CoLaus|PsyCoLaus
The main objective of CoLaus|PsyCoLaus is to study mental disorders and cardiovascular risk factors or diseases as well as their associations in the community.
More specifically, the study aims to assess the following:
* The associations of physical cardiovascular risk factors (obesity, diabetes, dyslipidemia, hypertension), mental disorders (mood, substance use and, anxiety disorders), and health behaviors (smoking, inactivity, diet) with the development of atherosclerotic cardiovascular diseases (myocardial diseases and stroke) and mortality.
* The associations of physical cardio-vascular risk factors, and health-related behaviors with the development of mental disorders and cognitive decline.
* The role of genes, health-related behaviors, inflammation and stress in the associations of mental disorders with physical cardio-vascular risk factors, atherosclerotic cardiovascular diseases, and cognitive decline.
* The effects of sex and gender on health behaviors, cardiovascular risk factors, and mental disorders.
* The role of genes, familial and environmental factors in the parent-offspring transmission of mental disorders and cardiovascular risk factors.
Overview
- Acronym
- CoLaus|PsyCoLaus
- Website
- CoLaus|PsyCoLaus
- Investigators
-
Prof. Julien VaucherLausanne University Hospital – CHUV and University of Lausanne/University Teaching and Research Hospital and University of Fribourg
- Contacts
-
Prof. Julien VaucherLausanne University Hospital – CHUV and University of Lausanne/University Teaching and Research Hospital and University of Fribourg
General Design
- Study design
- Cohort
- Start - End Year
- 2003 -
- General Information on Follow Up (profile, frequency)
-
**Probands** Recruitment went from 2003 to 2006. The physical baseline evaluation went from May 2003 to June 2006, and the psychiatric baseline evaluation went from January 2004 to May 2009. Participants were followed up for the physical evaluations between April 2009 and September 2012, May 2014 and April 2017, April 2018 and March 2021, and have been followed since January 2022 for the fourth follow-up. Participants were followed up for the psychiatric evaluations between January 2004 and May 2009, April 2010 and January 2014, November 2014 and July 2018, and April 2018 and September 2021, and have been followed up for the fourth wave since October 2021. Participants could participate in physical, psychiatric, or both evaluations. **Metabolic Probands** Recruitment for physical and psychiatric baseline evaluations went from 2010 to 2014. Participants were followed up for physical evaluations between May 2014 and April 2017, April 2018 and March 2021, and have been followed since January 2022. Participants were followed up for psychiatric evaluations between November 2014 and July 2018, April 2018 and September 2021, and have been followed since October 2021. **Relatives (of the probands)**
Offspring younger than 18 years and spouses of the probands of this cohort were recruited between 2007 and 2012 for the psychiatric baseline evaluation and were thereafter followed up every 3 years. Adult first-degree relatives were recruited between 2007 and 2012 for psychiatric and physical evaluations and were thereafter followed up every 3 years. Offspring aged 18 to 35 were recruited from 2019 to 2023 for physical and psychiatric evaluations and have been followed up every 3 years since 2019. **Relatives (of the metabolic probands)** Offspring and spouses of the probands were recruited between 2010 and 2014 for the baseline psychiatric evaluation and have since been followed up every 3 years. Starting in 2014, spouses and adult offspring have also undergone physical evaluations every 3 years.
- Recruitment Target
-
- Individuals
- Number of Participants
- 10,312
- Number of Participants with Biological Samples
- 7,769
- Supplementary information about number of participants
-
Probands (population-based cohort): 6734 participants
Metabolic Probands : 90 participants
Relatives of the probands of the population-based cohort, recruited from 2007 to 2012 (psychiatric investigations only):
Parents: 219 participants
Siblings: 416 participants
Offspring (aged 18-years and older): 573 participants
Spouses: 388 participants
Minor offspring (younger than 18 years): 521 participants
Relatives of the probands of the population-based cohort recruited from 2019 to 2023 (physical and psychiatric investigations):
Offspring aged 18 to 35 years: 1350 participants
Relatives of the probands of the metabolic cohort:
Offspring: 14 participants
Spouses: 7 participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Papers
Firmann M, Mayor V, Vidal PM, et al. The CoLaus study: a population-based study to investigate the epidemiology and genetic determinants of cardiovascular risk factors and metabolic syndrome. BMC Cardiovascular Disorder, 2008; Mar 17;8:6.
PUBMED 18366642Preisig M, Waeber G, Vollenweider P, et al. The PsyCoLaus study: methodology and characteristics of the sample of a population-based survey on psychiatric disorders and their association with genetic and cardiovascular risk factors. BMC Psychiatry. 2009 Mar 17;9:9.
PUBMED 19292899Supplementary Information
**Probands**
Population-based cohort: Participants were randomly selected among the residents of the city of Lausanne according to the civil register between 2003 and 2006. The objectives were to study cardio-vascular risk factors and mental disorders as well as their associations in the general population. The baseline investigation also included genetic and environmental factors that could predispose to the development of cardiovascular diseases, such as ischemic myocardial diseases or stroke and psychiatric and cognitive disorders.
Physical and psychiatric information on these probands is available from 6733 and 5144 participants, respectively.
Data on participants aged 65 years and older of this study have been used to build The Swiss Ageing Citizen Reference (SACR)
**Metabolic Probands** Metabolic cohort: Given the relative rareness of severe mental disorders in the general population, a cohort of psychiatric patients with schizophrenia, bipolar disorder or major depressive disorder originally enrolled in a study on metabolic complications under psychotropic drug treatment was recruited during the first follow-up of the population-based cohort. These patients were in the age range of the original cohort, fulfilled the same inclusion and exclusion criteria, had the same physical and psychiatric assessment as the original cohort and were followed-up in parallel. **Relatives of the Probands** The objectives of the recruitment of offspring younger than 18 years and spouses from 2007 to 2012 were to prospectively study the associations of parental disorders and environmental factors with the risk of onset of mental disorders during adolescence and young adulthood. The objectives of the recruitment of adult first-degree relatives and spouses from 2007 and 2012 were to determine the patterns of familial aggregation of mental disorders, to assess spouse similarity and assortative mating and to explore the mechanisms underlying the associations between mental disorders and cardiovascular risk factors through the investigation of patterns of aggregation and cross-aggregation of these disorders. The objectives of the recruitment of adult offspring from 2019 to 2023 were to assess mental disorders and obesity markers in young adulthood as well as their associations, to identify factors involved in these associations and to determine the genetic, familial and environmental determinants of the parent-offspring transmission of mental disorders and obesity markers. **Relatives of the Metabolic Probands (only psychiatric evaluations)** The objectives of the recruitment of offspring younger than 18 years and spouses from 2010 to 2014 were to prospectively study the associations of severe parental disorders and environmental factors with the risk of onset of mental disorders during adolescence and young adulthood.Timeline
Populations
CoLaus|PsyCoLaus - Probands
The population is composed of predominantly European descent Lausanne inhabitants aged 35 to 75 years.
Selection Criteria
- Minimum age
-
35
- Maximum age
-
75
- Countries
-
- Switzerland
- Territory
- City of Lausanne
Sources of Recruitment
- General Population
-
- Selected sample
- Supplementary Information
-
A random sampling procedure based on a complete list of the inhabitants of Lausanne aged 35 to 75 years, according to the civil register of the city, was used. Subjects who agreed to participate were contacted by phone within 14 days. Subjects who did not answer the first invitation were sent a second invitation letter. If no answer was obtained, participants were contacted by phone. After completion of the physical evaluation, participants were contacted by the psychiatric team by letters and phone calls to elicit consent for the psychiatric part.
Sample Size
- Number of Participants
- 6,734
- Number of Participants with Biological Samples
- 6,733
- Supplementary information about number of participants
-
Total cohort at Baseline: 6734 participants
Physical evaluation Baseline: 6733 participants
Psychiatric evaluation Baseline: 3720 participants
Physical evaluation Follow-up 1: 5064 participants
Psychiatric evaluation Follow-up 1: 4007 participants
Physical evaluation Follow-up 2: 4881 participants
Psychiatric evaluation Follow-up 2: 3667 participants
Physical evaluation Follow-up 3: 3972 participants
Psychiatric evaluation Follow-up 3: 3018 participants
The cohort is composed of 52.6% of women and 91% European descent. The cohort did not significantly differ from the population of Lausanne with respect to the sex distribution, but the two youngest and the two oldest age bands were underrepresented.
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CoLaus|PsyCoLaus - Probands - Physical evaluation baseline |
|
|
2003 (May) | 2006 (June) |
| 1 | CoLaus|PsyCoLaus - Probands - Psychiatric evaluation baseline |
|
2004 (January) | 2009 (May) | |
| 2 | CoLaus|PsyCoLaus - Probands - Physical evaluation follow-up 1 |
|
|
2009 (April) | 2012 (September) |
| 3 | CoLaus|PsyCoLaus - Probands - Psychiatric evaluation follow-up 1 |
|
|
2010 (April) | 2014 (January) |
| 4 | CoLaus|PsyCoLaus - Probands - Physical evaluation follow-up 2 |
|
|
2014 (May) | 2017 (April) |
| 5 | CoLaus|PsyCoLaus - Probands - Psychiatric evaluation follow-up 2 |
|
2014 (November) | 2018 (July) | |
| 6 | CoLaus|PsyCoLaus - Probands - Physical evaluation follow-up 3 |
|
|
2018 (April) | 2021 (March) |
| 7 | CoLaus|PsyCoLaus - Probands - Psychiatric evaluation follow-up 3 |
|
2018 (April) | 2021 (September) | |
| 8 | CoLaus|PsyCoLaus - Probands - Psychiatric evaluation follow-up 4 |
|
2021 (October) | Ongoing | |
| 9 | CoLaus|PsyCoLaus - Probands - Physical evaluation follow-up 4 |
|
|
2022 (October) | Ongoing |
CoLaus|PsyCoLaus - First-degree Relatives
The population is composed of adult first-degree relatives (biological parents and siblings) of the probands.
Selection Criteria
- Minimum age
-
18
Sources of Recruitment
- General Population
-
- Selected sample
- Supplementary Information
-
During the psychiatric evaluations between 2007 and 2012, all participants (probands) from the original cohort (probands) were systematically asked, whether they would allow the study to contact their first-degree relatives. If they agreed, written consent was requested for each relative in order to give the study permission to contact this person and to complete a brief self-report pedigree including the addresses and phone numbers of their relatives. These relatives were then invited by letter to participate. Those who agreed were contacted by a psychologist by phone, who provided further information on the study and sent them the detailed information letter and consent forms.
Sample Size
- Number of Participants
- 635
- Supplementary information about number of participants
-
Parents: 219 participants
Siblings: 416 participants
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CoLaus|PsyCoLaus - First-degree Relatives - Psychiatric evaluation |
|
2007 | 2012 | |
| 1 | CoLaus|PsyCoLaus - First-degree Relatives - Physical evaluation baseline |
|
|
2007 | 2012 |
| 2 | CoLaus|PsyCoLaus - First-degree Relatives - Psychiatric evaluation follow-up 1 |
|
|
2010 | 2015 |
| 3 | CoLaus|PsyCoLaus - First-degree Relatives - Physical evaluation follow-up 1 |
|
|
2010 | 2015 |
| 4 | CoLaus|PsyCoLaus - First-degree Relatives - Psychiatric evaluation follow-up 2 |
|
2013 | 2017 | |
| 5 | CoLaus|PsyCoLaus - First-degree Relatives - Physical evaluation follow-up 2 |
|
|
2013 | 2017 |
| 6 | CoLaus|PsyCoLaus - First-degree Relatives - Psychiatric evaluation follow-up 3 |
|
2016 | 2020 | |
| 7 | CoLaus|PsyCoLaus - First-degree Relatives - Physical evaluation follow-up 3 |
|
|
2016 | 2020 |
CoLaus|PsyCoLaus - Spouses
The population is composed of probands’ spouses aged 18 years and older.
Selection Criteria
- Minimum age
-
18
Sources of Recruitment
- General Population
-
- Selected sample
- Supplementary Information
-
During the psychiatric evaluations between 2007 and 2012 all participants (probands) of the original cohort were systematically asked whether they would allow the study to contact their first-degree relatives. If they agreed, written consent was also requested to contact their spouse. The spouse was then invited by letter to participate. Those who agreed were contacted by a psychologist by phone, who provided further information on the study and sent them the detailed information letter and consent forms.
Sample Size
- Number of Participants
- 388
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CoLaus|PsyCoLaus - Spouses - Psychiatric evaluation baseline |
|
2007 | 2012 | |
| 1 | CoLaus|PsyCoLaus - Spouses - Physical evaluation baseline |
|
|
2007 | 2012 |
| 2 | CoLaus|PsyCoLaus - Spouses - Psychiatric evaluation follow-up 1 |
|
|
2010 | 2015 |
| 3 | CoLaus|PsyCoLaus - Spouses - Physical evaluation follow-up 1 |
|
|
2010 | 2015 |
| 4 | CoLaus|PsyCoLaus - Spouses - Psychiatric evaluation follow-up 2 |
|
2013 | 2017 | |
| 5 | CoLaus|PsyCoLaus - Spouses - Physical evaluation follow-up 2 |
|
|
2013 | 2017 |
| 6 | CoLaus|PsyCoLaus - Spouses - Psychiatric evaluation follow-up 3 |
|
2016 | 2020 | |
| 7 | CoLaus|PsyCoLaus - Spouses - Physical evaluation follow-up 3 |
|
|
2016 | 2020 |
CoLaus|PsyCoLaus - Minor Offspring
The population is composed of probands’ children aged 4 to 17 years.
Selection Criteria
- Minimum age
-
4
- Maximum age
-
17
Sources of Recruitment
- General Population
-
- Selected sample
- Supplementary Information
-
During the psychiatric evaluations between 2007 and 2012 all participants (probands) of the original cohort were systematically asked whether they would allow the study to contact their minor offspring aged 4 to 17 years. If they agreed, written consent was requested for each minor child to give the study permission to contact this child. These children were then invited by letter to participate. Those who agreed were contacted by a psychologist by phone, who provided further information on the study and sent them the detailed information letter and consent forms. Consent was requested from both parents and children.
Sample Size
- Number of Participants
- 521
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CoLaus|PsyCoLaus - Minor Offspring - Psychiatric evaluation baseline |
|
2007 | 2012 | |
| 1 | CoLaus|PsyCoLaus - Minor Offspring - Psychiatric evaluation follow-up 1 |
|
2010 | 2015 | |
| 2 | CoLaus|PsyCoLaus - Minor Offspring - Psychiatric evaluation follow-up 2 |
|
2013 | 2018 | |
| 3 | CoLaus|PsyCoLaus - Minor Offspring - Psychiatric evaluation follow-up 3 |
|
2016 | 2021 |
CoLaus|PsyCoLaus - Adult Offspring
The population is composed of the offspring aged 18 to 35 years of the probands.
Selection Criteria
- Minimum age
-
18
- Maximum age
-
35
- Countries
-
- Switzerland
Sources of Recruitment
- General Population
-
- Selected sample
- Supplementary Information
-
During the third and the fourth physical and psychiatric follow-up evaluation, all participants (probands) of the original cohort were systematically asked whether they would allow the study to contact their offspring in the age range between 18 and 35 years. If they agreed, written consent was requested for each offspring to give the study permission to contact this person. These offspring were then invited by letter to participate. Those who agreed were contacted by a psychologist or study nurse by phone, who provided further information on the study and sent them the detailed information letter and consent forms. Those who completed first the psychiatric evaluation, were contacted by the somatic team in a second step and vice versa.
Sample Size
- Number of Participants
- 1,923
- Number of Participants with Biological Samples
- 998
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CoLaus|PsyCoLaus - Adult Offsping - Psychiatric evaluation baseline |
|
2019 | 2023 | |
| 1 | CoLaus|PsyCoLaus - Adult Offsping - Physical evaluation baseline |
|
|
2019 | 2023 |
| 2 | CoLaus|PsyCoLaus - Adult Offsping - Psychiatric evaluation follow-up 1 |
|
2022 | 2026 | |
| 3 | CoLaus|PsyCoLaus - Adult Offsping - Physical evaluation follow-up 1 |
|
|
2022 | 2026 |
| 4 | CoLaus|PsyCoLaus - Adult Offsping - Psychiatric evaluation follow-up 2 |
|
2025 | 2029 | |
| 5 | CoLaus|PsyCoLaus - Adult Offsping - Physical evaluation follow-up 2 |
|
|
2025 | 2029 |
| 6 | CoLaus|PsyCoLaus - Adult Offsping - Psychiatric evaluation follow-up 3 |
|
2028 | 2032 | |
| 7 | CoLaus|PsyCoLaus - Adult Offsping - Physical evaluation follow-up 3 |
|
|
2028 | 2032 |
CoLaus|PsyCoLaus - Metabolic Probands
The population is composed of psychiatric patients with schizophrenia, bipolar disorder or major depressive disorder who are predominantly from European descent and are Lausanne inhabitants aged 35 to 75 years.
Selection Criteria
- Minimum age
-
35
- Maximum age
-
75
- Countries
-
- Switzerland
- Territory
- City of Lausanne
- Health Status
-
- Psychiatric patients with schizophrenia, bipolar disorder or major depressive disorder.
Sources of Recruitment
- Participants from Existing Studies
-
- From a study on metabolic complications under psychotropic drug treatment
- Supplementary Information
-
In parallel to the first follow-up of the original cohort (probands), psychiatric patients with schizophrenia, bipolar disorder or major depressive disorder, enrolled in a study on metabolic complications under psychotropic drug treatment and in the age range of the original cohort (probands), were systematically contacted by letter and phone to ask whether they would be willing to participate. After completion of the psychiatric evaluation, participants were contacted by the somatic team by letters and phone calls to elicit consent also for the physical part.
Sample Size
- Number of Participants
- 90
- Number of Participants with Biological Samples
- 38
- Supplementary information about number of participants
-
Parents of the original cohort participants: 1 participant
Siblings of the original cohort participants: 1 participant
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CoLaus|PsyCoLaus - Metabolic Probands - Psychiatric evaluation baseline |
|
|
2010 (January) | 2014 (January) |
| 1 | CoLaus|PsyCoLaus - Metabolic Probands - Physical evaluation baseline |
|
|
2010 (January) | 2014 (January) |
| 2 | CoLaus|PsyCoLaus - Metabolic Probands - Physical evaluation follow-up 1 |
|
|
2014 (May) | 2017 (April) |
| 3 | CoLaus|PsyCoLaus - Metabolic Probands - Psychiatric evaluation follow-up 1 |
|
2014 (November) | 2018 (July) | |
| 4 | CoLaus|PsyCoLaus - Metabolic Probands - Physical evaluation follow-up 2 |
|
|
2018 (April) | 2021 (March) |
| 5 | CoLaus|PsyCoLaus - Metabolic Probands - Psychiatric evaluation follow-up 2 |
|
2018 (April) | 2021 (September) | |
| 6 | CoLaus|PsyCoLaus - Metabolic Probands - Psychiatric evaluation follow-up 3 |
|
2021 (October) | Ongoing | |
| 7 | CoLaus|PsyCoLaus - Metabolic Probands - Physical evaluation follow-up 3 |
|
|
2022 (October) | Ongoing |
CoLaus|PsyCoLaus - Metabolic Spouses
The population is composed of spouses of the probands who are psychiatric patients with schizophrenia, bipolar disorder, or major depressive disorder, are predominantly of European descent, and are Lausanne inhabitants aged 35 to 75 years.
Selection Criteria
- Minimum age
-
35
- Maximum age
-
75
- Countries
-
- Switzerland
- Territory
- City of Lausanne
- Health Status
-
- Psychiatric patients with schizophrenia, bipolar disorder or major depressive disorder.
Sources of Recruitment
- Participants from Existing Studies
-
- From a study on metabolic complications under psychotropic drug treatment
- Supplementary Information
-
During the psychiatric baseline evaluation of the participants (probands) of the metabolic cohort 2010-2014, participants were systematically asked whether they would allow the study to contact their spouses. The spouse was then invited by letter to participate. Those who agreed were contacted by a psychologist by phone, who provided further information on the study and sent them the detailed information letter and consent forms. In parallel to the first follow-up of the original cohort (probands), psychiatric patients with schizophrenia, bipolar disorder or major depressive disorder, enrolled in a study on metabolic complications under psychotropic drug treatment and in the age range of the original cohort (probands), were systematically contacted by letter and phone to ask whether they would be willing to participate. After completion of the psychiatric evaluation, participants were contacted by the somatic team by letters and phone calls to elicit consent also for the physical part.
Sample Size
- Number of Participants
- 7
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CoLaus|PsyCoLaus - Metabolic Spouses - Psychiatric evaluation baseline |
|
|
2010 | 2014 |
| 1 | CoLaus|PsyCoLaus - Metabolic Spouses - Psychiatric evaluation follow-up 1 |
|
2013 | 2017 | |
| 2 | CoLaus|PsyCoLaus - Metabolic Spouses - Physical evaluation baseline |
|
|
2014 | 2017 |
| 3 | CoLaus|PsyCoLaus - Metabolic Spouses - Psychiatric evaluation follow-up 2 |
|
2016 | 2020 | |
| 4 | CoLaus|PsyCoLaus - Metabolic Spouses - Physical evaluation follow-up 1 |
|
|
2017 | 2020 |
| 5 | CoLaus|PsyCoLaus - Metabolic Spouses - Psychiatric evaluation follow-up 3 |
|
2019 | 2023 | |
| 6 | CoLaus|PsyCoLaus - Metabolic Spouses - Physical evaluation follow-up 2 |
|
|
2020 | 2023 |
| 7 | CoLaus|PsyCoLaus - Metabolic Spouses - Physical evaluation follow up 3 |
|
|
2023 | Ongoing |
CoLaus|PsyCoLaus - Metabolic Offspring
The population is composed of the offspring of the probands who are psychiatric patients with schizophrenia, bipolar disorder or major depressive disorder, are predominantly from European descent, and are Lausanne inhabitants aged 35 to 75 years.
Selection Criteria
- Minimum age
-
35
- Maximum age
-
75
- Territory
- City of Lausanne
- Health Status
-
- Psychiatric patients with schizophrenia, bipolar disorder or major depressive disorder.
Sources of Recruitment
- Participants from Existing Studies
-
- From a study on metabolic complications under psychotropic drug treatment
- Supplementary Information
-
During the psychiatric baseline evaluation of the participants (probands) of the metabolic cohort 2010-2014, they were systematically asked whether they would allow the study to contact their offspring. Those who agreed were contacted by a psychologist by phone, who provided further information on the study and sent them the detailed information letter and consent forms. In parallel to the first follow-up of the original cohort (probands), psychiatric patients with schizophrenia, bipolar disorder or major depressive disorder, enrolled in a study on metabolic complications under psychotropic drug treatment and in the age range of the original cohort (probands), were systematically contacted by letter and phone to ask whether they would be willing to participate. After completion of the psychiatric evaluation, participants were contacted by the somatic team by letters and phone calls to elicit consent also for the physical part.
Sample Size
- Number of Participants
- 7
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CoLaus|PsyCoLaus - Metabolic Offspring - Psychiatric evaluation baseline |
|
|
2010 | 2014 |
| 1 | CoLaus|PsyCoLaus - Metabolic Offspring - Psychiatric evaluation follow-up 1 |
|
2013 | 2017 | |
| 2 | CoLaus|PsyCoLaus - Metabolic Offspring - Physical evaluation baseline |
|
|
2014 | 2017 |
| 3 | CoLaus|PsyCoLaus - Metabolic Offspring - Psychiatric evaluation follow-up 2 |
|
2016 | 2020 | |
| 4 | CoLaus|PsyCoLaus - Metabolic Offspring - Physical evaluation follow-up 1 |
|
|
2017 | 2020 |
| 5 | CoLaus|PsyCoLaus - Metabolic Offspring - Psychiatric evaluation follow-up 3 |
|
2019 | 2023 | |
| 6 | CoLaus|PsyCoLaus - Metabolic Offspring - Physical evaluation follow-up 2 |
|
|
2020 | 2023 |
| 7 | CoLaus|PsyCoLaus - Metabolic Offspring - Physical evaluation follow-up 3 |
|
|
2023 | Ongoing |
CoLaus|PsyCoLaus - Metabolic Minor Offspring
The population is composed of probands’ children aged 4 to 17 years of age who are psychiatric patients with schizophrenia, bipolar disorder, or major depressive disorder, predominantly of European descent, and residents of Lausanne.
Selection Criteria
- Minimum age
-
4
- Maximum age
-
17
- Countries
-
- Switzerland
- Territory
- City of Lausanne
- Health Status
-
- Psychiatric patients with schizophrenia, bipolar disorder or major depressive disorder.
Sources of Recruitment
- Participants from Existing Studies
-
- From a study on metabolic complications under psychotropic drug treatment
- Supplementary Information
-
During the psychiatric baseline evaluation of the participants (probands) of the metabolic cohort 2010-2014, they were systematically asked, whether they would allow the study to contact their minor offspring aged 4 to 17 years. If they agreed, written consent was requested for each minor child to give the study permission to contact this child. These children were then invited by letter to participate. Those who agreed were contacted by a psychologist by phone, who provided further information on the study and sent them the detailed information letter and consent forms. Consent was requested from both parents and children.
Sample Size
- Number of Participants
- 7
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | CoLaus|PsyCoLaus - Metabolic Minor Offspring - Psychiatric evaluation baseline |
|
|
2010 | 2014 |
| 1 | CoLaus|PsyCoLaus - Metabolic Minor Offspring - Psychiatric evaluation follow-up 1 |
|
2013 | 2017 | |
| 2 | CoLaus|PsyCoLaus - Metabolic Minor Offspring - Psychiatric evaluation follow-up 2 |
|
2016 | 2020 | |
| 3 | CoLaus|PsyCoLaus - Metabolic Minor Offspring - Psychiatric evaluation follow-up 3 |
|
2019 | 2023 |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2025-09-22T09:34:16.663