European Prospective Investigation into Cancer and Nutrition - Turin
EPIC is a multi-centre prospective cohort based on healthy, middle-aged subjects who agree, following an active invitation, to participate in the study and to have their health status followed-up for the rest of their lives. The study is based in ten European countries and includes populations characterized by large variations in dietary habits and cancer risk.
The EPIC study aims to investigate the relationships between diet, nutritional status, lifestyle and environmental factors, and the incidence of cancer and other chronic diseases.
The Turin component of the European Prospective Investigation into Cancer and Nutrition (EPIC) is a prospective cohort of 10,604 men and women living in the city of Turin, Northern Italy, some of whom are blood donors and healthy volunteers.
One of the main objectives of the Turin component of The European Prospective Investigation into Cancer and Nutrition (EPIC) is to examine the role of diet-related exposure in the etiology of cancer and its interaction with other environmental and/or genetic determinants. The main field of research in the EPIC-Turin Study is molecular epidemiology, particularly on the formation of haemoglobin and DNA adducts in relation to tobacco smoking and on the role of metabolic polymorphisms.
Overview
- Acronym
- EPIC - Turin
- Website
- EPIC - Turin
- Investigators
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Dr Carlotta SacerdoteCentro di Riferimento per l'Epidemiologia e la Prevenzione Oncologica in Piemonte
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 1993 -
- General Information on Follow Up (profile, frequency)
-
Baseline started in 1993. From 1998 on, participants were followed-up annually though collaboration with the local cancer registry, the demographic computerized archives of the Torino region and the discharge report database for hospital patients. In 2009 participants were followed-up through a questionnaire.
- Recruitment Target
-
- Individuals
- Number of Participants
- 10,604
- Number of Participants with Biological Samples
- 10,604
- Supplementary information about number of participants
-
6047 men and 4557 women were recruited.
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Paper
Palli D, Berrino F, Vineis P, Tumino R, Panico S, Masala G, et al. A molecular epidemiology project on diet and cancer: the EPIC-Italy Prospective Study. Design and baseline characteristics of participants. Tumori 2003;89(6) 586-593.
PUBMED 14870823Timeline
Population
Selection Criteria
- Minimum age
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35
- Countries
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- Italy
- Territory
- City of Torino
Sources of Recruitment
- General Population
-
- Selected sample
- Specific Population
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- Members of an association
- Supplementary Information
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Recruitment took place in 1993-1998 and involved blood donors, employees, volunteers and medical test users at National Health Service (NHS).Participant eligibility within each cohort was based essentially on geographic or administrative boundaries.
Sample Size
- Number of Participants
- 10,604
- Number of Participants with Biological Samples
- 10,604
- Supplementary information about number of participants
-
Baseline: 10 604 participants
Follow-up questionnaire: 6362 participants
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | EPIC-Turin - Baseline |
|
|
1993 | 1999 |
| 1 | EPIC-Turin - Cancer and mortality registries 1 |
|
1998 | 1999 | |
| 2 | EPIC-Turin - Cancer and mortality registries 2 |
|
2000 | 2001 | |
| 3 | EPIC-Turin - Cancer and mortality registries 3 |
|
2002 | 2003 | |
| 4 | EPIC-Turin - Cancer and mortality registries 4 |
|
2004 | 2005 | |
| 5 | EPIC-Turin - Cancer and mortality registries 5 |
|
2006 | 2007 | |
| 6 | EPIC-Turin - Cancer and mortality registries 6 |
|
2008 | 2009 | |
| 7 | EPIC-Turin - Follow-up questionnaire |
|
2009 | 2009 | |
| 8 | EPIC-Turin - Cancer and mortality registries 7 |
|
2010 | 2011 | |
| 9 | EPIC-Turin - Cancer and mortality registries 8 |
|
2012 | 2013 | |
| 10 | EPIC-Turin - Cancer and mortality registries 9 |
|
2014 | 2015 | |
| 11 | EPIC-Turin - Cancer and mortality registries 10 |
|
2016 | 2017 |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
Areas of Information Collected per per Population and Data Collection Event
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|