Prospective Investigation of the Vasculature in Uppsala Seniors
The primary aim of the PIVUS study was to study the pathogenesis of atherosclerosis and its related diseases by investigating the predictive power of different measurements of endothelial function and arterial compliance regarding future cardiovascular events. As secondary aims, the study also included measurements of cardiac function and structure by ultrasound and MRI, evaluation of atherosclerosis by ultrasound and MRI, 7-day food intake recordings, detailed ECG analysis, cardiovascular autonomic function, body composition by DXA, DNA analysis and lung function, cognitive function tests, as well as a number of biochemical markers.
Overview
- Acronym
- PIVUS
- Website
- PIVUS
- Investigators
-
- Contacts
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General Design
- Study design
- Cohort
- Start - End Year
- 2001 - 2014
- General Information on Follow Up (profile, frequency)
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Participants were followed-up twice, at 5-year intervals.
- Recruitment Target
-
- Individuals
- Number of Participants
- 1,016
- Number of Participants with Biological Samples
- 1,016
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
http://www.medsci.uu.se/pivus/publications/
Marker Paper
Lind L, Fors N, Hall J, Marttala K, Stenborg A. A comparison of three different methods to evaluate endothelium-dependent vasodilation in the elderly: the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study. Arterioscler Thromb Vasc Biol. 2005;25(11):2368-2375.
PUBMED 16141402Timeline
Population
PIVUS population
The population consisted of subjects aged 70 years, who were living in the community of Uppsala, Sweden, chosen from the register of community living and invited to participate in a randomized order.
Selection Criteria
- Minimum age
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70
- Maximum age
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70
- Countries
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- Sweden
- Territory
- Uppsala
Sources of Recruitment
- General Population
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- Selected sample
- Supplementary Information
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All individuals aged 70 years living in the community of Uppsala, Sweden were eligible to participate. Participants were chosen randomly from the register of community living and received an invitation letter within 2 months of their 70th birthday.
Sample Size
- Number of Participants
- 1,016
- Number of Participants with Biological Samples
- 1,016
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | PIVUS – 70 years |
|
|
2001 (April) | 2004 (June) |
| 1 | PIVUS – 75 years |
|
|
2006 (March) | 2009 (July) |
| 2 | PIVUS – 80 years |
|
|
2011 (April) | 2014 (June) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
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Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2020-10-28T12:49:21.480