1. Maelstrom Catalogue
  2. Individual Studies
  3. LSPIPSA-HCW

Longitudinal study on prevalence, incidence and persistence of SARS-CoV-2 antibodies in health care workers using home blood collection kits and a fully automated ELISA and ECLIA antibody assay

The objectives of this study are: 1. To compare home blood collection kit using a micro-tube or a dried blood spot. 2. To provide rates of previous and new infections with COVID-19 and re-infection rates in health care workers (HCWs). This should help to understand if immunity is durable and provides future resistance to COVID-19 infection.

Overview

Acronym
LSPIPSA-HCW
Investigators
Dr. Keith Jarvi
Mount Sinai Hospital
Contacts
Susan Lau
Mount Sinai Hospital

General Design

Study design
Cohort
Start - End Year
2020 - 2022
General Information on Follow Up (profile, frequency)
For the longitudinal participants, follow-up questionnaires were completed at 3, 6, 12 and 18 months following the initial assays; and 30 days after the completion of the vaccination. An identical process was followed for the serological testing 3, 6, 12 and 18 months following the initial assays; and 30 days after the completion of vaccination.
Recruitment Target
  • Individuals
Number of Participants
1,720
Number of Participants with Biological Samples
1,720
Supplementary information about number of participants
COVID-19 infected: 10 participants
COVID-19 negative and untested: 10 participants
Mount Sinai Hospital: 1200 Participants
Health Science North (Sudbury): 250 Participants
Sault Area Hospital (Sault Ste Marie): 250 Participants

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other
Yes
No
Not applicable
Don't know

Timeline

Populations

LSPIPSA-HCW - COVID-19 infected
The population is composed of COVID-19 positive and recovered patients from Mount Sinai Hospital with a previous COVID-19 positive test by naso-pharyngeal swab.

Selection Criteria

Countries
  • Canada
Canadian Provinces
  • Ontario
Territory
Toronto
Health Status
  • COVID-19 positive and recovered

Sources of Recruitment

Specific Population
  • Clinic patients
Supplementary Information
COVID-19 positive and recovered patients are recruited from Mount Sinai Hospital patient population. Patients are approached to participate, then they are provided with the consent form and information on how to contact the research coordinator for this study. The COVID-19 infected patients participate in this study after they have recovered from the infection and are no longer infected (not hospitalized patients).

Sample Size

Number of Participants
10
Number of Participants with Biological Samples
10

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 LSPIPSA-HCW - COVID-19 infected - ELISA capillary blood samples
  • Biosamples
  • Blood
2020 (September) Ongoing
LSPIPSA-HCW - COVID-19 negative and untested
The population is composed of health care workers at the Mount Sinai Hospital, COVID-19 untested or previously negative.

Selection Criteria

Countries
  • Canada
Canadian Provinces
  • Ontario
Territory
Toronto
Health Status
  • COVID-19 untested or previously negative

Sources of Recruitment

Specific Population
  • Members of an association
Supplementary Information
Participants will be recruited by word of mouth from within the health care workers at the Mount Sinai Hospital.

Sample Size

Number of Participants
10
Number of Participants with Biological Samples
10

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 LSPIPSA-HCW - COVID-19 negative and untested - ELISA capillary blood samples
  • Biosamples
  • Blood
2020 (September) Ongoing
LSPIPSA-HCW - Longitudinal
The population is composed of Mount Sinai Hospital (MSH), Sault Area Hospital and Health Sciences North (Sudbury) health care workers.

Selection Criteria

Countries
  • Canada
Canadian Provinces
  • Ontario
Other Criteria
Exclusion: Present symptoms compatible with COVID-19 infections and for those with confirmed COVID-19 positive had a negative NP swab test for COVID-19 (recovered from COVID-19)

Sources of Recruitment

Specific Population
  • Members of an association
Supplementary Information
Information about this study was electronically distributed to the health care workers (HCWs) at the Mount Sinai Hospital, Sault Area Hospital and Health Sciences North (Sudbury). Volunteers will contact the research coordinator and will be eligible to participate in the study if they are able to provide the blood samples and if they are willing to complete the entire 18 months of the study.

Sample Size

Number of Participants
1,700
Number of Participants with Biological Samples
1,700

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 LSPIPSA-HCW - Longitudinal - Blood collection
  • Questionnaires
  • Biosamples
  • Blood
2020 (September) Ongoing
1 LSPIPSA-HCW - Longitudinal - 3 months follow-up
  • Questionnaires
  • Biosamples
  • Blood
2020 (December) Ongoing
2 LSPIPSA-HCW - Longitudinal - 6 months follow-up
  • Questionnaires
  • Biosamples
  • Blood
2021 (March) Ongoing
3 LSPIPSA-HCW - Longitudinal - 12 months follow-up
  • Questionnaires
  • Biosamples
  • Blood
2021 (September) Ongoing
4 LSPIPSA-HCW - Longitudinal - 18 months follow-up
  • Questionnaires
  • Biosamples
  • Blood
2022 (March) 2022
5 LSPIPSA-HCW - Longitudinal - 1 month post-vaccination
  • Questionnaires
  • Biosamples
  • Blood
2021 (February) 2021

Participating Studies

Acronym Name Study design Countries

Harmonization Initiatives Included

Acronym Name

Datasets

Name Data Collection Events Variables

Areas of Information Collected

Socio-demographic and economic characteristics
Death
Lifestyle and behaviours
Physical measures and assessments
Birth, pregnancy and reproductive health history
Laboratory measures
Perception of health, quality of life, development and functional limitations
Cognition, personality and psychological measures and assessments
Diseases
Life events, life plans, beliefs and values
Symptoms and signs
Preschool, school and work life
Medication and supplements
Social environment and relationships
Non-pharmacological interventions
Physical environment
Health and community care services utilization
Administrative information

Variables Content Summary

Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected

Networks

Acronym Name Harmonization Initiatives Individual Studies
Last Update: 2024-02-27T14:39:38.857