Epidemiology for Health
The primary objective of the EpiHealth cohort study is to provide an open-access resource to study interactions between genotypes and life-style factors in a large cohort (300 000 individuals) derived from the Swedish population in the ages 45 to 75 years regarding the future development of common degenerative disorders, such as myocardial infarction, stroke, heart failure, fractures/osteoporosis, dementia, obstructive lung disease, osteoarthritis/pain, obesity/type 2 diabetes, and cancer. Moreover, secondary objectives of EpiHealth are:
- To study prevalence’s of common degenerative disorders in the Swedish population in the ages 45-75 years;
- To study life-style patterns in the ages 45-75 years and differences between genders;
- To study heritability of common degenerative disorders in the Swedish population by using data from families attending both EpiHealth and LifeGene studies;
- To evaluate novel biomarkers in serum and plasma for future common degenerative disorders;
- To study the relationships between genotypes and future development of common degenerative disorders;
- To study the relationships between life-style factors and future development of common degenerative disorders.
Overview
- Acronym
- EpiHealth
- Website
- EpiHealth
- Contacts
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General Design
- Study design
- Cohort
- Start - End Year
- 2011 -
- General Information on Follow Up (profile, frequency)
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Following the baseline investigation, repeated collection of data on exposures from the web-based questionnaires and test center visits are planned for every 5th and 10th year respectively.
- Recruitment Target
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- Individuals
- Number of Participants
- 25,000
- Number of Participants with Biological Samples
- 25,000
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
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Marker Paper
Lind L, Elmståhl S, Bergman E, Englund M, Lindberg E, Michaelsson K, Nilsson PM, Sundström J. EpiHealth: a large population-based cohort study for investigation of gene-lifestyle interactions in the pathogenesis of common diseases. Eur J Epidemiol. 2013 Feb; 28(2): 189-97.
PUBMED 23435790Timeline
Population
EpiHealth - Population
The study population is composed of persons aged between 45 and 75 years, who have a permanent address in Sweden and a civic registration number.
Selection Criteria
- Minimum age
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45
- Maximum age
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75
- Countries
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- Sweden
Sources of Recruitment
- General Population
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- Selected sample
- Supplementary Information
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A randomization procedure will assure that all age-groups and both genders are equally represented in the main study. The majority of the sample will be included based on population-based randomization using official registries and/or commercial address databases.
Sample Size
- Number of Participants
- 25,000
- Number of Participants with Biological Samples
- 25,000
Data Collection Events
| # | Name | Description | Start | End |
|---|---|---|---|---|
| 0 | EpiHealth - Baseline | During the baseline investigation, data collection came from three primary sources: ... |
2011 (April) | 2016 (December) |
Participating Studies
| Acronym | Name | Study design | Countries |
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Harmonization Initiatives Included
| Acronym | Name |
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Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
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Datasets
| Name | Type | Data Collection Events | Variables |
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Last Update: 2021-10-19 19:01