Children and COVID-19: seroprevalence study
The objectives of this study are to:
* Estimate the seroprevalence of SARS-CoV-2 in children in Montréal, representative of age groups;
* Compare the seroprevalence of SARS-CoV-2 in children in different neighbourhoods of Montréal;
* Estimate the risk of seroconversion of SARS-CoV-2 in children in Montréal from the beginning to the end of the school year;
* Estimate the seroprevalence of SARS-CoV-2 in daycare and school personnel in Montreal
* Estimate the risk of seroconversion of SARS-CoV-2 in daycare and school personnel in Montréal.
The secondary objectives are to:
* Estimate the prevalence of emotional and mental health difficulties of children in different neighbourhoods of Montréal.
* Estimate the change in prevalence of emotional and mental health difficulties of children in Montréal from the beginning to the end of the school year.
* Estimate the prevalence of emotional and mental health difficulties of daycare and school personnel in Montréal.
Overview
- Acronym
- EnCORE
- Website
- EnCORE
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2020 - 2023
- General Information on Follow Up (profile, frequency)
-
EnCORE is an open cohort and welcomed new children during the longitudinal follow-up. * Round 2 is the first follow up for the children enrolled in Round 1. * Round 3 is the second follow-up for the children that enrolled at Round 1 and the first follow-up for the children that enrolled at Round 2. * Round 4 is the first follow-up for the children enrolled in Round 3, the second follow-up for the children enrolled in Round 2 and the third follow-up for children enrolled in Round 1. * Round 5 is the first follow-up for the children enrolled in Round 4, the second follow-up for the children enrolled in Round 3, the third follow-up for children enrolled in Round 2, and the fourth follow-up for children enrolled in Round 1.
- Recruitment Target
-
- Individuals
- Number of Participants
- 6,671
- Number of Participants with Biological Samples
- 5,300
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Papers
Zinszer K, McKinnon B, Bourque N, et al. Seroprevalence of SARS-CoV-2 Antibodies Among Children in School and Day Care in Montreal, Canada. JAMA Netw Open. 2021 Nov 1;4(11):e2135975. doi: 10.1001/jamanetworkopen.2021.35975.
PUBMED 34812845Zinszer K, McKinnon B, Bourque N, et al. Seroprevalence of anti-SARS-CoV-2 antibodies among school and daycare children and personnel: protocol for a cohort study in Montreal, Canada. BMJ Open. 2021 Jul 8;11(7):e053245. doi: 10.1136/bmjopen-2021-053245.
PUBMED 34244288Zinszer K, Charland K, Pierce L, et al. Pre-Omicron seroprevalence, seroconversion, and seroreversion of infection-induced SARS-CoV-2 antibodies among a cohort of children and teenagers in Montréal, Canada. Int J Infect Dis. 2023 Jun;131:119-126. doi: 10.1016/j.ijid.2023.03.036.
PUBMED 36963656Timeline
Populations
EnCORE - Children
The population is composed of children 2 to 17 years old in the selected daycare and schools (West Island, Hochelaga-Maisonneuve, Montréal-Nord, and Plateau).
Selection Criteria
- Minimum age
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2
- Maximum age
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17
- Countries
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- Canada
- Canadian Provinces
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- Quebec
- Territory
- Montreal (West Island, Hochelaga-Maisonneuve Montréal-Nord, and Plateau)
- Health Status
-
- Exclusion: * Individuals with chronic disease or other health conditions that preclude participation in the study.
Sources of Recruitment
- General Population
-
- Selected sample
- Supplementary Information
-
Participants were recruited from the different school boards and daycare associations that operate within the selected neighbourhoods though letters of invitations and social media.
Sample Size
- Number of Participants
- 4,916
- Number of Participants with Biological Samples
- 4,916
- Supplementary Information about selection criteria
-
All participants who previously participated in the first round were invited to participate in the following rounds. For example, a participant of round 1 can also participate in round 2, 3, 4 and 5.
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | EnCORE - Children - Round 1 |
|
|
2020 (October) | 2021 (April) |
| 2 | EnCORE - Children - Round 2 |
|
|
2021 (May) | 2021 (September) |
| 3 | EnCORE - Children - Round 3 |
|
|
2021 (November) | 2022 (February) |
| 3 | EnCORE - Children - Round 4 |
|
|
2022 (May) | 2022 (October) |
| 4 | EnCORE - Children - Round 5 |
|
|
2023 (February) | 2023 (May) |
EnCORE - Daycare and School Personnel
The population is composed of all daycare and school personnel in the selected daycares and schools (in West Island, Hochelaga-Maisonneuve, Montréal-Nord, and Plateau).
Selection Criteria
- Countries
-
- Canada
- Canadian Provinces
-
- Quebec
- Territory
- Montreal (West Island, Hochelaga-Maisonneuve Montréal-Nord, and Plateau)
- Health Status
-
- Exclusion: chronic disease or other health conditions that preclude participation in the study
Sources of Recruitment
- Specific Population
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- Other specific population : Personnel from the children's daycare and school
- Supplementary Information
-
Participants were recruited from the different school boards and daycare associations that operate within the selected neighbourhoods though letters of invitations and social media.
Sample Size
- Number of Participants
- 382
- Number of Participants with Biological Samples
- 363
- Supplementary Information about selection criteria
-
95% of participants provided a blood sample for serology analysis.
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | EnCORE - Daycare and School Personnel - Data collection |
|
|
2021 (March) | 2021 (August) |
EnCORE - Household
The population is composed of household members of the children from the selected daycare and schools (West Island, Hochelaga-Maisonneuve, Montréal-Nord, and Plateau).
Selection Criteria
- Countries
-
- Canada
- Canadian Provinces
-
- Quebec
- Territory
- Montreal (West Island, Hochelaga-Maisonneuve Montréal-Nord, and Plateau)
Sources of Recruitment
- General Population
-
- Selected sample
- Supplementary Information
-
Participants are recruited from the children household from the study.
Sample Size
- Number of Participants
- 1,373
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | EnCORE - Household - Questionnaire |
|
2021 (June) | 2021 (October) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
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Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2024-06-07T16:08:46.567