Northern Sweden MONItoring of trends and determinants in CArdiovascular disease (MONICA)

The Northern Sweden MONICA Study is a cohort within Northern Sweden Health and Disease Study (NSHDS). It started with the WHO MONICA Study in 1985. The purpose was to monitor trends in mortality and morbidity in cardiovascular disease and relate them to trends in risk factors. Since 1985 over 21,000 strictly validated stroke events and 19,000 myocardial infarctions have been included in two registers. During the same period, eight population based surveys have been taking place, the latest in 2022. The participation rates have been 47-81%. Subjects donated samples to Biobanken norr.

Overview

Acronym
NSHDS-MONICA
Website
NSHDS-MONICA
Contacts
The Section of Biobank and Registry Support
Umeå University

General Design

Study design
Cohort
Start - End Year
1986 -
General Information on Follow Up (profile, frequency)
Population surveys have been performed in 1986, 1990, 1994, 1999, 2004, 2009, 2014 and 2022. In 1999, all people invited to any of the three previous population surveys were re-invited for follow-up
Recruitment Target
  • Individuals
Number of Participants
13,800
Supplementary Information
The Northern Sweden MONICA Project has collected repeated cross-sectional as well as longitudinal data.

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other

Marker Papers

Späth F et al. Cohort Profile: The Northern Sweden Health and Disease Study (NSHDS). Int J Epidemiol. 2024 Dec 16;54(1):dyaf004

PUBMED 39899988

Timeline

Populations

NSHDS-MONICA - Cohort 1
The population is composed of adults aged 25 to 64 years old who were living in Norrbotten and Västerbotten county in 1986.

Selection Criteria

Minimum age
25
Maximum age
64
Countries
  • Sweden
Territory
Västerbotten and Norrbotten counties

Sources of Recruitment

General Population
  • Selected sample
Supplementary Information
A stratified randomized selection procedure by age and sex (250 persons in each sex/10-year age stratum) was used to recruit participants.

Sample Size

Number of Participants
1,625

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 NSHDS-MONICA - Cohort 1 - Baseline
  • Questionnaires
  • Physical measures
  • Biosamples
  • Administrative databases
  • Blood
1986 (January) 1986 (April)
1 NSHDS-MONICA - Cohort 1 - Follow-up
  • Questionnaires
  • Physical measures
  • Biosamples
  • Administrative databases
  • Blood
1999 (January) 1999 (April)
NSHDS-MONICA - Cohort 2
The population is composed of adults aged 25 to 64 years old who were living in Norrbotten and Västerbotten county in 1990.

Selection Criteria

Minimum age
25
Maximum age
64
Countries
  • Sweden
Territory
Västerbotten and Norrbotten counties

Sources of Recruitment

General Population
  • Selected sample
Supplementary Information
A stratified randomized selection procedure by age and sex (250 persons in each sex/10-year age stratum) was used to recruit participants.

Sample Size

Number of Participants
1,583

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 NSHDS-MONICA - Cohort 2 - Baseline
  • Questionnaires
  • Physical measures
  • Biosamples
  • Administrative databases
  • Blood
1990 (January) 1990 (April)
1 NSHDS-MONICA - Cohort 2 - Follow-up
  • Questionnaires
  • Physical measures
  • Biosamples
  • Blood
1999 (January) 1999 (April)
NSHDS-MONICA - Cohort 3
The population is composed of adults aged 25 to 74 years old who were living in Norrbotten and Västerbotten county in 1994.

Selection Criteria

Minimum age
25
Maximum age
74
Countries
  • Sweden
Territory
Västerbotten and Norrbotten counties

Sources of Recruitment

General Population
  • Selected sample
Supplementary Information
A stratified randomized selection procedure by age and sex (250 persons in each sex/10-year age stratum) was used to recruit participants.

Sample Size

Number of Participants
1,921

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 NSHDS-MONICA - Cohort 3 - Baseline
  • Questionnaires
  • Physical measures
  • Biosamples
  • Administrative databases
  • Blood
1994 (January) 1994 (April)
1 NSHDS-MONICA - Cohort 3 - Follow-up
  • Questionnaires
  • Physical measures
  • Biosamples
  • Blood
1999 (January) 1999 (April)
NSHDS-MONICA - Cohort 4
The population is composed of adults aged 25 to 74 years old who were living in Norrbotten and Västerbotten county in 1999.

Selection Criteria

Minimum age
25
Maximum age
74
Countries
  • Sweden
Territory
Västerbotten and Norrbotten counties

Sources of Recruitment

General Population
  • Selected sample
Supplementary Information
A stratified randomized selection procedure by age and sex (250 persons in each sex/10-year age stratum) was used to recruit participants.

Sample Size

Number of Participants
1,823

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 NSHDS-MONICA - Cohort 4 - Baseline
  • Questionnaires
  • Physical measures
  • Biosamples
  • Administrative databases
  • Blood
1999 (January) 1999 (April)
NSHDS-MONICA - Cohort 5
The population is composed of adults aged 25 to 74 years old who were living in Norrbotten and Västerbotten county in 2004.

Selection Criteria

Minimum age
25
Maximum age
74
Countries
  • Sweden
Territory
Västerbotten and Norrbotten counties

Sources of Recruitment

General Population
  • Selected sample
Supplementary Information
A stratified randomized selection procedure by age and sex (250 persons in each sex/10-year age stratum) was used to recruit participants.

Sample Size

Number of Participants
1,905

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 NSHDS-MONICA - Cohort 5 - Baseline
  • Questionnaires
  • Physical measures
  • Biosamples
  • Administrative databases
  • Blood
2004 (January) 2004 (April)
NSHDS-MONICA - Cohort 6
The population is composed of adults aged 25 to 74 years old who were living in Norrbotten and Västerbotten county in 2009.

Selection Criteria

Minimum age
25
Maximum age
74
Countries
  • Sweden
Territory
Västerbotten and Norrbotten counties

Sources of Recruitment

General Population
  • Selected sample
Supplementary Information
A stratified randomized selection procedure by age and sex (250 persons in each sex/10-year age stratum) was used to recruit participants.

Sample Size

Number of Participants
1,729

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 NSHDS-MONICA - Cohort 6 - Baseline
  • Questionnaires
  • Physical measures
  • Biosamples
  • Administrative databases
  • Blood
2009 (January) 2009 (April)
NSHDS-MONICA - Cohort 7
The population is composed of adults aged 25 to 74 years old who were living in Norrbotten and Västerbotten county in 2014.

Selection Criteria

Minimum age
25
Maximum age
74
Countries
  • Sweden
Territory
Västerbotten and Norrbotten counties

Sources of Recruitment

General Population
  • Selected sample
Supplementary Information
A stratified randomized selection procedure by age and sex (250 persons in each sex/10-year age stratum) was used to recruit participants.

Sample Size

Number of Participants
1,575

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 NSHDS-MONICA - Cohort 7 - Baseline
  • Questionnaires
  • Physical measures
  • Biosamples
  • Administrative databases
  • Blood
2014 (January) 2014 (April)
NSHDS-MONICA - Cohort 8
The population is composed of adults aged 25 to 74 years old who were living in Norrbotten and Västerbotten county in 2022.

Selection Criteria

Minimum age
25
Maximum age
74
Countries
  • Sweden
Territory
Västerbotten and Norrbotten counties

Sources of Recruitment

General Population
  • Selected sample
Supplementary Information
A stratified randomized selection procedure by age and sex (250 persons in each sex/10-year age stratum) was used to recruit participants.

Sample Size

Number of Participants
1,175

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 NSHDS-MONICA - Cohort 8 - Baseline
  • Questionnaires
  • Physical measures
  • Biosamples
  • Administrative databases
  • Blood
2022 (January) 2022 (April)

Participating Studies

Acronym Name Study design Countries

Harmonization Initiatives Included

Acronym Name

Datasets

Name Data Collection Events Variables

Areas of Information Collected

Socio-demographic and economic characteristics
Death
Lifestyle and behaviours
Physical measures and assessments
Birth, pregnancy and reproductive health history
Laboratory measures
Perception of health, quality of life, development and functional limitations
Cognition, personality and psychological measures and assessments
Diseases
Life events, life plans, beliefs and values
Symptoms and signs
Preschool, school and work life
Medication and supplements
Social environment and relationships
Non-pharmacological interventions
Physical environment
Health and community care services utilization
Administrative information

Variables Content Summary

Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected

Networks

Acronym Name Harmonization Initiatives Individual Studies
Last Update: 2026-03-05T08:20:09.946