The Psychiatric arm of the population-based CoLaus|PsyCoLaus study
The CoLaus|PsyCoLaus investigation should allow us to address three main questions:
* Do mental disorders increase vulnerability to CVRF and CVD?
* Do CVRF and CVD or their drug treatment promote the development of mental disorders?
* Do CVRF/CVD and mental disorders share common pathogenetic processes?
The specific objectives of the PsyCoLaus investigation are to:
1. Establish the lifetime and 12-month prevalence of threshold (DSM-IV) and subthreshold psychiatric syndromes and migraine in residents of the city of Lausanne, who were 35-75 years old in 2003;
2. Test the validity of postulated definitions for subthreshold psychiatric disorders, and especially mood and anxiety syndromes as well as the concept of atypical depression using comorbidity patterns, risk of suicidal attempts, health service use, social functioning (Global Assessment of Function scores, GAF) and family history as validator variables;
3. Determine the association between the lifetime history of major depressive disorder (MDD), and other psychiatric disorders and risk factors for CVD; and
4. Identify genetic variants and biomarkers that can modify the risk for various psychiatric disorders and for comorbid CVD and psychiatric disorders.
Overview
- Acronym
- PsyCoLaus
- Website
- PsyCoLaus
- Investigators
-
- Contacts
-
General Design
- Study design
- Cohort
- Start - End Year
- 2004 -
- General Information on Follow Up (profile, frequency)
-
Participants were first seen in 2004 and were followed-up in 2009, 2015 and 2018.
- Recruitment Target
-
- Individuals
- Number of Participants
- 5,125
- Supplementary information about number of participants
-
Baseline: 3728 participants
Follow-up 1: 4006 participants
Follow-up 2: 3666 participants
Follow-up 3: 2632(ongoing) participants
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Marker Paper
Preisig M, Waeber G, Vollenweider P, Bovet P, Rothen S, Vandeleur C, Guex P, Middleton L, Waterworth D, Mooser V, Tozzi F, Muglia P. The PsyCoLaus study: methodology and characteristics of the sample of a population-based survey on psychiatric disorders and their association with genetic and cardiovascular risk factors. BMC Psychiatry. 2009 Mar 17;9:9.
PUBMED 19292899Timeline
Population
PsyCoLaus population
The population is composed of participants from the Colaus study, which were selected residents of the city of Lausanne (Switzerland) according to the civil register, who were 35-75 years old in 2003.
Selection Criteria
- Minimum age
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35
- Maximum age
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75
- Countries
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- Switzerland
- Territory
- Lausanne
- Other Criteria
- Be sufficiently fluent in French or English
Sources of Recruitment
- Participants from Existing Studies
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- CoLaus Study: Cohorte Lausannoise
Sample Size
- Number of Participants
- 5,125
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | PsyCoLaus - Baseline |
|
2004 (January) | 2008 (April) | |
| 1 | PsyCoLaus -Follow-up 1 |
|
2009 (January) | 2013 (April) | |
| 2 | PsyCoLaus -Follow-up 2 |
|
2015 (January) | 2018 (April) | |
| 3 | PsyCoLaus -Follow-up 3 |
|
2018 (January) | 2021 (April) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2021-05-10T15:44:02.523