnipeg, Hamilton, Ottawa, Montreal, Sherbrooke, Halifax, and St. John’s) were also recruited.

Sample Size

Number of Participants
30,097
Number of Participants with Biological Samples
30,000

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 CLSA - Comprehensive - Baseline
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
  • Urine
2012 2015
1 CLSA - Comprehensive - Follow-up 1
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
  • Urine
2015 2018
2 CLSA - Comprehensive - Decedent questionnaire
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
  • Urine
2017 Ongoing
3 CLSA - Comprehensive - Follow-up 2
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
  • Urine
2018 2021
4 CLSA - Comprehensive - COVID-19 questionnaire
  • Questionnaires
2020 2020
5 CLSA - Comprehensive - COVID-19 Antibody
  • Biosamples
  • Blood
2020 2021
6 CLSA - Comprehensive - COVID-19 brain health
  • Cognitive measures
  • Physical measures
2021 2021
7 CLSA - Comprehensive - Follow-up 3
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
2021 2024

Participating Studies

Acronym Name Study design Countries

Harmonization Initiatives Included

Acronym Name

Datasets

Name Data Collection Events Variables

Areas of Information Collected

Socio-demographic and economic characteristics
Death
Lifestyle and behaviours
Physical measures and assessments
Birth, pregnancy and reproductive health history
Laboratory measures
Perception of health, quality of life, development and functional limitations
Cognition, personality and psychological measures and assessments
Diseases
Life events, life plans, beliefs and values
Symptoms and signs
Preschool, school and work life
Medication and supplements
Social environment and relationships
Non-pharmacological interventions
Physical environment
Health and community care services utilization
Administrative information

Variables Content Summary

Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected

Networks

Acronym Name Harmonization Initiatives Individual Studies
Last Update: 2024-04-11T10:46:29.971