Seroprevalence of SARS-CoV-2 among African Canadians: Clinical and Epidemiological Correlates
The objectives of this study are:
* To determine the seroprevalence of COVID-19 infection among a population of African Canadians compared with seroprevalence rates in other populations in Canada.
* To determine the extent to which serological evidence of infection is associated with the presence of neutralizing antibodies.
* To examine the relationship between serological evidence of infection and medical comorbidities as well as socio-demographic variables.
* To determine the sustainability of seropositivity and neutralizing antibodies over a period of 24 months after the baseline determination of infection by serology.
Overview
- Acronym
- seroMARK
- Website
- seroMARK
- Investigators
-
- Contacts
-
General Design
- Study design
- Cross-sectional
- Start - End Year
- 2020 -
- General Information on Follow Up (profile, frequency)
-
After baseline, participants who had a negative result for antibodies will have a chance for a re-test at 4-6 months following baseline visit. Participants who had a positive test for antibodies, will be followed-up at 6, 12, 18, and 24 months.
- Recruitment Target
-
- Individuals
- Number of Participants
- 3,000
- Number of Participants with Biological Samples
- 3,000
- Supplementary information about number of participants
-
The study includes 2000 adults and children from African Canadian communities within Ontario along with 1000 non-African Canadians. Only 300 individuals less than 19 years old will be included.
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Timeline
Populations
seroMARK - African Canadians
The population is composed of 2 years old and older African Canadians residing in Ontario and COVID-19 symptom-free at the time of enrollment.
Selection Criteria
- Minimum age
-
2
- Countries
-
- Canada
- Canadian Provinces
-
- Ontario
- Ethnic Origin
-
- African Canadian
- Health Status
-
- Participants who are COVID-19 symptom-free at the time of enrollment are included.
Participants who present symptomatic respiratory tract infection or other symptoms consistent with COVID-19 are excluded.
- Participants who are COVID-19 symptom-free at the time of enrollment are included.
- Supplementary Information about selection criteria
-
300 participants are less than 19 years old.
Sources of Recruitment
- General Population
-
- Volunteer enrolment
- Specific Population
-
- Clinic patients
- Other specific population : African Canadians
- Supplementary Information
-
The majority of subjects are enrolled from the community. Some individuals are enrolled through hospitals. The 4 main models of enrollment based on the venues where subjects are enrolled are: * Model 1: hospitals * Model 2: community centre/church hall * Model 3: community health clinic * model 4: remote In model 1 (hospitals), the patient’s primary care team introduces the study. If the participant is interested in participating or obtaining more information, the research team would become engaged. Model 2 and Model 3 provide community venues where the study team enrolls participants and performs the study visit(s).
Sample Size
- Number of Participants
- 2,000
- Number of Participants with Biological Samples
- 2,000
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | seroMARK - African Canadians - Baseline |
|
|
2020 (December) | 2021 (March) |
| 1 | seroMARK - African Canadians - 4-6 month follow-up |
|
|
2021 (April) | 2021 (September) |
| 2 | seroMARK - African Canadians - 6 month follow-up |
|
|
2021 (June) | 2021 (September) |
| 3 | seroMARK - African Canadians - 12 month follow-up |
|
|
2021 (December) | 2022 (March) |
| 4 | seroMARK - African Canadians - 18 month follow-up |
|
|
2022 (June) | 2022 (September) |
| 5 | seroMARK - African Canadians - 24 month follow-up |
|
|
2022 (December) | 2023 (March) |
seroMARK - Non-African Canadians
The population is composed of 2 years and older non-African Canadians residing in Ontario who are COVID-19 symptom-free at the time of enrollment.
Selection Criteria
- Minimum age
-
2
- Countries
-
- Canada
- Canadian Provinces
-
- Ontario
- Health Status
-
- Participants who are COVID-19 symptom-free at the time of enrollment are included.
Participants who present symptomatic respiratory tract infection or other symptoms consistent with COVID-19 are excluded.
- Participants who are COVID-19 symptom-free at the time of enrollment are included.
- Supplementary Information about selection criteria
-
300 participants are less than 19 years of age.
Sources of Recruitment
- General Population
-
- Selected sample
- Supplementary Information
-
The majority of subjects are enrolled from the community. Some individuals are enrolled through hospitals. In this regard, 4 main models of enrollment based on the venues where subjects are enrolled are; * Model 1: hospitals * Model 2: community centre/church hall * Model 3: community health clinic * Model 4: remote. In model 1 (hospitals), the patient’s primary care team introduces the study. If the participant is interested in participating or obtaining more information, the research team would become engaged. Model 2 and Model 3 provide community venues where the study team enrolls participants and performs the study visit(s).
Sample Size
- Number of Participants
- 1,000
- Number of Participants with Biological Samples
- 1,000
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | seroMARK - Non-African Canadians - Baseline |
|
|
2020 (December) | 2021 (March) |
| 1 | seroMARK - Non-African Canadians - 4-6 month follow-up |
|
|
2021 (April) | 2021 (September) |
| 2 | seroMARK - Non-African Canadians - 6 month follow-up |
|
|
2021 (June) | 2021 (September) |
| 3 | seroMARK - Non-African Canadians - 12 month follow-up |
|
|
2021 (December) | 2022 (March) |
| 4 | seroMARK - Non-African Canadians - 18 month follow-up |
|
|
2022 (June) | 2022 (September) |
| 5 | seroMARK - Non-African Canadians - 24 month follow-up |
|
|
2022 (December) | 2023 (March) |
Participating Studies
| Acronym | Name | Study design | Countries |
|---|
Harmonization Initiatives Included
| Acronym | Name |
|---|
Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2024-04-01T14:12:40.589