Leipzig Longitudinal Study of the Aged
LEILA75+ is a prospective population-based cohort study on the epidemiology of dementia and mild cognitive impairment (MCI). The aims of the study are to determine the prevalence and incidence of dementia and of MCI, as well as the occurrence of related conditions such as subjective cognitive decline, and to identify their risk factors.
Overview
- Acronym
- LEILA75+
- Investigators
-
- Contacts
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General Design
- Study design
- Cohort
- Start - End Year
- 1997 - 2014
- General Information on Follow Up (profile, frequency)
-
Five follow-up assessments scheduled every 18 months. A final long-term follow-up was conducted 8 years after follow-up 5, for a total observation period of 16 years.
- Recruitment Target
-
- Individuals
- Number of Participants
- 1,265
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Paper
Riedel-Heller, S.G., Busse, A., Aurich, C., Matschinger, H., Angermeyer, M.C. Prevalence of dementia according to DSM-III-R and ICD-10. Results of the Leipzig Longitudinal Study of the Aged (LEILA75+) Part I. British Journal of Psychiatry (2018) 179, 250-254
PUBMED 11532803Timeline
Population
LEILA75 - Population
The population is made of community-dwelling individuals aged 75 years and over living in the community of Leipzig-South.
Selection Criteria
- Minimum age
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75
- Countries
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- Germany
- Territory
- Leipzig-South
- Supplementary Information about selection criteria
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Institutionalized individuals were included in the study by proportion, because in the study area residential homes were over-represented and nursing homes were underrepresented.
Sources of Recruitment
- General Population
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- Selected sample
- Specific Population
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- Other specific population : Institutionalized individuals.
- Supplementary Information
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Participants were identified by systematic random sampling from an age-ordered list provided by the official registry office for each of the seven sub-districts. Institutionalized individuals were included in the study by proportion. Sixty residential home residents and 132 nursing home residents were identified by systematic random sampling from an age-ordered list provided by the four institutions in the study area.
Sample Size
- Number of Participants
- 1,265
- Supplementary Information about selection criteria
-
Baseline: 1,265 participants
Follow-up 1: 742 participants
Follow-up 2: 610 participants
Follow-up 3: 483 participants
Follow-up 4: 375 participants
Follow-up 5: 313 participants
Follow-up 6: 181 participants
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | LEILA75 - Baseline |
|
1997 (January) | 1998 (June) | |
| 1 | LEILA75 - Follow-up 1 |
|
1998 (July) | 1999 (December) | |
| 2 | LEILA75 - Follow-up 2 |
|
2000 (January) | 2001 (June) | |
| 3 | LEILA75 - Follow-up 3 |
|
2001 (July) | 2002 (December) | |
| 4 | LEILA75 - Follow-up 4 |
|
2003 (January) | 2004 (June) | |
| 5 | LEILA75 - Follow-up 5 |
|
2004 (July) | 2005 (April) | |
| 6 | LEILA75 - Follow-up 6 |
|
2012 (July) | 2013 (December) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2020-02-05T11:07:47.343