Screening Across the Lifespan Twin Study

Overview

Acronym
SALT
Website
SALT
Investigators
  • Prof. Nancy Pedersen
    Karolinska Institutet
  • Patrik Magnusson
    Karolinska Institutet
Contacts
  • Ulrika Zagai
    Karolinska Institutet

General Design

Study design
Cohort
Start Year
1998
End Year
2010
Recruitment Target
  • Families
Number of Participants
44,919
Number of Participants with Biological Samples
18,061
Supplementary Information
Magnusson PK, Almqvist C, Rahman I, et al. The Swedish Twin Registry: Establishment of a Biobank and Other Recent Developments. Twin Res Hum Genet 2012; 16: 317-29. Pubmed ID 23137839.

Access

Availability of data and biosamples

Possible Access to Data
Possible Access to Biosamples
Other
The SALT study as well as SALTY and Twin-Gene projects are part of the Swedish Twin Registry (STR). More information on studies within the registry and the data collected could be found at : https://ki.se/en/research/swedish-twin-registry-for-researchers.

Marker Paper

Lichtenstein P, Sullivan PF, Cnattingius S, et al. The Swedish Twin Registry in the third millennium: an update. Twin Res Hum Genet 2006; 9: 875-82.

PUBMED 17254424

Supplementary Information

The Swedish Twin Registry (STR) includes more than 190,000 twins - in principle all twins born in Sweden since 1886. The STR is made of three cohorts, each of which differs in method of ascertainment and extent of data collected: old cohort (born between 1886-1925), middle cohort (born between 1926-1958), and young cohort (born between 1959-1990). Same-sex twins from the old cohort were sent questionnaires in 1961, 1963, 1967, and 1970, and those from the middle cohort were sent a questionnaire in 1973.

SALT is a sub-study of the STR and it is a complete screening of all twins from this registry, regardless of gender composition or vital status of the pair and stems from the old and middle cohorts. In addition to the SALT interview, there was the TwinGene (2004-2008), SALTY (2009-2010) which included questionnaires and biosamples, and HARMONY (1998-2003) which included cognitive functioning screenings for those 65 and above, which have been conducted.

Timeline

Population

SALT population

Selection Criteria

Minimum age
40
Twins
Countries
  • Sweden

Sources of Recruitment

Specific Population
  • Other specific population : Swedish Twin Registry

Sample Size

Number of Participants
44,919
Number of Participants with Biological Samples
18,061
Supplementary Information

HARMONY: 14 164

TwinGene: 12 614 participants

SALTY: 11 372 participants

Data Collection Events

# Name Description Start End
0 SALT - CATI interview 1998 2002
1 SALT - HARMONY 1998 2003
2 SALT - TwinGene 2004 2008
3 SALT - SALTY 2009 2010

Individual Studies Included

Acronym Name Study design Participants Countries

Harmonization Projects Included

Acronym Name

Networks

Acronym Name Studies

Datasets

Name Type Data Collection Events Variables
Last Update: 2020-04-20 16:23