Multi-Ethnic Study of Atherosclerosis - Neighbourhood
- The overall goal of the MESA Neighbourhood study are to examine longitudinal associations of specific features of neighborhood environments (and changes in neighborhood environments) with changes in key risk factors over time and with incident cardiovascular events, and to investigate the contributions of neighborhoods to race/ethnic and socioeconomic differences in cardiovascular risk. The specific aims are:
- To examine associations of specific neighborhood characteristics and changes in neighborhood characteristics (including measures of access to healthy foods, walkability and urban design, access to recreational resources, and neighborhood stressors) with changes in diet, physical activity, and body weight over time;
- To examine associations of neighborhood characteristics and changes in neighborhood characteristics with incident diabetes and hypertension as well as with changes over time in continuous measures of insulin resistance and blood pressure;
- To examine associations of neighborhood characteristics with incident fatal and non fatal cardiovascular events;
- To investigate the contribution of neighborhood environments to race/ethnic and socioeconomic differences in longitudinal changes in risk factors and incident disease; and
- To establish and maintain a rich database of longitudinal environmental exposures for MESA participants that can be used in future gene environment interaction studies.
Overview
- Acronym
- MESA Neighbourhood
- Website
- MESA Neighbourhood
- Investigators
-
Dr. Latetia V. MooreNational Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2000 -
- General Information on Follow Up (profile, frequency)
-
Participants were assessed 5 times. Baseline was in 7/2000-8/2002; Follow-up 1 in 7/2002-2/2004; Follow-up 2 in 1/2004-9/2005; Follow-up 3 in 9/2005-5/2007; Follow-up 4 in 4/2010-2/2012.
- Recruitment Target
-
- Individuals
- Number of Participants
- 6,191
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Paper
Diez Roux, Ana V. et al. "The Impact Of Neighborhoods On CV Risk". Global Heart 11.3 (2016): 353-363.
PUBMED 27741982Timeline
Population
MESA Neighbourhood population
The population consisted of individuals aged 45 to 84 years from various ethnic backgrounds.
Selection Criteria
- Minimum age
-
45
- Maximum age
-
84
- Countries
-
- United States of America
- Territory
- Baltimore; Chicago; Forsyth County, NC; Los Angeles; New York; and St Paul, MN
- Health Status
-
- Participants with known clinical cardiovascular disease were excluded from recruitment (physician diagnosed heart attack, angina or taking nitroglycerin, stroke, TIA, heart failure, current atrial fibrillation, undergone procedures related to CVD (CABG, angioplasty, valve replacement, pacemaker, surgery of heart or arteries).
Sources of Recruitment
- General Population
-
- Selected sample
- Random digit dialing
- Supplementary Information
-
The sampling frame and methods for potential participants varied by field center, depending on the nature of the local sampling frame and logistics. The sampling unit was the household, and all eligible participants who resided in a single household were recruited for the study.
Sample Size
- Number of Participants
- 6,191
- Supplementary information about number of participants
-
6814 participants recruited in full MESA study, 6191 participants in MESA Neighborhood study
Baseline: 6191 participants
Follow-up 1: 6083 participants
Follow-up 2: 5920 participants
Follow-up 3: 5693 participants
Follow-up 4: 4637 participants
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | MESA Neighbourhood - Baseline |
|
|
2000 (July) | 2002 (August) |
| 1 | MESA Neighbourhood - Follow-up 1 |
|
|
2002 (July) | 2004 (February) |
| 2 | MESA Neighbourhood - Follow-up 2 |
|
|
2004 (January) | 2005 (September) |
| 3 | MESA Neighbourhood - Follow-up 3 |
|
|
2005 (September) | 2007 (May) |
| 4 | MESA Neighbourhood - Follow-up 4 |
|
|
2010 (April) | 2012 (February) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2023-08-10T18:19:22.822