Swiss Inflammatory Bowel Disease Cohort Study
The general aim of this study is to provide the Swiss and international scientific, public health and medical community with a disease-oriented prospective cohort of inflammatory bowel disease (IBD) patients.
The objectives are to:
* Provide up-to-date epidemiological data and investigate good or poor prognostic factors;
* Document medical care and health resource consumption to assess appropriateness of care and costs;
* Study psychosocial aspects linked to the disease, and the role of cytokines in the pro-inflammatory response to stress;
* Improve information and communication about the disease;
* Study microbiome composition, and how it is affected by risk and genetic factors
Overview
- Acronym
- SIBDCS
- Website
- SIBDCS
- Investigators
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- Contacts
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General Design
- Study design
- Cohort
- Start - End Year
- 2006 -
- General Information on Follow Up (profile, frequency)
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After baseline, participants are followed-up on a yearly basis as the cohort is still open.
- Recruitment Target
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- Individuals
- Number of Participants
- 4,300
- Number of Participants with Biological Samples
- 2,700
- Supplementary information about number of participants
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Baseline: 4387 participants
Follow-up 2007: 885 participants
Follow-up 2008: 1465 participants
Follow-up 2009: 1820 participants
Follow-up 2010: 2134 participants
Follow-up 2011: 2400 participants
Follow-up 2012: 2769 participants
Follow-up 2013: 2973 participants
Follow-up 2014: 3207 participants
Follow-up 2015: 3467 participants
Follow-up 2016: 3577 participants
Follow-up 2017: 2370 participants
Follow-up 2018: 2400 participants
Follow-up 2019: 3037 participants
Follow-up 2020: 2050 participants
Follow-up 2021: 3000 participants - Supplementary Information
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The SIBDCS is a longitudinal clinical cohort with an open design.
Access
Availability of data and biosamples
| Possible Access to Data | |
| Possible Access to Biosamples | |
| Other |
|
Information will be provided on the website (currently being updated).
Marker Papers
Pittet V, Juillerat P, Mottet C et al. Cohort profile: the Swiss Inflammatory Bowel Disease Cohort Study (SIBDCS). International Journal of Epidemiology. 2009;38(4):922-31
PUBMED 18782896Pittet V, Michetti P, Mueller C et al. Cohort Profile Update: The Swiss Inflammatory Bowel Disease Cohort Study (SIBDCS). International Journal of Epidemiology. 2019;48(2):385-386
PUBMED 30689927Timeline
Population
SIBDCS population
The population is composed of patients of all ages affected with inflammatory bowel diseases: Crohn disease, ulcerative colitis or indeterminate colitis, and who have a permanent residence status in Switzerland or have contracted Swiss health insurance and is treated on a regular basis for these diseases in Switzerland.
Selection Criteria
- Countries
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- Switzerland
- Health Status
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- Diagnosed with Crohn disease, ulcerative colitis or indeterminate colitis at least 2 months prior to inclusion or have had at least one recurrence of the symptoms.
- Other Criteria
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Participants are included if they have a permanent residence status in Switzerland or have contracted Swiss health insurance and is treated on a regular basis in Switzerland.
Participants are excluded if they have other form of colitis such as infectious colitis (positive culture or parasite search), ischemic colitis, radiation colitis, microscopic colitis, urogenital ulcer (Behçet's disease), eosinophilic enteritis (oeso-gastro or enteritis).
Sources of Recruitment
- Specific Population
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- Clinic patients
- Supplementary Information
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Recruitment first began in the six major inflammatory bowel disease centres of the university-based tertiary hospitals. Recruitment is fostered by providing information about the study and contacting gastroenterologists by mail or through informational meetings, either in regional or canton hospitals or in private practices. Recruitment of inflammatory bowel disease patients is carried out by their gastroenterologist, either during a routine visit or by mail invitation and is opened to any gastroenterologist practicing in Switzerland. A further channel of information about the study exists through patient organizations, so that patients can be recruited independently, for example those who have been in remission for a long time and who do not currently require any medical attention.
Sample Size
- Number of Participants
- 4,300
- Number of Participants with Biological Samples
- 2,700
Data Collection Events
| # | Name | Data sources | Data sources - Biosamples | Start | End |
|---|---|---|---|---|---|
| 0 | SIBDCS - Baseline |
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2006 | Ongoing |
| 1 | SIBDCS - Follow-up 2007 |
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|
2007 | Ongoing |
| 2 | SIBDCS - Follow-up 2008 |
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|
2008 | Ongoing |
| 3 | SIBDCS - Follow-up 2009 |
|
|
2009 | Ongoing |
| 4 | SIBDCS - Follow-up 2010 |
|
|
2010 | Ongoing |
| 5 | SIBDCS - Follow-up 2011 |
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2011 | Ongoing |
| 6 | SIBDCS - Follow-up 2012 |
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2012 | Ongoing |
| 7 | SIBDCS - Follow-up 2013 |
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2013 | Ongoing |
| 8 | SIBDCS - Follow-up 2014 |
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2014 | Ongoing |
| 9 | SIBDCS - Follow-up 2015 |
|
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2015 | Ongoing |
| 10 | SIBDCS - Follow-up 2016 |
|
|
2016 | Ongoing |
| 11 | SIBDCS - Follow-up 2017 |
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2017 | Ongoing |
| 12 | SIBDCS - Follow-up 2018 |
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2018 | Ongoing |
| 13 | SIBDCS - Follow-up 2019 |
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2019 | Ongoing |
| 14 | SIBDCS - Follow-up 2020 |
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2020 | Ongoing |
| 15 | SIBDCS - Follow-up 2021 |
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2021 | Ongoing |
Participating Studies
| Acronym | Name | Study design | Countries |
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Harmonization Initiatives Included
| Acronym | Name |
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Datasets
| Name | Data Collection Events | Variables |
|---|
Areas of Information Collected
- Socio-demographic and economic characteristics
- Death
- Lifestyle and behaviours
- Physical measures and assessments
- Birth, pregnancy and reproductive health history
- Laboratory measures
- Perception of health, quality of life, development and functional limitations
- Cognition, personality and psychological measures and assessments
- Diseases
- Life events, life plans, beliefs and values
- Symptoms and signs
- Preschool, school and work life
- Medication and supplements
- Social environment and relationships
- Non-pharmacological interventions
- Physical environment
- Health and community care services utilization
- Administrative information
Variables Content Summary
Areas of Information Collected
No Areas of Information Collected
No Scales Collected
Areas of Information Collected per per Population and Data Collection Event
No Areas of Information Collected
No Scales Collected
Networks
| Acronym | Name | Harmonization Initiatives | Individual Studies |
|---|
Last Update: 2024-04-15T15:55:53.087