The Comprehensive Assessment of Neurodegeneration and Dementia Study
The major goals of the COMPASS-ND study are:
- To learn about who is at risk of developing dementia;
- To determine how early dementia can be detected;
- To find out what tests are most effective at detecting dementia; and
- To assess commonalities and differences of different types of dementia in terms of mechanisms and presentation.
Overview
- Acronym
- COMPASS-ND
- Website
- COMPASS-ND
- Investigators
-
- Contacts
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General Design
- Study design
- Cohort
- Start - End Year
- 2016 -
- General Information on Follow Up (profile, frequency)
-
In-person assessments are completed at baseline and at subsequent 24-months intervals. Annual telephone checks are also conducted.
- Recruitment Target
-
- Individuals
- Number of Participants
- 1,650
- Number of Participants with Biological Samples
- 1,650
- Supplementary information about number of participants
-
- 300 participants with subjective cognitive impairment (SCI);
- 400 participants with mild cognitive impairment (MCI);
- 200 participants with vascular cognitive impairment with subcortical ischemic lesions (VCI);
- 150 participants with mild Alzheimer's disease (AD);
- 200 participants with mild mixed dementia (Alzheimer's disease plus vascular elements);
- 200 participants with Lewey Body Dementia (LBD) or Parkinson's disease dementia (PDD);
- 200 participants with frontotemporal disease (FTD).
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Paper
Das S., Mohades Z., Strauss T., Campbell T., Borrie M., Fogarty J., Whitehead V., Pillon R.,Lindsay J., Best S.Comprehensive Assessment of Neurodegeneration and Dementia (COMPASS-ND) Study: Implementing the Clinical Cohorts Platform. Canadian Geriatrics Journal. 2016 Sep; 19(3): 154–155.
PUBMED 31309917Timeline
Population
COMPASS-ND population
The population is composed of men and women, aged between 50 and 90, living with, or at risk for developing, dementia, and who were enrolled in 30 sites across Canada.
Selection Criteria
- Minimum age
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50
- Maximum age
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90
- Countries
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- Canada
- Canadian Provinces
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- Alberta
- British Columbia
- Newfoundland and Labrador
- Ontario
- Prince Edward Island
- Quebec
- Saskatchewan
- Territory
- St. John, Quebec City, Montreal, Ottawa, Toronto, Kitchener/Waterloo, London, Saskatoon, Edmonton, Calgary, Vancouver and Prince George.
- Health Status
-
- Participants with the following memory conditions were recruited : subjective cognitive impairment (SCI); mild cognitive impairment (MCI); subcortical ischemic vascular MCI; mild Alzheimer's disease; dementia of mixed etiology; Lewy Body disease; Parkinson's dementia and frontotemporal dementia.
Sources of Recruitment
- Specific Population
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- Clinic patients
- Supplementary Information
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Participants were recruited from different sites: memory clinics, stroke clinics, movement disorder clinics, and behavioural neurology clinics as well as both academic and private research groups.
Sample Size
- Number of Participants
- 1,650
- Number of Participants with Biological Samples
- 1,650
- Supplementary information about number of participants
-
Baseline: 1600 participants
2 years follow-up: 1390 participants
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | COMPASS-ND - Baseline |
|
|
2016 (April) | 2018 (March) |
| 1 | COMPASS-ND - 2 years follow-up |
|
|
2018 (April) | 2020 (March) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2023-08-10T18:18:41.393