Maelstrom Research

Nicotine Dependence in Teens Study

The Nicotine Dependence in Teens (NDIT) Study is a prospective cohort investigation of adolescents conducted in Montreal.

NDIT aimed to describe the natural course of cigarette smoking and nicotine dependence (ND) in novice smokers, to measure the intensity of ND symptoms in relation to cigarette smoking and to investigate the importance of a wide range of individual-level and contextual factors in the initiation of smoking and ND.

In addition to its primary objectives, NDIT has embedded studies on obesity, blood pressure, physical activity team sports, sedentary behaviour, diet, genetics, alcohol use, use of illicit drugs, second-hand smoke, gambling, sleep and mental health.

Overview

Acronym

NDIT

Website

NDIT

Investigators

Dr. Gilles Paradis

McGill University

Dr. Rachel Tyndale

University of Toronto

MD. Joseph DiFranza

University of Massachusetts Medical School

Dr. James Hanley

McGill University

Dr. André Gervais

Direction de santé publique de Montréal

Contacts

Jennifer O'Loughlin

CHUM Research Centre

General Design

Study design

Cohort

Start - End Year

1999 - 2013

General Information on Follow Up (profile, frequency)

Baseline self-report questionnaires were completed during class time at school in autumn 1999 in nine schools and in autumn 2000 in one school. Follow-up questionnaires were completed every 3 months thereafter during the 10-month school year for the next 5 years (1999–2005) until NDIT participants completed grade 11 and graduated from high school, for a total of 20 survey cycles during high school. In 2007–08, when NDIT participants were age 20 years on average, they completed self-report questionnaires that were mailed to their homes with a stamped addressed return envelope (i.e. survey cycle 21). Finally, NDIT participants completed a self-report questionnaire administered in the NDIT research offices in 2011–12 when they were age 24 years on average (i.e. survey cycle 22).

Recruitment Target

Individuals

Number of Participants

1,294

Number of Participants with Biological Samples

962

Access

General Information

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other

Yes

Not applicable

Don't know

Marker Papers

O'Loughlin J, Dugas EN, et al. Cohort Profile: The Nicotine Dependence in Teens (NDIT) Study. International journal of epidemiology, 2014; pii: dyu135.

PUBMED 25022274

Supplementary Information

Access to data and biological data is available to university-appointed or affiliated investigators and to masters, doctoral and postdoctoral students, through their primary supervisor (www.nditstudy.ca).

Timeline

Population

During cycle 1, 1195 NDIT participants provided anthropometric and blood pressure measures.

Start Date

1999 (September)

End Date

1999 (September)

Data sources

Physical measures

The main source of data was self-report questionnaires administered in class at school every 3 months from grade 7 to grade 11 (1999–2005), for a total of 20 survey cycles during high school.

Start Date

1999 (September)

End Date

2004 (June)

Data sources

Questionnaires

523 blood samples were collected during cycle 11 for deoxyribonucleic acid (DNA) extraction.

Start Date

2002 (March)

End Date

2002 (March)

Data sources

Biosamples

Data sources - Biosamples

Blood

During cycle 12, 10 school questionnaires were completed by school administrator and/or teachers.

Start Date

2002 (June)

End Date

2002 (June)

Data sources

Questionnaires

During cycle 12, 955 NDIT participants provided anthropometric and blood pressure measures.

Start Date

2002 (June)

End Date

2002 (June)

Data sources

Physical measures

Direct observations on tolerance to smoking in school neighbourhoods (i.e. environmental scans) were completed during cycle 16.

Start Date

2003 (June)

End Date

2003 (June)

Data sources

Other : Direct observation

During cycle 19, 804 NDIT participants provided anthropometric and blood pressure measures.

Start Date

2004 (March)

End Date

2004 (March)

Data sources

Physical measures

Questionnaires were completed after graduation from high school in 2007–08 (survey cycle 21) when participants were aged 20 years on average.

During cycle 21, 336 NDIT participants provided saliva samples for deoxyribonucleic acid (DNA) extraction.

Start Date

2007

End Date

2008

Data sources

Questionnaires
Biosamples

Data sources - Biosamples

Saliva

597 mothers completed the mother questionnaire.

479 fathers completed the father questionnaire.

648 mothers/fathers completed the questionnaire about NDIT participant.

822 parents provided saliva samples for deoxyribonucleic acid (DNA) extraction.

Start Date

2009

End Date

2010

Data sources

Questionnaires
Biosamples

Data sources - Biosamples

Saliva

During cycle 22, 103 NDIT participants provided saliva samples for deoxyribonucleic acid (DNA) extraction and 236 smoking participants provided saliva samples for cotinine analysis.

363 participants completed the diet history questionnaire.

781 NDIT participants provided anthropometric and blood pressure measures.

341 NDIT participants wore accelerometers to collect an objective measure of physical activity.

Start Date

2011

End Date

2012

Data sources

Questionnaires
Physical measures
Biosamples

Data sources - Biosamples

Saliva

NDIT population

The population is composed of students recruited in 1999–2000 from all grade 7 classes in a convenience sample of 10 high schools in Montreal, Canada.

Selection Criteria

Countries

Canada

Canadian Provinces

Quebec

Territory

Montreal

Other Criteria

Grade 7 students.

Sources of Recruitment

General Population

Volunteer enrolment

Sample Size

Number of Participants: 1,294
Number of Participants with Biological Samples: 962
Supplementary information about number of participants: Cycle 1: Questionnaire (1267 participants) and physical measures (1195 participants)

Cycle 2: Questionnaire (1198 participants)

Cycle 3: Questionnaire (1191 participants)

Cycle 4: Questionnaire (545 participants)

Cycle 5: Questionnaire (1104 participants)

Cycle 6: Questionnaire (1101 participants)

Cycle 7: Questionnaire (960 participants)

Cycle 8: Questionnaire (982 participants)

Cycle 9: Questionnaire (1022 participants)

Cycle 10: Questionnaire (995 participants)

Cycle 11: Questionnaire (972 participants) and blood samples (523 participants)

Cycle 12: Questionnaire (987 participants), physical measures (955 participants) and 10 school questionnaires completed by school administrator and/or teacher

Cycle 13: Questionnaire (914 participants)

Cycle 14: Questionnaire (906 participants)

Cycle 15: Questionnaire (904 participants)

Cycle 16: Questionnaire (887 participants) and environmental scans (171)

Cycle 17: Questionnaire (871 participants)

Cycle 18: Questionnaire (853 participants)

Cycle 19: Questionnaire (844 participants) and physical measures (804 participants)

Cycle 20: Questionnaire (840 participants)

Cycle 21: Questionnaire (880 participants) and saliva samples (336 participants)

Parent questionnaires: Mother questionnaire (597 mothers), father questionnaire (479 fathers), questionnaire about NDIT participants (648 mothers/fathers) and saliva samples (822 parents)

Cycle 22: Questionnaire (858 participants), saliva samples (103 participants), diet history questionnaire (363 participants), physical measures (781 participants), wearing accelerometers (341 participants) and saliva samples for cotinine (236 smoking participants)

Data Collection Events

#	Name	Data sources	Data sources - Biosamples	Start	End
0	NDIT - Physical measures 1	Physical measures		1999 (September)	1999 (September)
1	NDIT - Questionnaire follow-up during high school	Questionnaires		1999 (September)	2004 (June)
2	NDIT - Blood samples 1	Biosamples	Blood	2002 (March)	2002 (March)
3	NDIT - School questionnaire	Questionnaires		2002 (June)	2002 (June)
4	NDIT - Physical measures 2	Physical measures		2002 (June)	2002 (June)
5	NDIT - Environmental scans	Other : Direct observation		2003 (June)	2003 (June)
6	NDIT - Physical measures 3	Physical measures		2004 (March)	2004 (March)
7	NDIT - 3 years post high school	Questionnaires Biosamples	Saliva	2007	2008
8	NDIT - Parent questionnaire	Questionnaires Biosamples	Saliva	2009	2010
9	NDIT - 6 years post high school	Questionnaires Physical measures Biosamples	Saliva	2011	2012

Participating Studies

Acronym	Name	Study design	Countries

Harmonization Initiatives Included

Acronym	Name

Datasets

Search Variables

Name	Data Collection Events	Variables

Variables Content Summary

Areas of Information Collected per per Population and Data Collection Event

Networks

Acronym	Name	Harmonization Initiatives	Individual Studies

Last Update: 2023-09-26T14:05:15.848

Nicotine Dependence in Teens Study

Overview

General Design

Access

Marker Papers

Supplementary Information

Documents

Timeline

Population

Selection Criteria

Sources of Recruitment

Sample Size

Documents

Data Collection Events

Participating Studies

Harmonization Initiatives Included

Datasets

Areas of Information Collected

Variables Content Summary

Areas of Information Collected

Areas of Information Collected per per Population and Data Collection Event

Networks

Nicotine Dependence in Teens Study

Overview

Gilles Paradis

Rachel Tyndale

Joseph DiFranza

James Hanley

André Gervais

Jennifer O'Loughlin

General Design

Access

Marker Papers

Supplementary Information

Documents

Timeline

Population

NDIT - Physical measures 1

NDIT - Questionnaire follow-up during high school

NDIT - Blood samples 1

NDIT - School questionnaire

NDIT - Physical measures 2

NDIT - Environmental scans

NDIT - Physical measures 3

NDIT - 3 years post high school

NDIT - Parent questionnaire

NDIT - 6 years post high school

Selection Criteria

Sources of Recruitment

Sample Size

Documents

Data Collection Events

Participating Studies

Harmonization Initiatives Included

Datasets

Areas of Information Collected

Variables Content Summary

Areas of Information Collected

Areas of Information Collected per per Population and Data Collection Event

Networks