Enquête de Santé Psychologique-Risques, Incidence et Traitement

Objective of ESPRIT is to study the etiopathogenesis of psychiatric disorders in elderly people, to determine life risk factors in older persons with a psychiatric history. - To determine current and lifetime prevalence and incidence of psychiatric disorders in the elderly; - To identify sub-groups of depressive symptoms; - To describe modifications of stress responses related to age; - To examine risk factors for psychiatric disorders and their interactions; - To evaluate usefulness of a complete genome investigation based on haplotypes and of a pilot study on clinical pools based on symptoms severity; - To find etiological models derived from multiple risk factors and interactions to explain disease onset and symptoms severity; - To suggest, based on these models, future prevention and intervention strategies.

Overview

Acronym
ESPRIT
Investigators
Pr. Karen Ritchie
Hôpital La Colombière
Dr. Marie-Laure Ancelin
Hôpital La Colombière
Contacts
Dr. Isabelle Carrière
Hôpital La Colombière

General Design

Study design
Cohort
Start - End Year
1999 -
General Information on Follow Up (profile, frequency)
Participants were followed up after 2, 4, 7, 10, 12, and 15 years.
Recruitment Target
  • Individuals
Number of Participants
2,270
Number of Participants with Biological Samples
2,270

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other

Marker Paper

Ritchie, K., Carrière, I., Ritchie, C.W., Berr, C., Artero, S., Ancelin, M-L. Designing prevention programmes to reduce incidence of dementia: prospective cohort study of modifiable risk factors. BMJ 2010; 341:c3885

PUBMED 20688841

Timeline

Population

ESPRIT Population
Men and women aged 65 years and over, registered on electoral list of Montpellier and its district (cohort of participants having known war - 1st and 2nd World War, Algerian War, Spanish War).

Selection Criteria

Minimum age
65
Countries
  • France
Territory
Montpellier

Sources of Recruitment

General Population
  • Selected sample

Sample Size

Number of Participants
2,270
Number of Participants with Biological Samples
2,270
Supplementary information about number of participants
Baseline: 2270 participants
Follow-up 1: 2034 participants
Follow-up 2: 2003 participants
Follow-up 3: 1303 participants
Follow-up 4: 1195 participants
Follow-up 5: 1087 participants
Follow-up 6: 648 participants

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 ESPRIT Population - DCE1
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
  • Saliva
1999 (March) 2001
1 ESPRIT Population - DCE2
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
  • Saliva
2001 2003
2 ESPRIT Population - DCE3
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
  • Saliva
2003 2005
3 ESPRIT Population - DCE4
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
  • Saliva
2006 2008
4 ESPRIT Population - DCE5
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
  • Saliva
2009 2011
5 ESPRIT Population - DCE6
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
  • Saliva
2011 2013
6 ESPRIT Population - DCE7
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Blood
  • Saliva
2014 2016

Participating Studies

Acronym Name Study design Countries

Harmonization Initiatives Included

Acronym Name

Datasets

Name Data Collection Events Variables

Areas of Information Collected

Socio-demographic and economic characteristics
Death
Lifestyle and behaviours
Physical measures and assessments
Birth, pregnancy and reproductive health history
Laboratory measures
Perception of health, quality of life, development and functional limitations
Cognition, personality and psychological measures and assessments
Diseases
Life events, life plans, beliefs and values
Symptoms and signs
Preschool, school and work life
Medication and supplements
Social environment and relationships
Non-pharmacological interventions
Physical environment
Health and community care services utilization
Administrative information

Variables Content Summary

Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected

Networks

Acronym Name Harmonization Initiatives Individual Studies
Last Update: 2023-08-10T18:18:24.674