The Malmö Offspring Study

The general aim of this study is to generate the information on how diseases are spread within families, not only through genetic inheritance but also through lifestyle, social patterns, and health habits.

Overview

Acronym
MOS
Website
MOS
Investigators
Prof. Olle Melander
Lund university
Prof. Peter Nilsson
Lunds University
Contacts
Prof. Olle Melander
Lund university
Data Manager Anders Dahlin
Lund University
Prof. Peter Nilsson
Lunds University

General Design

Study design
Cohort
Start - End Year
2013 - 2021
General Information on Follow Up (profile, frequency)
After baseline, participants were followed-up in 2016, 2018 and 2019.
Recruitment Target
  • Individuals
Number of Participants
5,259
Number of Participants with Biological Samples
5,259
Supplementary information about number of participants
Follow-up 1 (2016): 2644 participants
Follow-up 2 (2018): 4225 participants
Follow-up 3 (2019): 4225 participants
Supplementary Information
MOS is family-based cohort study with register-based follow-up by use of the personal identification system in Sweden.

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other

Marker Papers

Brunkwall L, Jönsson D, Ericson U, et al. The Malmö Offspring Study (MOS): design, methods and first results. Eur J Epidemiol. 2021 Jan;36(1):103-116.

PUBMED 33222051

Jönsson D, Orho-Melander M, Demmer RT, et al. Periodontal disease is associated with carotid plaque area: the Malmö Offspring Dental Study (MODS). J Intern Med. 2020 Mar;287(3):301-309.

PUBMED 31633250

Timeline

Population

MOS population
The population is composed of adults 18 years and above and who are children and grandchildren of the participants in the Malmö Diet and Cancer study.

Selection Criteria

Minimum age
18
Countries
  • Sweden
Territory
Skåne
Other Criteria
Children (G2) and grandchildren (G3) to index individuals in G1(Malmö Diet and Cancer Study) are recruited. Individuals with difficulties in understanding the Swedish language are not included
Supplementary Information about selection criteria
The first 150 participants in this study were recruited based on that their first-generation index individual (G1) had an early cardiac event.

Sources of Recruitment

Other Recruitment Target
Children (G2) and grandchildren (G3) to participants from Malmö Diet Cancer study(MDC)

Sample Size

Number of Participants
5,259
Number of Participants with Biological Samples
5,259

Data Collection Events

# Name Data sources Data sources - Biosamples Start End
0 MOS - Baseline
  • Questionnaires
  • Cognitive measures
  • Physical measures
  • Biosamples
  • Administrative databases
  • Other : The Malmö Offspring Dental Study(MODS)
  • Blood
  • Urine
  • Saliva
  • Buccal cells
  • Other : Ultrasound of the arteria carotis, fecal samples and DNA
2013 (March) Ongoing
1 MOS - Follow-up 1
  • Administrative databases
2016 2016
2 MOS - Follow-up 2
  • Administrative databases
2018 2018
3 MOS - Follow-up 3
  • Administrative databases
2019 2019

Participating Studies

Acronym Name Study design Countries

Harmonization Initiatives Included

Acronym Name

Datasets

Name Data Collection Events Variables

Areas of Information Collected

Socio-demographic and economic characteristics
Death
Lifestyle and behaviours
Physical measures and assessments
Birth, pregnancy and reproductive health history
Laboratory measures
Perception of health, quality of life, development and functional limitations
Cognition, personality and psychological measures and assessments
Diseases
Life events, life plans, beliefs and values
Symptoms and signs
Preschool, school and work life
Medication and supplements
Social environment and relationships
Non-pharmacological interventions
Physical environment
Health and community care services utilization
Administrative information

Variables Content Summary

Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected

Networks

Acronym Name Harmonization Initiatives Individual Studies
Last Update: 2023-08-10T18:18:55.066