Determinants of Community COVID-19 Transmission: Learning from the Hutterites
The overall goal of this study is to understand the community determinants of COVID-19 transmission.
Specific objectives are:
* To determine if pre-existing SARS- CoV-2 antibodies in children prevents subsequent infection in others (i.e. is there a herd effect),
* To define longitudinal SARS-CoV-2 viral load in children and its relationship to colony transmission,
* To determine the role of physical distancing in COVID-19 colony transmission,
* To assess the diagnostic accuracy of respiratory and serological specimens that are being used to detect COVID-19,
* To determine the effect of influenza on SARS-CoV-2 infection at the individual and community level,
* To assess re-introduction of SARS-CoV-2 viruses in colonies by whole genome sequencing.
Overview
- Acronym
- DCCT
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2021 -
- General Information on Follow Up (profile, frequency)
-
In the main phase, colonies or participants are followed-up biweekly over 2 to 6 month (surveillance), at mid-point and at the end of the trial. In the extension phase, enrolled colonies and new colonies/participants are followed-up weekly for up to 3 months (active surveillance) and at the end of the trial. In the Omicron variant extension phase, enrolled colonies or participants are followed-up weekly for up to 6 months (active surveillance), at mid-point and at the end of the study.
- Recruitment Target
-
- Other : Hutterite colonies living in Alberta and in Saskatchewan
- Number of Participants
- 2,065
- Supplementary information about number of participants
-
This study was conducted in 20 Hutterite colonies in which the mean population size of the study colonies is 103 (range 62 to 143) members, with on average 24 households per colony.
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Timeline
Populations
DCCT - Main Cohort
The population is composed of all Hutterite colony members, of any age, who are living in Alberta and in Saskatchewan.
Selection Criteria
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- Saskatchewan
- Ethnic Origin
-
- Hutterite
- Supplementary Information about selection criteria
-
Participants are either from one of the 15 colonies in Alberta or from one of the 5 colonies in Saskatchewan.
Sources of Recruitment
- Specific Population
-
- Other specific population : Hutterite colonies
- Supplementary Information
-
Surveillance research assistants kept in communication with Hutterite colony members, after a close collaboration of at least 3 years with them and 10 colonies participated.
Sample Size
- Number of Participants
- 697
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | DCCT - Main Cohort - Baseline |
|
|
2021 (January) | 2021 (January) |
| 1 | DCCT - Main Cohort - Surveillance |
|
|
2021 (January) | 2021 (June) |
| 2 | DCCT - Main Cohort - Mid-point serology |
|
|
2021 (March) | 2021 (March) |
| 3 | DCCT - Main Cohort - Final serology |
|
|
2021 (June) | 2021 (June) |
DCCT - Extension Cohort
The population is composed of both enrolled colonies of Hutterite in the main cohort and new colonies who are living in Alberta and in Saskatchewan.
Selection Criteria
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- Saskatchewan
- Ethnic Origin
-
- Hutterite
- Supplementary Information about selection criteria
-
Participants are either from one of the 15 colonies in Alberta or from one of the 5 colonies in Saskatchewan.
Sources of Recruitment
- Specific Population
-
- Other specific population : Hutterite colonies
- Supplementary Information
-
Participants are recruited from 16 colonies: some continuing colonies from the main cohort and some new colonies.
Sample Size
- Number of Participants
- 1,332
- Supplementary information about number of participants
-
Continuing colonies: 697 participants
New colonies: 635 participants
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | DCCT - Extension Cohort - Baseline |
|
|
2021 (July) | 2021 (July) |
| 1 | DCCT - Extension Cohort - Surveillance |
|
|
2021 (July) | 2021 (October) |
| 2 | DCCT - Extension Cohort - Final serology |
|
|
2021 (October) | 2021 (October) |
DCCT - Omicron Variant Cohort
The population is composed of all Hutterite colony members, of any age, who are living in Alberta and in Saskatchewan under the emergence of the omicron variant of SARS-CoV-2 virus.
Selection Criteria
- Countries
-
- Canada
- Canadian Provinces
-
- Alberta
- Saskatchewan
- Ethnic Origin
-
- Hutterite
- Supplementary Information about selection criteria
-
Participants are either from one of the 15 colonies in Alberta or from one of the 5 colonies in Saskatchewan.
Sources of Recruitment
- Specific Population
-
- Other specific population : Hutterite colonies
- Supplementary Information
-
Participants are recruited from 14 continuing colonies.
Sample Size
- Number of Participants
- 1,198
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | DCCT - Omicron Variant Cohort - Baseline |
|
|
2022 (January) | 2022 (January) |
| 1 | DCCT - Omicron Variant Cohort - Surveillance |
|
|
2022 (January) | 2022 (September) |
| 2 | DCCT - Omicron Variant Cohort - Mid-point serology |
|
|
2022 (May) | 2022 (May) |
| 3 | DCCT - Omicron Variant Cohort - Final serology |
|
|
2022 (October) | 2022 (October) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2024-02-27T13:29:44.883