Lothian Birth Cohort 1936
The original aim of the LBC1936 study was to seek determinants of normal cognitive ageing in survivors of the Scottish Mental Survey 1947. Those determinants of lifetime cognitive ageing were to include genetic, information processing, medical, economic and psycho-social factors. Wave 2 of LBC1936 was intended to identify the mechanisms that cause white matter damage and how this causes cognitive decline with ageing. New to Wave 2 was that the LBC1936 subjects underwent detailed structural MRI brain scan.
Overview
- Acronym
- LBC1936
- Website
- LBC1936
- Investigators
-
- Contacts
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General Design
- Study design
- Cohort
- Start - End Year
- 2004 -
- General Information on Follow Up (profile, frequency)
-
The LBC1936 participants undertook a general intelligence test at age 11 years and were recruited for the LBC1936 cohort at the mean age of 70. They have been examined at mean ages of 70, 73 and 76 years.
- Recruitment Target
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- Other : Sub-sample of the participants of the Scottish Mental Survey of 1947
- Number of Participants
- 1,091
- Number of Participants with Biological Samples
- 1,091
- Supplementary information about number of participants
-
548 men and 543 women.
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Paper
Deary IJ, Gow AJ, Pattie A, Starr JM. Cohort profile: the Lothian Birth Cohorts of 1921 and 1936. Int J Epidemiol. 2012 Dec;41(6):1576-84.
PUBMED 22253310Timeline
Population
A sub-sample of the Scottish Mental Survey 1947. The mean age of the participants was 70 years old at wave 1, 73 years old at wave 2 and 76 years old at wave 3.
Selection Criteria
- Countries
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- United Kingdom
- Territory
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Edinburgh and the surrounding area.
- Other Criteria
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Only the available participants who had completed all previous waves were invited.
Sources of Recruitment
- Participants from Existing Studies
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- The Scottish Mental Survey 1947
- Supplementary Information
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Between 2004 and 2007, individuals from Edinburgh and the Lothians who might have taken part in the 1947 Survey were invited to participate in the LBC1936.
Sample Size
- Number of Participants
- 1,091
- Number of Participants with Biological Samples
- 1,091
- Supplementary information about number of participants
-
Wave 1: 1091 participants (548 men and 543 women)
Wave 2: 866 participants (448 men and 418 women)
Wave 3: 697 participants (360 men and 337 women)
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | LBC1936 - Wave 1 |
|
|
2004 (January) | 2007 (May) |
| 1 | LBC1936 - Wave 2 |
|
|
2007 (October) | 2010 (May) |
| 2 | LBC1936 - Wave 3 |
|
|
2011 (July) | 2013 (November) |
Participating Studies
| Acronym | Name | Study design | Countries |
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Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
Areas of Information Collected per per Population and Data Collection Event
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|