Ottawa and Kingston Birth Cohort
- The purposes of the Ottawa and Kingston Birth Cohort were to:
- collect epidemiologic information and biological specimens prospectively to study exposures or risk factors and their association with adverse pregnancy outcomes;
- serve as a repository of maternal and infant genetic and epidemiologic information by creating the largest maternal and fetal/infant biobank in Canada for use by future investigators.
Overview
- Acronym
- OaK Birth Cohort
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2002 - 2009
- General Information on Follow Up (profile, frequency)
-
After recruitment, mothers were followed-up until birth.
- Recruitment Target
-
- Families
- Number of Participants
- 10,260
- Number of Participants with Biological Samples
- 9,416
- Supplementary information about number of participants
-
Mothers: 8085 participants
Children: 2175 participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
- By contacting the study representative: Clinical Research Program Manager Alysha Harvey (Ottawa Hospital Research Institute)
Sector of research
| Possible Access to Data | Possible Access to Biosamples | |
| Investigators from the public sector | ||
| Investigators from the private sector | ||
| Investigators from not-for-profit organization |
Restrictions on use of the data and samples, based upon existing REB approval and associated limitations. No genetic testing may be performed on the samples.
Transfer
| Possible Access to Data | Possible Access to Biosamples | |
| Can leave the study facility | ||
| Can leave the country |
Cost
| Possible Access to Data | Variable Cost |
| Possible Access to Biosamples | Variable Cost |
Fees are dependent on the amount of work required to prepare the data or samples, depending on which elements are being requested.
Cost reduction for co-analyses
| Possible Access to Data | |
| Possible Access to Biosamples |
A publication policy exists for publishing work related to the data and/or samples. More information is available upon request.
Marker Paper
Walker MC, Finkelstein S.A., Rennicks White R., Shachkins S., Smith G.N., Wen S.W., Rodger M. The Ottawa And Kingston (Oak) Birth Cohort: Development And Achievements. Journal of Obstetrics and gynaecology Canada 2011 Nov;33(11):1124-33.
PUBMED 22082786Timeline
Populations
OaK Birth Cohort - Mothers
The population is composed of women who were in weeks 12 to 20 of an expected singleton or twin pregnancy and were receiving prenatal care from a physician or midwife within the study region.
Selection Criteria
- Gender
-
Women only
- Pregnant Women
-
- First trimester
- Second trimester
- Countries
-
- Canada
- Canadian Provinces
-
- Ontario
- Territory
- Ottawa and Kingston
Sources of Recruitment
- General Population
-
- Volunteer enrolment
- Specific Population
-
- Clinic patients
- Participants from Existing Studies
-
- Folic Acid in Second Trimester study
- Thrombophilia and Intrauterine Growth REStriction Study
- Folic Acid Supplementation in Early Second Trimester and Risk of Pre-Eclampsia study
- Supplementary Information
-
Participants were recruited from the Ottawa Hospital and Kingston General Hospital during prenatal care or ultrasound visits. Posters and brochures in both official languages were also distributed to the offices of obstetricians and family physicians within the study catchment area.
Sample Size
- Number of Participants
- 8,085
- Number of Participants with Biological Samples
- 7,241
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | OaK Birth Cohort - Mothers - Phase I |
|
|
2002 (October) | 2009 (April) |
| 1 | OaK Birth Cohort - Mothers - Phase II |
|
|
2003 (February) | 2009 (November) |
OaK Birth Cohort - Children
The population is composed of the newborn children of participating mothers.
Selection Criteria
- Newborns
- Countries
-
- Canada
- Canadian Provinces
-
- Ontario
- Territory
- Ottawa and Kingston
Sources of Recruitment
- Specific Population
-
- Other specific population : Children of women already included in the study.
Sample Size
- Number of Participants
- 2,175
- Number of Participants with Biological Samples
- 2,175
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | OaK Birth Cohort - Children - Phase II |
|
|
2003 (February) | 2009 (November) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2024-02-27T15:28:51.528